Mapping the Prevalence of COVID-19 Vaccine Acceptance at the Global and Regional Level: A Systematic Review and Meta-Analysis.

COVID-19 meta-analysis systematic review vaccination vaccine hesitancy

Journal

Vaccines
ISSN: 2076-393X
Titre abrégé: Vaccines (Basel)
Pays: Switzerland
ID NLM: 101629355

Informations de publication

Date de publication:
07 Sep 2022
Historique:
received: 04 08 2022
revised: 29 08 2022
accepted: 30 08 2022
entrez: 23 9 2022
pubmed: 24 9 2022
medline: 24 9 2022
Statut: epublish

Résumé

Despite the availability of effective and safe vaccines, the acceptance of COVID-19 vaccination is suboptimal. In this meta-analysis we quantified the prevalence estimates of COVID-19 vaccine acceptance with a specific focus on worldwide geographical differences. We searched PubMed, Scopus, Web of Science and PsycInfo up to April 2021 (PROSPERO ID: CRD42021235328). Generalized random-effects linear models with a logit link were used to calculate the pooled estimated rate of vaccine acceptance at both the global and regional level. A meta-regression analysis was performed to assess the association between COVID-19 vaccine acceptance and various characteristics of the studies. Overall, 71 articles yielding 128 prevalence estimates were included. The pooled prevalence of COVID-19 vaccination acceptance rate was 66% (95% CI: 61-71%). This varied by geographic area, ranging from 36% (95% CI: 18-60%) in Africa to 83% (95% CI: 82-84%) in Oceania, and there was high variability between countries (15.4% Cameroon-100% Bhutan). Meta-regression analysis showed that studies that investigated COVID-19 vaccination intentions using multiple choice/scoring gave a vaccine acceptance prevalence lower than studies with only two possible answers (yes/no) (ß: -1.02 95% CI: -1.41 to -0.63). Despite some variation in the estimates, the results showed that one in three people may refuse/delay COVID-19 vaccination.

Identifiants

pubmed: 36146566
pii: vaccines10091488
doi: 10.3390/vaccines10091488
pmc: PMC9506365
pii:
doi:

