Surgery for mesenchymal neoplasms of the esophagus: experience over 2 decades from a tertiary healthcare center in India.
Enucleation
Esophagectomy
Esophagus
Experience
Leiomyomas
Mesenchymal tumor
Journal
Updates in surgery
ISSN: 2038-3312
Titre abrégé: Updates Surg
Pays: Italy
ID NLM: 101539818
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
13
07
2022
accepted:
29
08
2022
pubmed:
24
9
2022
medline:
23
11
2022
entrez:
23
9
2022
Statut:
ppublish
Résumé
Mesenchymal tumors are the most common benign neoplasms of the esophagus. Owing to the rarity of these neoplasms, there is a dearth of literature regarding their diagnosis and management. Our 2-decade-long experience in managing these neoplasms surgically is presented. Relevant clinical data of all patients with esophageal mesenchymal neoplasms (EMNs) managed between January 2000 and May 2020 were retrospectively collected from a prospectively maintained esophageal diseases database in the Department of GI Surgery, AIIMS, New Delhi (India). Special emphasis was given to data pertaining to diagnostic evaluation of patients, type of surgery done (enucleation vs. resection), postoperative outcomes, histopathology and long-term follow-up. Nineteen patients (12 females; age 15-66 years) underwent surgery for EMN (mean tumor size 7.6 cm; enucleation 10; resection 9). On histopathological examination, 17 cases were noted to be benign esophageal leiomyomas and 2 were identified as gastrointestinal stromal tumors. There was no perioperative mortality. All cases were followed up for a median duration of 6 years (range 1-19 years) with no evidence of recurrence in any case. Though EMNs are uncommon, they are mostly benign, and the long-term outcomes after surgical excision are gratifying.
Identifiants
pubmed: 36149582
doi: 10.1007/s13304-022-01373-8
pii: 10.1007/s13304-022-01373-8
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1889-1899Informations de copyright
© 2022. Italian Society of Surgery (SIC).
Références
Miettinen M, Sarlomo-Rikala M, Sobin LH, Lasota J (2000) Esophageal stromal tumors: a clinicopathologic, immunohistochemical, and molecular genetic study of 17 cases and comparison with esophageal leiomyomas and leiomyosarcomas. Am J Surg Pathol 24:211–222. https://doi.org/10.1097/00000478-200002000-00007
doi: 10.1097/00000478-200002000-00007
pubmed: 10680889
Punpale A, Rangole A, Bhambhani N et al (2007) Leiomyoma of esophagus. Ann Thorac Cardiovasc Surg 13:78–81
pubmed: 17505413
Hatch GF, Wertheimer-Hatch L, Hatch KF et al (2000) Tumors of the esophagus. World J Surg 24:401–411. https://doi.org/10.1007/s002689910065
doi: 10.1007/s002689910065
pubmed: 10706912
Postlethwait RW, Wendell Musser A (1974) Changes in the esophagus in 1000 autopsy specimens. J Thorac Cardiovasc Surg 68:953–956. https://doi.org/10.1016/s0022-5223(19)39690-4
doi: 10.1016/s0022-5223(19)39690-4
pubmed: 4420581
Clavien PA, Strasberg SM (2009) Severity grading of surgical complications. Ann Surg 250:197–198
doi: 10.1097/SLA.0b013e3181b6dcab
pubmed: 19638901
Giovanna M-B, José-Alberto M-H (2012) Esophageal leiomyoma: experience with nine surgical patients. Acta méd. costarric [Internet]
MG Seremetis WLVGJP (1976) Leiomyomata of the esophagus: an analysis of 838 cases. Cancer 38:2166–2177. https://doi.org/10.1002/1097-0142(197611)38:5%3c2166::aid-cncr2820380547%3e3.0.co
doi: 10.1002/1097-0142(197611)38:5<2166::aid-cncr2820380547>3.0.co
Lee LS, Singhal S, Brinster CJ et al (2004) Current management of esophageal leiomyoma. J Am Coll Surg 198:136–146. https://doi.org/10.1016/j.jamcollsurg.2003.08.015
doi: 10.1016/j.jamcollsurg.2003.08.015
pubmed: 14698321
Sun X, Wang J, Yang G (2012) Surgical treatment of esophageal leiomyoma larger than 5 cm in diameter: a case report and review of the literature. J Thorac Dis 4:323–326. https://doi.org/10.3978/j.issn.2072-1439.2011.11.02
doi: 10.3978/j.issn.2072-1439.2011.11.02
pubmed: 22754674
pmcid: 3378205
Levine MS, Buck JL, Pantongrag-Brown L et al (1996) Esophageal leiomyomatosis. Radiology 199:533–536. https://doi.org/10.1148/radiology.199.2.8668807
doi: 10.1148/radiology.199.2.8668807
pubmed: 8668807
Faulx AL, Kothari S, Acosta RD et al (2017) The role of endoscopy in subepithelial lesions of the GI tract Prepared by: standards of practice committee. Gastrointest Endosc 85:1117–1132. https://doi.org/10.1016/j.gie.2017.02.022
