Changes in cardiopulmonary exercise capacity and limitations 3-12 months after COVID-19.


Journal

The European respiratory journal
ISSN: 1399-3003
Titre abrégé: Eur Respir J
Pays: England
ID NLM: 8803460

Informations de publication

Date de publication:
02 2023
Historique:
received: 08 04 2022
accepted: 27 08 2022
pubmed: 23 9 2022
medline: 7 2 2023
entrez: 22 9 2022
Statut: epublish

Résumé

To describe cardiopulmonary function during exercise 12 months after hospital discharge for coronavirus disease 2019 (COVID-19), assess the change from 3 to 12 months, and compare the results with matched controls without COVID-19. In this prospective, longitudinal, multicentre cohort study, hospitalised COVID-19 patients were examined using a cardiopulmonary exercise test (CPET) 3 and 12 months after discharge. At 3 months, 180 performed a successful CPET, and 177 did so at 12 months (mean age 59.3 years, 85 females). The COVID-19 patients were compared with controls without COVID-19 matched for age, sex, body mass index and comorbidity. Main outcome was peak oxygen uptake ( Exercise intolerance ( 1 year after hospital discharge for COVID-19, the majority (77%), had normal exercise capacity. Only every fourth had exercise intolerance and in these circulatory limiting factors were more common than ventilator factors. Deconditioning was common.

Identifiants

pubmed: 36137587
pii: 13993003.00745-2022
doi: 10.1183/13993003.00745-2022
pmc: PMC9515478
pii:
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Commentaires et corrections

Type : CommentIn

Informations de copyright

Copyright ©The authors 2023.

Déclaration de conflit d'intérêts

Conflict of interest: C.B. Ingul has received lecture fees from Bayer AS, unrelated to the current study. I. Skjørten has provided lectures for doctors’ education paid by Norwegian Directorate of Health and Norwegian Medical Association. G. Einvik has received research grants from AstraZeneca to perform the current study. A. Edvardsen has received payment or honoraria for lectures, presentations or educational events from GlaxoSmithKline and Chiesi. K. Stavem has received consulting fees from UCB Pharma and MSD, unrelated to the present study. All other authors have nothing to disclose.

Auteurs

Charlotte Björk Ingul (CB)

LHL Hospital Gardermoen, Jessheim, Norway.
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Faculty of Nursing and Health Sciences, Nord University, Bodø, Norway.

Anne Edvardsen (A)

LHL Hospital Gardermoen, Jessheim, Norway.
Pulmonary Department, Akershus University Hospital, Lørenskog, Norway.

Turid Follestad (T)

Department of Clinical and Molecular Medicine, Norwegian University of Science and Technology, Trondheim, Norway.

Divna Trebinjac (D)

LHL Hospital Gardermoen, Jessheim, Norway.

Odd Andre Wathne Ankerstjerne (OAW)

LHL Hospital Gardermoen, Jessheim, Norway.

Eivind Brønstad (E)

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Thoracic Department, St Olavs Hospital, Trondheim, Norway.

Øystein Rasch-Halvorsen (Ø)

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Thoracic Department, St Olavs Hospital, Trondheim, Norway.

Bernt Aarli (B)

Department of Clinical Science, University of Bergen, Bergen, Norway.
Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.

Håvard Dalen (H)

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.
Clinic of Cardiology, St Olavs University Hospital, Trondheim, Norway.
Department of Medicine, Levanger Hospital, Nord-Trøndelag Hospital Trust, Levanger, Norway.

Bjarne Martens Nes (BM)

Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, Trondheim, Norway.

Tøri Vigeland Lerum (TV)

Department of Pulmonary Medicine, Oslo University Hospital Ullevål, Oslo, Norway.
Institute for Clinical Medicine, University of Oslo, Oslo, Norway.

Gunnar Einvik (G)

Pulmonary Department, Akershus University Hospital, Lørenskog, Norway.
Institute for Clinical Medicine, University of Oslo, Oslo, Norway.

Knut Stavem (K)

Pulmonary Department, Akershus University Hospital, Lørenskog, Norway.
Institute for Clinical Medicine, University of Oslo, Oslo, Norway.
Health Services Research Unit, Akershus University Hospital, Lørenskog, Norway.

Ingunn Skjørten (I)

LHL Hospital Gardermoen, Jessheim, Norway.
Department of Pulmonary Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway.

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