Inhibition of KRAS, MEK and PI3K Demonstrate Synergistic Anti-Tumor Effects in Pancreatic Ductal Adenocarcinoma Cell Lines.

KRAS gene expression kinase inhibitors pancreatic ductal adenocarcinoma

Journal

Cancers
ISSN: 2072-6694
Titre abrégé: Cancers (Basel)
Pays: Switzerland
ID NLM: 101526829

Informations de publication

Date de publication:
14 09 2022
Historique:
received: 26 08 2022
revised: 12 09 2022
accepted: 12 09 2022
entrez: 23 9 2022
pubmed: 24 9 2022
medline: 24 9 2022
Statut: epublish

Résumé

Kirsten rat sarcoma virus (

Identifiants

pubmed: 36139627
pii: cancers14184467
doi: 10.3390/cancers14184467
pmc: PMC9497071
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : European Community
ID : TBI-V-1-241-VBW-084

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Auteurs

Yixuan Ma (Y)

Department of Medicine Clinic III, Hematology, Oncology and Palliative Medicine, Rostock University Medical Center, 18057 Rostock, Germany.

Benjamin Schulz (B)

Institute for Experimental Surgery, Rostock University Medical Center, 18057 Rostock, Germany.

Nares Trakooljul (N)

Institute of Genome Biology, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.

Moosheer Al Ammar (M)

Department of Medicine Clinic III, Hematology, Oncology and Palliative Medicine, Rostock University Medical Center, 18057 Rostock, Germany.

Anett Sekora (A)

Department of Medicine Clinic III, Hematology, Oncology and Palliative Medicine, Rostock University Medical Center, 18057 Rostock, Germany.

Sina Sender (S)

Department of Medicine Clinic III, Hematology, Oncology and Palliative Medicine, Rostock University Medical Center, 18057 Rostock, Germany.

Frieder Hadlich (F)

Institute of Genome Biology, Research Institute for Farm Animal Biology (FBN), 18196 Dummerstorf, Germany.

Dietmar Zechner (D)

Institute for Experimental Surgery, Rostock University Medical Center, 18057 Rostock, Germany.

Frank Ulrich Weiss (FU)

Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.

Markus M Lerch (MM)

Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany.
Ludwig Maximilian University Hospital, Ludwig Maximilian University of Munich, 81377 Munich, Germany.

Robert Jaster (R)

Department of Medicine II, Division of Gastroenterology, Rostock University Medical Center, 18057 Rostock, Germany.

Christian Junghanss (C)

Department of Medicine Clinic III, Hematology, Oncology and Palliative Medicine, Rostock University Medical Center, 18057 Rostock, Germany.

Hugo Murua Escobar (H)

Department of Medicine Clinic III, Hematology, Oncology and Palliative Medicine, Rostock University Medical Center, 18057 Rostock, Germany.

Classifications MeSH