Utility of the deep learning technique for the diagnosis of orbital invasion on CT in patients with a nasal or sinonasal tumor.

Deep learning Head and neck Nasal or sinonasal tumor Orbital invasion Periorbita Transfer learning

Journal

Cancer imaging : the official publication of the International Cancer Imaging Society
ISSN: 1470-7330
Titre abrégé: Cancer Imaging
Pays: England
ID NLM: 101172931

Informations de publication

Date de publication:
22 Sep 2022
Historique:
received: 20 04 2022
accepted: 14 09 2022
entrez: 22 9 2022
pubmed: 23 9 2022
medline: 28 9 2022
Statut: epublish

Résumé

In nasal or sinonasal tumors, orbital invasion beyond periorbita by the tumor is one of the important criteria in the selection of the surgical procedure. We investigated the usefulness of the convolutional neural network (CNN)-based deep learning technique for the diagnosis of orbital invasion, using computed tomography (CT) images. A total of 168 lesions with malignant nasal or sinonasal tumors were divided into a training dataset (n = 119) and a test dataset (n = 49). The final diagnosis (invasion-positive or -negative) was determined by experienced radiologists who carefully reviewed all of the CT images. In a CNN-based deep learning analysis, a slice of the square target region that included the orbital bone wall was extracted and fed into a deep-learning training session to create a diagnostic model using transfer learning with the Visual Geometry Group 16 (VGG16) model. The test dataset was subsequently tested in CNN-based diagnostic models and by two other radiologists who were not specialized in head and neck radiology. At approx. 2 months after the first reading session, two radiologists again reviewed all of the images in the test dataset, referring to the diagnoses provided by the trained CNN-based diagnostic model. The diagnostic accuracy was 0.92 by the CNN-based diagnostic models, whereas the diagnostic accuracies by the two radiologists at the first reading session were 0.49 and 0.45, respectively. In the second reading session by two radiologists (diagnosing with the assistance by the CNN-based diagnostic model), marked elevations of the diagnostic accuracy were observed (0.94 and 1.00, respectively). The CNN-based deep learning technique can be a useful support tool in assessing the presence of orbital invasion on CT images, especially for non-specialized radiologists.

Sections du résumé

BACKGROUND BACKGROUND
In nasal or sinonasal tumors, orbital invasion beyond periorbita by the tumor is one of the important criteria in the selection of the surgical procedure. We investigated the usefulness of the convolutional neural network (CNN)-based deep learning technique for the diagnosis of orbital invasion, using computed tomography (CT) images.
METHODS METHODS
A total of 168 lesions with malignant nasal or sinonasal tumors were divided into a training dataset (n = 119) and a test dataset (n = 49). The final diagnosis (invasion-positive or -negative) was determined by experienced radiologists who carefully reviewed all of the CT images. In a CNN-based deep learning analysis, a slice of the square target region that included the orbital bone wall was extracted and fed into a deep-learning training session to create a diagnostic model using transfer learning with the Visual Geometry Group 16 (VGG16) model. The test dataset was subsequently tested in CNN-based diagnostic models and by two other radiologists who were not specialized in head and neck radiology. At approx. 2 months after the first reading session, two radiologists again reviewed all of the images in the test dataset, referring to the diagnoses provided by the trained CNN-based diagnostic model.
RESULTS RESULTS
The diagnostic accuracy was 0.92 by the CNN-based diagnostic models, whereas the diagnostic accuracies by the two radiologists at the first reading session were 0.49 and 0.45, respectively. In the second reading session by two radiologists (diagnosing with the assistance by the CNN-based diagnostic model), marked elevations of the diagnostic accuracy were observed (0.94 and 1.00, respectively).
CONCLUSION CONCLUSIONS
The CNN-based deep learning technique can be a useful support tool in assessing the presence of orbital invasion on CT images, especially for non-specialized radiologists.

Identifiants

pubmed: 36138422
doi: 10.1186/s40644-022-00492-0
pii: 10.1186/s40644-022-00492-0
pmc: PMC9502604
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

52

Informations de copyright

© 2022. The Author(s).

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Auteurs

Junichi Nakagawa (J)

Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan.

Noriyuki Fujima (N)

Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan. fujima@med.hokudai.ac.jp.

Kenji Hirata (K)

Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Department of Nuclear Medicine, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan.
Clinical AI Human Resources Development Program, Faculty of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.

Minghui Tang (M)

Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Clinical AI Human Resources Development Program, Faculty of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.

Satonori Tsuneta (S)

Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan.

Jun Suzuki (J)

Department of Radiology, Teine Keijinkai Hospital, 1-40, Maeda 1-12, Teine-ku, Sapporo, Hokkaido, 006-8555, Japan.

Taisuke Harada (T)

Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan.

Yohei Ikebe (Y)

Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan.
Center for Cause of Death investigation, Faculty of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.

Akihiro Homma (A)

Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N15 W7, Kita ku, Sapporo, 060-8638, Japan.

Satoshi Kano (S)

Department of Otolaryngology-Head and Neck Surgery, Faculty of Medicine and Graduate School of Medicine, Hokkaido University, N15 W7, Kita ku, Sapporo, 060-8638, Japan.

Kazuyuki Minowa (K)

Faculty of Dental Medicine, Department of Radiology, Hokkaido University, N13 W7, Kita-ku, Sapporo, Hokkaido, 060-8586, Japan.

Kohsuke Kudo (K)

Department of Diagnostic Imaging, Graduate School of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Department of Diagnostic and Interventional Radiology, Hokkaido University Hospital, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8648, Japan.
Clinical AI Human Resources Development Program, Faculty of Medicine, Hokkaido University, N15 W7, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.
Global Center for Biomedical Science and Engineering, Faculty of Medicine, Hokkaido University, N14 W5, Kita-Ku, Sapporo, Hokkaido, 060-8638, Japan.

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