NADPH Oxidases in Aortic Aneurysms.
NADPH oxidases/NOX
aortic aneurysm
reactive oxygen species
Journal
Antioxidants (Basel, Switzerland)
ISSN: 2076-3921
Titre abrégé: Antioxidants (Basel)
Pays: Switzerland
ID NLM: 101668981
Informations de publication
Date de publication:
16 Sep 2022
16 Sep 2022
Historique:
received:
10
08
2022
revised:
08
09
2022
accepted:
12
09
2022
entrez:
23
9
2022
pubmed:
24
9
2022
medline:
24
9
2022
Statut:
epublish
Résumé
Abdominal aortic aneurysms (AAAs) are a progressive dilation of the infrarenal aorta and are characterized by inflammatory cell infiltration, smooth muscle cell migration and proliferation, and degradation of the extracellular matrix. Oxidative stress and the production of reactive oxygen species (ROS) have been shown to play roles in inflammatory cell infiltration, and smooth muscle cell migration and apoptosis in AAAs. In this review, we discuss the principles of nicotinamide adenine dinucleotide phosphate oxidase (NADPH oxidase/NOX) signaling and activation. We also discuss the effects of some of the major mediators of NOX signaling in AAAs. Separately, we also discuss the influence of genetic or pharmacologic inhibitors of NADPH oxidases on experimental pre-clinical AAAs. Experimental evidence suggests that NADPH oxidases may be a promising future therapeutic target for developing pharmacologic treatment strategies for halting AAA progression or rupture prevention in the management of clinical AAAs.
Identifiants
pubmed: 36139902
pii: antiox11091830
doi: 10.3390/antiox11091830
pmc: PMC9495752
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Subventions
Organisme : American Heart Association
ID : 14SDG18730000
Références
Eur J Vasc Endovasc Surg. 2014 Sep;48(3):276-83
pubmed: 24913683
Lancet. 2002 Nov 16;360(9345):1531-9
pubmed: 12443589
Br J Surg. 1995 Aug;82(8):1066-70
pubmed: 7648155
Front Surg. 2016 Jan 25;3:1
pubmed: 26835458
JAMA. 2020 May 26;323(20):2029-2038
pubmed: 32453369
J Biochem. 2000 Nov;128(5):777-83
pubmed: 11056390
Circ Res. 2010 Apr 16;106(7):1253-64
pubmed: 20185797
Circulation. 2002 Mar 26;105(12):1429-35
pubmed: 11914250
Free Radic Biol Med. 2007 Feb 15;42(4):446-59
pubmed: 17275676
Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H24-32
pubmed: 19837950
Free Radic Biol Med. 2020 Feb 20;148:60-69
pubmed: 31883469
Mol Endocrinol. 2007 Jul;21(7):1593-602
pubmed: 17440044
BMC Genomics. 2009 Jul 06;10:298
pubmed: 19580648
Curr Drug Targets. 2018;19(11):1256-1264
pubmed: 28925872
Planta Med. 2013 Mar;79(3-4):244-52
pubmed: 23345167
Am J Physiol. 1996 Oct;271(4 Pt 2):H1626-34
pubmed: 8897960
Pharmacol Ther. 2008 Dec;120(3):254-91
pubmed: 18804121
Genes Dev. 2004 Mar 1;18(5):486-91
pubmed: 15014044
Int J Cardiol. 2013 Oct 3;168(3):2389-96
pubmed: 23506637
Antioxid Redox Signal. 2015 Aug 10;23(5):460-89
pubmed: 24635113
Ann N Y Acad Sci. 2006 Nov;1085:306-10
pubmed: 17182947
J Biol Chem. 2011 Apr 15;286(15):13304-13
pubmed: 21343298
Arterioscler Thromb Vasc Biol. 2011 Dec;31(12):3011-9
pubmed: 21940941
Atherosclerosis. 2009 Jan;202(1):128-34
pubmed: 18502427
Atherosclerosis. 2011 Aug;217(2):350-7
pubmed: 21530968
Biomed Res Int. 2020 Aug 22;2020:9485398
pubmed: 32908926
Annu Rev Med. 2017 Jan 14;68:51-67
pubmed: 28099082
