Analysis of Risk Factors for Phonation Disorders after Thyroid Surgery.

complications risk factors thyroid surgery vocal cord paralysis

Journal

Biomedicines
ISSN: 2227-9059
Titre abrégé: Biomedicines
Pays: Switzerland
ID NLM: 101691304

Informations de publication

Date de publication:
14 Sep 2022
Historique:
received: 23 08 2022
revised: 04 09 2022
accepted: 07 09 2022
entrez: 23 9 2022
pubmed: 24 9 2022
medline: 24 9 2022
Statut: epublish

Résumé

Phonation disorders after thyroidectomy are among the most common complications and occur as a result of recurrent laryngeal nerve (RLN) injury. The multivariate analysis of risk factors for phonation disorders after thyroidectomy was assessed. A group of 830 patients with 1500 RLNs at risk of injury during thyroidectomy were analyzed retrospectively. The impact of the method of RLN identification, age, sex, BMI, kind of thyroid surgery, pathology, surgeon's experience and thyroid volume on vocal cord paralysis was analyzed. We found that the retrosternal goiter and the volume above 100 mL were the most important risk factors for both transient and permanent paralysis. Thyroid cancer had a statistically significant impact on the increase in permanent paralysis, while this indication had practically no impact on transient paralysis. Among patients over 65 years with obesity, the probability of transient complications approximately doubled, with no effect on the permanent paralysis. Men were approximately 1.7 times more likely to develop any type of phonation disorder. Secondary operations more than doubled the risk of transient and permanent vocal cord paralysis. Thyroidectomy with only visual RLN identification was associated with a risk of both transient and permanent vocal cord paralysis almost two times higher, compared to neuromonitoring.

Identifiants

pubmed: 36140379
pii: biomedicines10092280
doi: 10.3390/biomedicines10092280
pmc: PMC9496448
pii:
doi:

Types de publication

Journal Article

Langues

eng

Références

Mol Cell Endocrinol. 2010 Mar 25;316(2):165-71
pubmed: 19540303
Br J Surg. 2009 Mar;96(3):240-6
pubmed: 19177420
Medicine (Baltimore). 2020 Oct 30;99(44):e23003
pubmed: 33126382
Laryngoscope. 2019 Jan;129(1):275-283
pubmed: 30284255
Khirurgiia (Mosk). 2019;(4):5-14
pubmed: 31120441
Curr Opin Otolaryngol Head Neck Surg. 2016 Jun;24(3):197-202
pubmed: 27092906
Cochrane Database Syst Rev. 2019 Jan 19;1:CD012483
pubmed: 30659577
World J Surg. 2017 Oct;41(10):2521-2529
pubmed: 28466363
Chirurg. 1991 Mar;62(3):182-7; discussion 188
pubmed: 2036893
World J Surg. 2019 Sep;43(9):2228-2234
pubmed: 31065775
World J Surg. 2004 Mar;28(3):271-6
pubmed: 14961204
Langenbecks Arch Surg. 2008 Sep;393(5):667-73
pubmed: 18633639
Arch Surg. 2006 Jan;141(1):82-5
pubmed: 16415416
Medicine (Baltimore). 2017 Feb;96(5):e5752
pubmed: 28151852
BMC Surg. 2020 Nov 7;20(1):275
pubmed: 33160350
Surgery. 2006 Mar;139(3):357-62
pubmed: 16546500
Laryngoscope. 2013 Sep;123 Suppl 4:S1-14
pubmed: 23832799
Laryngoscope. 2011 Jan;121 Suppl 1:S1-16
pubmed: 21181860
Head Neck. 2017 Jul;39(7):1470-1478
pubmed: 28370683
Br J Cancer. 2006 Aug 7;95(3):366-70
pubmed: 16832414
Medicine (Baltimore). 2017 Apr;96(17):e6674
pubmed: 28445266
Ann Surg Oncol. 2011 Aug;18(8):2251-9
pubmed: 21336513
J Surg Res. 2020 Nov;255:42-49
pubmed: 32540579
Laryngoscope. 2002 Jan;112(1):124-33
pubmed: 11802050
Ann Surg. 2004 Jul;240(1):18-25
pubmed: 15213613
Surgery. 2014 Nov;156(5):1145-52
pubmed: 24878452
Otolaryngol Head Neck Surg. 2013 Jun;148(6 Suppl):S1-37
pubmed: 23733893
Surgery. 2017 Apr;161(4):1129-1138
pubmed: 27989608
J Visc Surg. 2014 Jun;151(3):183-9
pubmed: 24880605
Int J Clin Pract. 2009 Apr;63(4):624-9
pubmed: 19335706
Surgery. 2004 Dec;136(6):1310-22
pubmed: 15657592
World J Surg. 2000 Nov;24(11):1335-41
pubmed: 11038203
Langenbecks Arch Surg. 2018 Nov;403(7):811-823
pubmed: 30430230
Surgery. 2006 Dec;140(6):866-72; discussion 872-3
pubmed: 17188132
Curr Opin Otolaryngol Head Neck Surg. 2014 Dec;22(6):444-9
pubmed: 25254404

Auteurs

Mateusz Głód (M)

Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.

Dominik Marciniak (D)

Department of Dosage Form Technology, Wroclaw Medical University, Borowska Street 211 A, 50-556 Wroclaw, Poland.

Krzysztof Kaliszewski (K)

Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.

Krzysztof Sutkowski (K)

Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.

Jerzy Rudnicki (J)

Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.

Marek Bolanowski (M)

Department of Endocrinology, Diabetes and Isotope Therapy, Wroclaw Medical University, Pasteura Street 4, 50-367 Wroclaw, Poland.

Beata Wojtczak (B)

Department of General, Minimally Invasive and Endocrine Surgery, Wroclaw Medical University, Borowska Street 213, 50-556 Wroclaw, Poland.

Classifications MeSH