Types de publication

Journal Article Review

Langues

eng

Références

Front Public Health. 2021 Aug 06;9:709127
pubmed: 34422750
Mult Scler Relat Disord. 2021 Apr;49:102788
pubmed: 33508570
Int J Environ Res Public Health. 2021 Mar 08;18(5):
pubmed: 33800187
Nat Commun. 2021 Jan 4;12(1):29
pubmed: 33397962
Nat Rev Nephrol. 2022 Jul;18(7):409-410
pubmed: 35414006
Int J Infect Dis. 2021 May;106:52-60
pubmed: 33781902
Postgrad Med J. 2023 Jun 15;99(1172):520-528
pubmed: 37319159
BMC Health Serv Res. 2018 Nov 14;18(1):853
pubmed: 30428886
Eur J Epidemiol. 2020 Aug;35(8):775-779
pubmed: 32785815
Hum Vaccin Immunother. 2021 Jun 3;17(6):1612-1621
pubmed: 33242386
Nat Rev Dis Primers. 2021 Jun 10;7(1):41
pubmed: 34112811
Medicine (Baltimore). 2022 Jul 1;101(26):e29741
pubmed: 35777032
Ann Intern Med. 2020 Dec 15;173(12):964-973
pubmed: 32886525
PLoS One. 2022 May 18;17(5):e0268711
pubmed: 35584110
Int J Clin Pract. 2021 Jul;75(7):e14226
pubmed: 33864328
PLoS Med. 2009 Jul 21;6(7):e1000097
pubmed: 19621072
Vaccine. 2020 Sep 29;38(42):6500-6507
pubmed: 32863069
PLoS One. 2021 Feb 16;16(2):e0246970
pubmed: 33592035
Hum Vaccin Immunother. 2020 Sep 1;16(9):2204-2214
pubmed: 32730103
Vaccine. 2020 Oct 21;38(45):7049-7056
pubmed: 32980199
Vaccines (Basel). 2020 Oct 03;8(4):
pubmed: 33022917
Nat Commun. 2022 Feb 1;13(1):636
pubmed: 35105869
J Gen Intern Med. 2021 Mar;36(3):753-761
pubmed: 33403622
Vaccine. 2020 Dec 3;38(51):8090-8098
pubmed: 33187765
Vaccines (Basel). 2021 Mar 17;9(3):
pubmed: 33802873
Hum Vaccin Immunother. 2022 Dec 31;18(1):1-9
pubmed: 35061972
Front Med (Lausanne). 2022 Jan 27;8:783982
pubmed: 35155467
J Clin Nurs. 2022 Jan;31(1-2):62-86
pubmed: 34227179
BMJ. 2021 Mar 29;372:n71
pubmed: 33782057
Prev Med. 2021 Sep;150:106694
pubmed: 34171345
Vaccines (Basel). 2020 Dec 30;9(1):
pubmed: 33396832
EClinicalMedicine. 2020 Sep;26:100495
pubmed: 32838242
Vaccine. 2021 Feb 12;39(7):1080-1086
pubmed: 33461833
Pharm Pract (Granada). 2021 Jan-Mar;19(1):2317
pubmed: 33828623
Vaccines (Basel). 2021 Mar 22;9(3):
pubmed: 33810131
Nat Med. 2021 Feb;27(2):225-228
pubmed: 33082575
Early Hum Dev. 2020 Oct 1;:105213
pubmed: 33032879
Int J Nurs Stud. 2021 Feb;114:103854
pubmed: 33326864
Psychol Med. 2020 Oct 19;:1-3
pubmed: 33070804
Vaccines (Basel). 2021 Nov 07;9(11):
pubmed: 34835223
Vaccines (Basel). 2021 Mar 24;9(4):
pubmed: 33804808
Vaccine. 2015 Aug 14;33(34):4157-60
pubmed: 25896380
Vaccines (Basel). 2021 Mar 12;9(3):
pubmed: 33808958
Int J Environ Res Public Health. 2022 Apr 07;19(8):
pubmed: 35457297
J Community Health. 2021 Oct;46(5):1013-1019
pubmed: 33835369
Risk Anal. 2023 Jun;43(6):1174-1186
pubmed: 35822654
Influenza Other Respir Viruses. 2021 May;15(3):361-370
pubmed: 33605010
Front Public Health. 2021 Feb 10;9:632914
pubmed: 33643995
Soc Sci Med. 2020 Nov;265:113414
pubmed: 33038683
PLoS One. 2022 Mar 23;17(3):e0265496
pubmed: 35320309
Front Psychol. 2020 Oct 19;11:575950
pubmed: 33192883
Vaccine. 2015 Aug 14;33(34):4161-4
pubmed: 25896383
Hum Vaccin Immunother. 2022 Dec 31;18(1):1950505
pubmed: 34346840
N Engl J Med. 2022 Jul 7;387(1):58-65
pubmed: 35767527
Vaccines (Basel). 2019 Nov 29;7(4):
pubmed: 31795438
Travel Med Infect Dis. 2021 May-Jun;41:102059
pubmed: 33848692
Am J Infect Control. 2021 Oct;49(10):1295-1304
pubmed: 34273461
Hum Vaccin Immunother. 2021 May 4;17(5):1304-1312
pubmed: 33118868
Vaccines (Basel). 2021 Mar 03;9(3):
pubmed: 33802285
Expert Rev Vaccines. 2020 Oct;19(10):899-901
pubmed: 32945213
J Prev Med Hyg. 2019 Mar 29;60(1):E12-E17
pubmed: 31041405
Vaccines (Basel). 2020 Aug 27;8(3):
pubmed: 32867224
Vaccine. 2020 Oct 21;38(45):7002-7006
pubmed: 32988688
Am J Perinatol. 2022 Apr;39(5):492-500
pubmed: 34670322
Qual Quant. 2008 Dec;42(6):779-794
pubmed: 20084107
J Community Health. 2021 Apr;46(2):270-277
pubmed: 33389421
Mayo Clin Proc. 2021 Mar;96(3):699-707
pubmed: 33673921