Am Heart J. 2009 Feb;157(2):319-26
pubmed: 19185640
Br J Surg. 2020 Oct;107(11):1459-1467
pubmed: 32391589
Cell Res. 2011 Jan;21(1):103-15
pubmed: 21187859
Cardiovasc Res. 2005 Feb 1;65(2):495-504
pubmed: 15639489
Antioxid Redox Signal. 2006 May-Jun;8(5-6):691-728
pubmed: 16771662
Bioorg Med Chem. 2011 Dec 1;19(23):6989-99
pubmed: 22041175
Circulation. 2006 Mar 21;113(11):e463-654
pubmed: 16549646
Redox Biol. 2019 Sep;26:101273
pubmed: 31325723
Eur J Vasc Endovasc Surg. 2021 Jun;61(6):1030
pubmed: 33836975
Circulation. 2006 Dec 12;114(24):2611-8
pubmed: 17145990
Circ Res. 2013 Jul 19;113(3):327-40
pubmed: 23868829
Redox Biol. 2018 Jun;16:285-293
pubmed: 29571125
Am J Physiol Cell Physiol. 2002 Apr;282(4):C926-34
pubmed: 11880281
Sci Rep. 2016 Jul 01;6:28612
pubmed: 27363580
J Cardiol. 2012 May;59(3):299-306
pubmed: 22365948
Mol Cell Biol. 2004 Dec;24(24):10703-17
pubmed: 15572675
J Intern Med. 2020 Jul;288(1):23-37
pubmed: 32187752
Ann N Y Acad Sci. 1996 Nov 18;800:1-24
pubmed: 8958978
Circ Res. 2003 Jun 13;92(11):e80-6
pubmed: 12750313
Br J Surg. 2012 Dec;99(12):1649-56
pubmed: 23034729
Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2389-96
pubmed: 23950141
Circulation. 2002 Jan 22;105(3):293-6
pubmed: 11804982
Circulation. 2004 Jan 6;109(1):132-8
pubmed: 14662712
Circ Res. 2002 Jun 14;90(11):1205-13
pubmed: 12065324
Cardiovasc Res. 2013 Jan 1;97(1):106-14
pubmed: 23015640
Hypertension. 2012 Jan;59(1):158-66
pubmed: 22083158
Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2380-8
pubmed: 23950142
Circulation. 2015 Oct 27;132(17):1620-9
pubmed: 26338955
Physiol Rev. 2007 Jan;87(1):245-313
pubmed: 17237347
Eur J Vasc Endovasc Surg. 1999 Jun;17(6):472-5
pubmed: 10375481
J Vasc Surg. 2010 Sep;52(3):539-48
pubmed: 20630687
Oxid Med Cell Longev. 2019 Apr 18;2019:3264858
pubmed: 31178956
Br J Pharmacol. 2001 Oct;134(4):865-70
pubmed: 11606327
J Biol Chem. 2001 Oct 5;276(40):37594-601
pubmed: 11483596
Curr Drug Targets. 2012 Feb;13(2):199-206
pubmed: 22204319
Free Radic Biol Med. 2018 Apr;118:44-58
pubmed: 29471108
J Vasc Res. 2008;45(3):251-8
pubmed: 18182824
Hypertension. 2007 Jul;50(1):189-96
pubmed: 17502491
Circulation. 2006 Aug 1;114(5):404-413
pubmed: 16864727
Vascul Pharmacol. 2012 May-Jun;56(5-6):216-31
pubmed: 22405985
PLoS One. 2017 Aug 3;12(8):e0181500
pubmed: 28771483
Arterioscler Thromb Vasc Biol. 2007 Mar;27(3):461-9
pubmed: 17218601
Ann N Y Acad Sci. 2012 Apr;1254:164-174
pubmed: 22548582
J Biol Chem. 1999 Jul 9;274(28):19731-7
pubmed: 10391914
Circulation. 2005 Apr 5;111(13):1637-44
pubmed: 15795323
J Vasc Surg. 2018 Nov;68(5):1538-1550.e2
pubmed: 29242064
J Vasc Surg. 2005 Jan;41(1):108-14
pubmed: 15696052
J Vasc Surg. 1995 Jun;21(6):985-8
pubmed: 7776479
Circ Res. 2000 Jul 7;87(1):26-32
pubmed: 10884368
Am J Physiol Renal Physiol. 2015 Jun 1;308(11):F1276-87
pubmed: 25656366
Free Radic Biol Med. 2013 Aug;61:473-501
pubmed: 23583330
J Biol Chem. 2000 Jul 28;275(30):23227-33
pubmed: 10806195
Redox Biol. 2020 Jul;34:101512
pubmed: 32480354
J Biol Chem. 1999 Dec 24;274(52):37265-9
pubmed: 10601291
Circ Res. 2001 May 11;88(9):947-53
pubmed: 11349005
J Vasc Surg. 2003 Aug;38(2):360-7
pubmed: 12891121
Biochem Biophys Res Commun. 2005 Dec 9;338(1):677-86
pubmed: 16157295
Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):560-5
pubmed: 11950691
Proc Natl Acad Sci U S A. 1998 Jul 7;95(14):7993-8
pubmed: 9653128
Front Cardiovasc Med. 2022 Jun 30;9:904215
pubmed: 35845076
Neurol Res. 2012 May;34(4):338-45
pubmed: 22643077
J Biol Chem. 1995 Nov 3;270(44):26246-51
pubmed: 7592831
Diagnostics (Basel). 2022 Jan 13;12(1):
pubmed: 35054350
Sci Rep. 2022 Jul 7;12(1):11570
pubmed: 35798762
J Patient Rep Outcomes. 2018 Sep 04;2:37
pubmed: 30238082
Am Fam Physician. 2006 Apr 1;73(7):1198-204
pubmed: 16623206
PLoS One. 2018 Sep 28;13(9):e0204271
pubmed: 30265686
Arterioscler Thromb Vasc Biol. 2002 Dec 1;22(12):2037-43
pubmed: 12482831
Antioxid Redox Signal. 2015 Aug 10;23(5):358-74
pubmed: 26135714
Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):653-61
pubmed: 19910640
Prog Cardiovasc Dis. 2013 Jul-Aug;56(1):74-80
pubmed: 23993240
J Biol Chem. 2004 Apr 30;279(18):18583-91
pubmed: 14982937
FEBS Lett. 2005 Apr 25;579(11):2533-40
pubmed: 15848200
J Biol Chem. 2002 Mar 22;277(12):10121-8
pubmed: 11796733
Arterioscler Thromb Vasc Biol. 2007 Jan;27(1):42-8
pubmed: 17082491
Free Radic Biol Med. 2010 Dec 15;49(12):2040-8
pubmed: 21146788
J Am Coll Cardiol. 2010 Mar 2;55(9):841-57
pubmed: 20185035
Antioxid Redox Signal. 2011 Aug 1;15(3):607-19
pubmed: 21391892
Molecules. 2018 Mar 14;23(3):
pubmed: 29538284
Redox Biol. 2019 Apr;22:101143
pubmed: 30897521
J Thorac Cardiovasc Surg. 2003 Aug;126(2):344-57; discission 357
pubmed: 12928630
Cardiovasc Res. 2003 Oct 1;59(4):988-96
pubmed: 14553839
Arterioscler Thromb Vasc Biol. 2016 May;36(5):908-18
pubmed: 26988591
Redox Biol. 2017 Apr;11:118-125
pubmed: 27912196
Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L913-L923
pubmed: 27612966
Biol Pharm Bull. 2019 Sep 1;42(9):1464-1470
pubmed: 31270287
J Enzyme Inhib Med Chem. 2013 Feb;28(1):95-104
pubmed: 22136506
Am J Physiol Cell Physiol. 2005 Apr;288(4):C899-905
pubmed: 15590897
J Vasc Surg. 2005 Mar;41(3):479-89
pubmed: 15838484
Int J Vasc Med. 2013;2013:267215
pubmed: 23401778
N Engl J Med. 2014 Nov 27;371(22):2101-8
pubmed: 25427112
Free Radic Biol Med. 2008 Aug 1;45(3):329-35
pubmed: 18466778
Biochem J. 2005 Aug 15;390(Pt 1):199-206
pubmed: 15819614
Nat Rev Immunol. 2004 Mar;4(3):181-9
pubmed: 15039755
Br J Surg. 2002 Mar;89(3):283-5
pubmed: 11872050
J Cardiovasc Med (Hagerstown). 2009 Apr;10(4):354-62
pubmed: 19430350
Ann Vasc Surg. 2017 May;41:265-270
pubmed: 27908811
Science. 2006 Apr 7;312(5770):117-21
pubmed: 16601194
J Mol Cell Cardiol. 2009 Dec;47(6):752-60
pubmed: 19660467
J Biol Chem. 1998 Apr 17;273(16):9539-43
pubmed: 9545283
ACS Chem Biol. 2010 Oct 15;5(10):981-93
pubmed: 20715845
Arch Intern Med. 2000 May 22;160(10):1425-30
pubmed: 10826454
Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10650-4
pubmed: 7938008
Arch Intern Med. 2000 Apr 24;160(8):1117-21
pubmed: 10789604
Ann Neurol. 2008 Dec;64(6):654-63
pubmed: 19107988
Arterioscler Thromb Vasc Biol. 2014 Nov;34(11):2413-20
pubmed: 25189573
Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4474-9
pubmed: 12672956
Cell Mol Life Sci. 2002 Sep;59(9):1428-59
pubmed: 12440767
Circulation. 2018 Feb 6;137(6):636-638
pubmed: 29431665
Redox Biol. 2019 Feb;21:101063
pubmed: 30576919
Redox Rep. 2012;17(4):139-44
pubmed: 22732574