Enhanced Photodynamic Efficacy Using 1,8-Naphthalimides: Potential Application in Antibacterial Photodynamic Therapy.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
06 Sep 2022
Historique:
received: 08 07 2022
revised: 30 08 2022
accepted: 31 08 2022
entrez: 23 9 2022
pubmed: 24 9 2022
medline: 28 9 2022
Statut: epublish

Résumé

This study addresses the need for antibacterial medication that can overcome the current problems of antibiotics. It does so by suggesting two 1,8-naphthalimides (NI1 and NI2) containing a pyridinium nucleus become attached to the imide-nitrogen atom via a methylene spacer. Those fluorescent derivatives are covalently bonded to the surface of a chloroacetyl-chloride-modified cotton fabric. The iodometric method was used to study the generation of singlet oxygen (

Identifiants

pubmed: 36144479
pii: molecules27185743
doi: 10.3390/molecules27185743
pmc: PMC9504615
pii:
doi:

Substances chimiques

Anti-Bacterial Agents 0
Chlorides 0
Naphthalimides 0
Singlet Oxygen 17778-80-2
Nitrogen N762921K75

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Bulgarian Science Fund
ID : № КП-06-H49/2

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Auteurs

Desislava Staneva (D)

Department of Textile, Leader and Fuels, University of Chemical Technology and Metallurgy, 1756 Sofia, Bulgaria.

Awad I Said (AI)

Chemistry Department, Faculty of Science, Assiut University, Assiut 71516, Egypt.
Department of Chemistry and Biochemistry, Physiology and Pathophysiology, Faculty of Medicine, Sofia University "St. Kliment Ohridski", 1407 Sofia, Bulgaria.

Evgenia Vasileva-Tonkova (E)

The Stephan Angeloff Institute of Microbiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria.

Ivo Grabchev (I)

Department of Chemistry and Biochemistry, Physiology and Pathophysiology, Faculty of Medicine, Sofia University "St. Kliment Ohridski", 1407 Sofia, Bulgaria.

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Classifications MeSH