apoptosis
cell death
erythropoiesis
globin
hemoglobin
thalassemia
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
13 Sep 2022
13 Sep 2022
Historique:
received:
16
07
2022
revised:
30
08
2022
accepted:
06
09
2022
entrez:
23
9
2022
pubmed:
24
9
2022
medline:
24
9
2022
Statut:
epublish
Résumé
Defective hemoglobin production and ineffective erythropoiesis contribute to the pathophysiology of thalassemia syndromes. Previous studies in the field of erythropoiesis mainly focused on the severe forms of thalassemia, such as β-thalassemia major, while mechanisms underlying the pathogenesis of other thalassemia syndromes remain largely unexplored. The current study aimed to investigate the intrinsic pathophysiological properties of erythroid cells derived from the most common forms of thalassemia diseases, including α-thalassemia (hemoglobin H and hemoglobin H-Constant Spring diseases) and β-thalassemia (homozygous β
Identifiants
pubmed: 36143003
pii: jcm11185356
doi: 10.3390/jcm11185356
pmc: PMC9504363
pii:
doi:
Types de publication
Journal Article
Langues
eng
Références
Hematol Oncol Clin North Am. 2018 Apr;32(2):213-221
pubmed: 29458727
J Transl Med. 2011 Jun 25;9:96
pubmed: 21702968
Cell. 1995 Jan 27;80(2):285-91
pubmed: 7834748
Haematologica. 2020 Jun 05;105(9):2240-2249
pubmed: 33054049
Blood. 2000 Nov 15;96(10):3624-9
pubmed: 11071663
Haematologica. 2021 Jun 01;106(6):1519-1534
pubmed: 33832207
Exp Hematol. 2000 Dec;28(12):1343-53
pubmed: 11146156
Hematology Am Soc Hematol Educ Program. 2009;:26-34
pubmed: 20008179
Blood. 2008 Aug 1;112(3):875-85
pubmed: 18480424
PeerJ. 2018 Aug 31;6:e5527
pubmed: 30186694
Blood Cells Mol Dis. 2012 Feb 15;48(2):77-85
pubmed: 22154201
Ann Hematol. 2008 May;87(5):375-9
pubmed: 18026953
Hematol Oncol Clin North Am. 2016 Apr;30(2):359-71
pubmed: 27040959
Lancet. 2018 Jan 13;391(10116):155-167
pubmed: 28774421
Acta Haematol. 2011;126(4):224-30
pubmed: 21934298
Blood. 2000 Oct 1;96(7):2606-12
pubmed: 11001918
Biochem Biophys Res Commun. 2005 Jul 29;333(2):336-43
pubmed: 15922292
J Clin Med. 2022 Mar 22;11(7):
pubmed: 35407362
Nature. 2014 Oct 9;514(7521):242-6
pubmed: 25156257
N Engl J Med. 1999 Jul 8;341(2):99-109
pubmed: 10395635
Eur J Cell Biol. 2008 May;87(5):325-34
pubmed: 18375015
Cell Death Dis. 2020 Jan 6;11(1):8
pubmed: 31907357
Br J Haematol. 2016 Nov;175(3):539-542
pubmed: 26763683
Nature. 2007 Jan 4;445(7123):102-5
pubmed: 17167422
J Biol Chem. 1997 Sep 26;272(39):24101-4
pubmed: 9305851
Blood. 1997 Mar 1;89(5):1762-9
pubmed: 9057661
Southeast Asian J Trop Med Public Health. 2005 Sep;36(5):1298-303
pubmed: 16438161
Cold Spring Harb Perspect Med. 2012 Aug 01;2(8):
pubmed: 22908199
Acta Haematol. 2021;144(6):660-671
pubmed: 34535581
Blood. 1993 Jul 15;82(2):374-7
pubmed: 8329696
Br J Haematol. 2009 Sep;146(5):557-68
pubmed: 19594742