Vaccines (Basel). 2021 Jun 01;9(6):
pubmed: 34205959
PLoS Negl Trop Dis. 2020 Dec 17;14(12):e0008961
pubmed: 33332359
Front Public Health. 2022 Jun 03;10:869838
pubmed: 35719679
Vaccines (Basel). 2022 Mar 11;10(3):
pubmed: 35335059
Lancet. 2021 Mar 13;397(10278):1023-1034
pubmed: 33587887
Front Med (Lausanne). 2021 Mar 01;8:644300
pubmed: 33732723
Am J Infect Control. 2021 Sep;49(9):1152-1157
pubmed: 33930516
Br J Health Psychol. 2020 Nov;25(4):1039-1054
pubmed: 32889759
Vaccines (Basel). 2021 Feb 19;9(2):
pubmed: 33669659
Mult Scler Relat Disord. 2021 Jun;51:102880
pubmed: 33740481
Lancet Glob Health. 2022 Mar;10(3):e320-e321
pubmed: 34942117
Eur J Epidemiol. 2020 Aug;35(8):781-783
pubmed: 32761440
Int J Clin Pract. 2021 Apr;75(4):e13891
pubmed: 33278857
Rheumatol Int. 2021 Jun;41(6):1105-1114
pubmed: 33779780
Hum Vaccin Immunother. 2019;15(10):2423-2433
pubmed: 30829102
BMJ Open. 2022 Feb 15;12(2):e051775
pubmed: 35168970
J Multidiscip Healthc. 2020 Nov 20;13:1657-1663
pubmed: 33262600
Vaccine. 2015 Aug 14;33(34):4165-75
pubmed: 25896384
Vaccine X. 2022 Aug;11:100164
pubmed: 35573268
Psychol Med. 2022 Jan;52(2):251-263
pubmed: 32436485
Nat Commun. 2022 Jul 1;13(1):3801
pubmed: 35778396
BMJ. 2021 May 20;373:n1138
pubmed: 34016653
Glob Health Res Policy. 2021 Jan 29;6(1):3
pubmed: 33509291
Vaccines (Basel). 2020 Oct 01;8(4):
pubmed: 33019663
Epidemiology. 2020 Sep;31(5):713-717
pubmed: 32657954
Vaccines (Basel). 2021 Feb 18;9(2):
pubmed: 33670661
Pragmat Obs Res. 2020 Oct 29;11:103-109
pubmed: 33154695
BMC Infect Dis. 2022 Feb 14;22(1):153
pubmed: 35164700
Front Public Health. 2015 Nov 26;3:269
pubmed: 26636066
Hum Vaccin Immunother. 2013 Dec;9(12):2643-8
pubmed: 24247148
Infect Control Hosp Epidemiol. 2021 Jun;42(6):775-777
pubmed: 33557977
Data Brief. 2020 Dec;33:106446
pubmed: 33106773
J Hosp Infect. 2021 Feb;108:168-173
pubmed: 33259883
Oncologist. 2017 Oct;22(10):1197-1211
pubmed: 28606972
Vaccines (Basel). 2022 Jan 24;10(2):
pubmed: 35214638
Eur J Health Econ. 2020 Sep;21(7):977-982
pubmed: 32591957
Lancet Reg Health Eur. 2021 Feb;1:100012
pubmed: 33954296
JAMA Netw Open. 2021 Mar 1;4(3):e215344
pubmed: 33755164
Open Forum Infect Dis. 2021 Jan 04;8(2):ofaa658
pubmed: 33623802
Vaccines (Basel). 2021 Feb 18;9(2):
pubmed: 33670621
Viruses. 2021 Feb 26;13(3):
pubmed: 33652829
Postgrad Med J. 2021 Mar;97(1145):143-149
pubmed: 33115909
Psychol Med. 2022 Oct;52(14):3127-3141
pubmed: 33305716
J Am Geriatr Soc. 2021 Mar;69(3):593-599
pubmed: 33370448
Vaccine. 2020 Nov 10;38(48):7585-7586
pubmed: 33121655
Eur J Epidemiol. 2020 Aug;35(8):785-788
pubmed: 32808095
Lancet Public Health. 2021 Apr;6(4):e210-e221
pubmed: 33556325
Vaccines (Basel). 2021 Mar 05;9(3):
pubmed: 33807732
EClinicalMedicine. 2021 Oct;40:101113
pubmed: 34490416
J Med Virol. 2021 Jul;93(7):4280-4291
pubmed: 33644891
Int J Infect Dis. 2021 Mar;104:335-346
pubmed: 33444754
Lancet Infect Dis. 2021 Mar;21(3):318-319
pubmed: 32619436
Vaccine. 2020 Nov 17;38(49):7789-7798
pubmed: 33109389
Lancet Infect Dis. 2021 May;21(5):e110
pubmed: 32941786
BMJ. 2003 Sep 6;327(7414):557-60
pubmed: 12958120

Auteurs

Erika Renzi (E)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Valentina Baccolini (V)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Giuseppe Migliara (G)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Ciro Bellotta (C)

National Hospital A.O.R.N. "Antonio Cardarelli", 80131 Naples, Italy.

Mariateresa Ceparano (M)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Pierluigi Donia (P)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Carolina Marzuillo (C)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Corrado De Vito (C)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Paolo Villari (P)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Azzurra Massimi (A)

Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy.

Classifications MeSH