The Natural History of Primary Inner Ear Schwannomas: Outcomes of Long-Term Follow-Up.
Journal
Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology
ISSN: 1537-4505
Titre abrégé: Otol Neurotol
Pays: United States
ID NLM: 100961504
Informations de publication
Date de publication:
01 12 2022
01 12 2022
Historique:
pubmed:
23
9
2022
medline:
15
11
2022
entrez:
22
9
2022
Statut:
ppublish
Résumé
To describe the natural history of primary inner ear schwannomas over a long follow-up period. Retrospective case series. Tertiary referral center. Patients with primary inner ear schwannomas with serial audiometric and radiologic follow-up. Patterns of hearing loss, rate of hearing decline, presence of vestibular symptoms, and rate of tumor growth. A total of 12 patients with 13 tumors were identified. The mean duration of follow-up was 7 years. Forty-six percent of tumors were intracochlear, 15% were intravestibular, 23% were transmodiolar, and 15% were intravestibular-cochlear. Hearing loss was the most common presenting symptom, occurring in all patients. Among patients with serviceable hearing (American Academy of Otolaryngology-Head and Neck Surgery Class A or B) at the time of presentation, the average time to decline to a nonserviceable hearing level was 57.3 months (range, 21-117 mo). Hearing loss was sudden in 31% of patients, progressive in 61% and fluctuating in 8%. No patients had intractable vertigo; however, two required vestibular physiotherapy. On initial magnetic resonance imaging, the mean largest tumor dimension was 3.1 mm (standard deviation, 1.2 mm), and the mean largest dimension on most recent magnetic resonance imaging was 4.4 mm (standard deviation, 1.1 mm). Two tumors exhibited no growth over a follow-up of 11.3 and 2.8 years, respectively. Overall, the mean growth was 0.25 mm per year followed. Two patients underwent cochlear implantation with simultaneous tumor resection and had favorable outcomes. Long-term follow-up suggests a conservative approach, with possible hearing rehabilitation at the time of deterioration, is a safe management strategy for primary inner ear schwannomas.
Identifiants
pubmed: 36136609
doi: 10.1097/MAO.0000000000003698
pii: 00129492-202212000-00041
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
e1168-e1173Informations de copyright
Copyright © 2022, Otology & Neurotology, Inc.
Déclaration de conflit d'intérêts
Sources of support and disclosure of funding : This study did not receive any funding from external sources. D.J. receives grant money from Advanced Bionics and is a consultant for Cochlear Corp. J.T.R. is on the advisory board for Cochlear Pty Limited. S.O.M. is an advisor for Advanced Bionics. There are no direct conflicts of interest related to the current study.
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