Yield of the electrophysiological study in patients with new-onset left bundle branch block after transcathether aortic valve replacement: The PR interval matters.

HV interval PR interval atrioventricular block (AV block) electrophysiological study (EPS) trans-catheter aortic valve replacement (TAVR)

Journal

Frontiers in cardiovascular medicine
ISSN: 2297-055X
Titre abrégé: Front Cardiovasc Med
Pays: Switzerland
ID NLM: 101653388

Informations de publication

Date de publication:
2022
Historique:
received: 01 04 2022
accepted: 08 08 2022
entrez: 23 9 2022
pubmed: 24 9 2022
medline: 24 9 2022
Statut: epublish

Résumé

Studies suggest that performing an electrophysiological study (EPS) may be useful to identify patients with new-onset left bundle branch block (LBBB) post-TAVR at risk of atrioventricular block. However, tools to optimize the yield of such strategy are needed. We therefore aimed to investigate whether 12-lead ECG changes post-TAVR may help identify patients with abnormal EPS findings. Consecutive patients with new-onset LBBB post-TAVR who underwent EPS were included. PR and QRS intervals were measured on 12-lead ECG pre-TAVR and during EPS. Abnormal EPS was defined as an HV interval > 55 ms. Among 61 patients, 28 (46%) had an HV interval > 55 ms after TAVR. Post-TAVR PR interval and ΔPR (PR-post-pre-TAVR) were significantly longer in patients with prolonged HV (PR: 188 ± 38 vs. 228 ± 34 ms, PR interval assessment may be useful to select patients with new-onset LBBB after TAVR who may benefit most from an EPS. In patients with PR ≤ 200 ms

Sections du résumé

Background UNASSIGNED
Studies suggest that performing an electrophysiological study (EPS) may be useful to identify patients with new-onset left bundle branch block (LBBB) post-TAVR at risk of atrioventricular block. However, tools to optimize the yield of such strategy are needed. We therefore aimed to investigate whether 12-lead ECG changes post-TAVR may help identify patients with abnormal EPS findings.
Materials and methods UNASSIGNED
Consecutive patients with new-onset LBBB post-TAVR who underwent EPS were included. PR and QRS intervals were measured on 12-lead ECG pre-TAVR and during EPS. Abnormal EPS was defined as an HV interval > 55 ms.
Results UNASSIGNED
Among 61 patients, 28 (46%) had an HV interval > 55 ms after TAVR. Post-TAVR PR interval and ΔPR (PR-post-pre-TAVR) were significantly longer in patients with prolonged HV (PR: 188 ± 38 vs. 228 ± 34 ms,
Conclusion UNASSIGNED
PR interval assessment may be useful to select patients with new-onset LBBB after TAVR who may benefit most from an EPS. In patients with PR ≤ 200 ms

Identifiants

pubmed: 36148076
doi: 10.3389/fcvm.2022.910693
pmc: PMC9485718
doi:

Types de publication

Journal Article

Langues

eng

Pagination

910693

Commentaires et corrections

Type : ErratumIn

Informations de copyright

Copyright © 2022 Pagnoni, Meier, Luca, Fournier, Aminfar, Gentil, Haddad, Domenichini, Lebloa, Herrera-Siklody, Cook, Goy, Roguelov, Girod, Rubimbura, Dupré, Eeckhout, Pruvot, Muller and Pascale.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

Références

N Engl J Med. 2019 Aug 15;381(7):685
pubmed: 31412190
Eur Heart J. 2017 Sep 21;38(36):2739-2791
pubmed: 28886619
J Am Coll Cardiol. 2015 Feb 10;65(5):437-48
pubmed: 25660921
J Electrocardiol. 2020 Mar - Apr;59:68-73
pubmed: 32007908
JACC Cardiovasc Interv. 2018 Aug 13;11(15):1509-1518
pubmed: 30093055
J Am Coll Cardiol. 2019 Aug 27;74(8):1086-1106
pubmed: 31439219
BMC Cardiovasc Disord. 2012 Oct 04;12:87
pubmed: 23035864
Eur Heart J. 2021 Sep 14;42(35):3427-3520
pubmed: 34455430
JACC Cardiovasc Interv. 2018 Aug 13;11(15):1519-1526
pubmed: 30093056
JACC Cardiovasc Interv. 2016 Jun 27;9(12):1269-1276
pubmed: 27339844
Cardiovasc Revasc Med. 2017 Jul - Aug;18(5S1):S10-S13
pubmed: 28377313
Am J Cardiol. 2018 Jun 1;121(11):1351-1357
pubmed: 29598854
Circulation. 1973 May;47(5):1133-4
pubmed: 4705576
Europace. 2016 Jan;18(1):131-7
pubmed: 26060209
Heart Rhythm. 2015 Feb;12(2):321-9
pubmed: 25446155
Arrhythm Electrophysiol Rev. 2020 Jun 3;9(1):20-27
pubmed: 32637116
J Am Heart Assoc. 2020 Mar 3;9(5):e014446
pubmed: 32089049
Circulation. 2009 Mar 17;119(10):e235-40
pubmed: 19228822
J Interv Card Electrophysiol. 2017 Mar;48(2):121-130
pubmed: 27987072
Am J Cardiol. 2020 Mar 1;125(5):795-802
pubmed: 31889524
Int J Cardiol. 2017 Jun 1;236:216-220
pubmed: 28237734

Auteurs

Mattia Pagnoni (M)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

David Meier (D)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Adrian Luca (A)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Stephane Fournier (S)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.
Division of Cardiology, Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.

Farhang Aminfar (F)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Pascale Gentil (P)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Christelle Haddad (C)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.
Arrhythmias Unit, Louis Pradel Cardiovascular Hospital, Hospices Civils de Lyon, Lyon, France.

Giulia Domenichini (G)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Mathieu Lebloa (M)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Claudia Herrera-Siklody (C)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Stephane Cook (S)

Department of Cardiology, Clinique Cecil Hirslanden Group, Lausanne, Switzerland.
Department of Cardiology, University Hospital Fribourg, Fribourg, Switzerland.

Jean-Jacques Goy (JJ)

Department of Cardiology, Clinique Cecil Hirslanden Group, Lausanne, Switzerland.
Department of Cardiology, University Hospital Fribourg, Fribourg, Switzerland.

Christan Roguelov (C)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Grégoire Girod (G)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Vladimir Rubimbura (V)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Marion Dupré (M)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Eric Eeckhout (E)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Etienne Pruvot (E)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Olivier Muller (O)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Patrizio Pascale (P)

Department of Cardiology, Lausanne University Hospital, Lausanne, Switzerland.

Classifications MeSH