doi: 10.1016/j.gie.2017.02.022
pubmed: 28385194
Choi SH, Kim YT, Han KN et al (2011) Surgical management of the esophageal leiomyoma: lessons from a retrospective review. Dis Esophagus 24:325–329. https://doi.org/10.1111/j.1442-2050.2010.01144.x
doi: 10.1111/j.1442-2050.2010.01144.x
pubmed: 21143693
Xu G-Q, Qian J-J, Chen M-H et al (2012) Endoscopic ultrasonography for the diagnosis and selecting treatment of esophageal leiomyoma. J Gastroenterol Hepatol 27:521–525. https://doi.org/10.1111/j.1440-1746.2011.06929.x
doi: 10.1111/j.1440-1746.2011.06929.x
pubmed: 21916996
Massari M, De Simone M, Cioffi U, Gabrielli F, Boccasanta P, Bonavina L (1998) Endoscopic ultrasonography in the evaluation of leiomyoma and extramucosal cysts of the esophagus. Hepatogastroenterology 45(22):938–943
pubmed: 9755985
Megibow AJ, Balthazar EJ, Hulnick DH et al (1985) CT evaluation of gastrointestinal leiomyomas and leiomyosarcomas. Am J Roentgenol 144:727–731. https://doi.org/10.2214/ajr.144.4.727
doi: 10.2214/ajr.144.4.727
Lewis RB, Mehrotra AK, Rodriguez P, Levine MS (2013) From the radiologic pathology archives: esophageal neoplasms: radiologic-pathologic correlation. Radiographics 33:1083–1108. https://doi.org/10.1148/rg.334135027
doi: 10.1148/rg.334135027
pubmed: 23842973
Yang PS, Lee KS, Lee SJ et al (2001) Esophageal leiomyoma: radiologic findings in 12 patients. Korean J Radiol 2:132–137. https://doi.org/10.3348/kjr.2001.2.3.132
doi: 10.3348/kjr.2001.2.3.132
pubmed: 11752983
pmcid: 2718110
Choi YR, Kim SH, Kim SA et al (2014) Differentiation of large (≥5 cm) gastrointestinal stromal tumors from benign subepithelial tumors in the stomach: Radiologists’ performance using CT. Eur J Radiol 83:250–260. https://doi.org/10.1016/j.ejrad.2013.10.028
doi: 10.1016/j.ejrad.2013.10.028
pubmed: 24325848
Bonavina L, Segalin A, Rosati R et al (1995) Surgical therapy of esophageal leiomyoma. J Am Coll Surg 181:257–262
pubmed: 7670685
von Rahden BHA, Stein HJ, Feussner H, Siewert JR (2004) Enucleation of submucosal tumors of the esophagus: minimally invasive versus open approach. Surg Endosc 18:924–930. https://doi.org/10.1007/s00464-003-9130-9
doi: 10.1007/s00464-003-9130-9
Bardini R, Segalin A, Ruol A et al (1992) Videothoracoscopic enucleation of esophageal leiomyoma. Ann Thorac Surg 54:576–577. https://doi.org/10.1016/0003-4975(92)90463-E
doi: 10.1016/0003-4975(92)90463-E
pubmed: 1510534
Izumi Y, Inoue H, Endo M (1996) Combined endoluminal-intracavitary thoracoscopic enucleation of leiomyoma of the esophagus: a new method. Surg Endosc 10:457–458. https://doi.org/10.1007/BF00191641
doi: 10.1007/BF00191641
pubmed: 8661804
Laurent M, Brahmi M, Dufresne A et al (2019) Adjuvant therapy with imatinib in gastrointestinal stromal tumors (GISTs)—review and perspectives. Transl Gastroenterol Hepatol. https://doi.org/10.21037/tgh.2019.03.07
doi: 10.21037/tgh.2019.03.07
pubmed: 31143845
pmcid: 6509420
Mutrie CJ, Donahue DM, Wain JC, et al (2005) Esophageal leiomyoma: a 40-year experience. Ann Thorac Surg 79:1122–1125. https://doi.org/10.1016/j.athoracsur.2004.08.029
doi: 10.1016/j.athoracsur.2004.08.029
pubmed: 15797036
Zaninotto G, Portale G, Costantini M, et al (2006) Minimally invasive enucleation of esophageal leiomyoma. Surg Endosc 20:1904–1908. https://doi.org/10.1007/s00464-005-0838-6
doi: 10.1007/s00464-005-0838-6
pubmed: 16960671
Vallböhmer D, Hölscher AH, Brabender J, et al (2007) Thoracoscopic enucleation of esophageal leiomyomas: a feasible and safe procedure. Endoscopy 39:1097–1099. https://doi.org/10.1055/s-2007-966928
doi: 10.1055/s-2007-966928
pubmed: 18072062
Jiang W, Rice TW, Goldblum JR (2013) Esophageal leiomyoma: experience from a single institution. Dis Esophagus 26:167–174. https://doi.org/10.1111/j.1442-2050.2012.01345.x
doi: 10.1111/j.1442-2050.2012.01345.x
pubmed: 22458777
Ben-David K, Alvarez J, Rossidis G, et al (2015) Thoracoscopic and Laparoscopic Enucleation of Esophageal Leiomyomas. J Gastrointest Surg 19:1350–1354. https://doi.org/10.1007/s11605-015-2817-0
doi: 10.1007/s11605-015-2817-0
pubmed: 25868871
Milito P, Asti E, Aiolfi A et al (2020) Clinical Outcomes of Minimally Invasive Enucleation of Leiomyoma of the Esophagus and Esophagogastric Junction. J Gastrointest Surg 24:499–504. https://doi.org/10.1007/s11605-019-04210-3
doi: 10.1007/s11605-019-04210-3
pubmed: 30941689