Surgical Rib Fixation in Obese Patients with Isolated Flail Chest Improves Outcomes: A Matched Cohort Study.


Journal

World journal of surgery
ISSN: 1432-2323
Titre abrégé: World J Surg
Pays: United States
ID NLM: 7704052

Informations de publication

Date de publication:
12 2022
Historique:
accepted: 10 09 2022
pubmed: 24 9 2022
medline: 9 11 2022
entrez: 23 9 2022
Statut: ppublish

Résumé

Obesity is associated with adverse outcomes after major operations. The role of operative rib fixation (RF) in obese patients with flail chest is not clear. The presence of other associated injuries may complicate the interpretation of outcomes. This study compared outcomes after RF to nonoperative management (NOM) in obese patients with isolated flail chest injury. Adult obese patients (BMI > 29.9) with flail chest were identified from the Trauma Quality Improvement Program (TQIP) database (2016-2018). Hospital transfers, death within 72 h, and extrathoracic injuries were excluded. RF patients were propensity score matched (1:2) to similar NOM patients. Multivariate regression identified independent factors predicting adverse outcomes. Overall, 367 patients with isolated flail chest who underwent RF were matched with 734 in the NOM group. After matching, the mortality rate was significantly lower in the RF group (1.4% vs. 3.7%; p < 0.05). RF had longer HLOS (15.7 days vs. 12.8 days; p < 0.05) and ICU LOS (10.1 days vs. 8.6 days; p < 0.05), shorter ventilator days (9.2 days vs. 11.5 days; p < 0.05), and a higher rate of venous thromboembolism (7.1% vs. 3.5%, p < 0.05). On multivariate analysis, RF was associated with decreased mortality (OR 0.27; p < 0.05). Early RF (≤ 72 h) was associated with shorter ICU stay and mechanical ventilation. RF for isolated flail chest in obese patients is associated with decreased mortality and fewer ventilator days. When performed early, fixation decreases the need for prolonged ventilator use and ICU stay. A more aggressive VTE prophylaxis should be considered in patients undergoing RF.

Sections du résumé

BACKGROUND
Obesity is associated with adverse outcomes after major operations. The role of operative rib fixation (RF) in obese patients with flail chest is not clear. The presence of other associated injuries may complicate the interpretation of outcomes. This study compared outcomes after RF to nonoperative management (NOM) in obese patients with isolated flail chest injury.
METHODS
Adult obese patients (BMI > 29.9) with flail chest were identified from the Trauma Quality Improvement Program (TQIP) database (2016-2018). Hospital transfers, death within 72 h, and extrathoracic injuries were excluded. RF patients were propensity score matched (1:2) to similar NOM patients. Multivariate regression identified independent factors predicting adverse outcomes.
RESULTS
Overall, 367 patients with isolated flail chest who underwent RF were matched with 734 in the NOM group. After matching, the mortality rate was significantly lower in the RF group (1.4% vs. 3.7%; p < 0.05). RF had longer HLOS (15.7 days vs. 12.8 days; p < 0.05) and ICU LOS (10.1 days vs. 8.6 days; p < 0.05), shorter ventilator days (9.2 days vs. 11.5 days; p < 0.05), and a higher rate of venous thromboembolism (7.1% vs. 3.5%, p < 0.05). On multivariate analysis, RF was associated with decreased mortality (OR 0.27; p < 0.05). Early RF (≤ 72 h) was associated with shorter ICU stay and mechanical ventilation.
CONCLUSION
RF for isolated flail chest in obese patients is associated with decreased mortality and fewer ventilator days. When performed early, fixation decreases the need for prolonged ventilator use and ICU stay. A more aggressive VTE prophylaxis should be considered in patients undergoing RF.

Identifiants

pubmed: 36151336
doi: 10.1007/s00268-022-06748-x
pii: 10.1007/s00268-022-06748-x
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

2890-2899

Informations de copyright

© 2022. The Author(s) under exclusive licence to Société Internationale de Chirurgie.

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Auteurs

Joshua Dilday (J)

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, 2051, Marengo St, Inpatient Tower, C5L100, Los Angeles, CA, 90033, USA.

Chih Ying Chien (CY)

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, 2051, Marengo St, Inpatient Tower, C5L100, Los Angeles, CA, 90033, USA.
Department of General Surgery, Chang Gung Memorial Hospital, Keelung, Taiwan.

Meghan Lewis (M)

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, 2051, Marengo St, Inpatient Tower, C5L100, Los Angeles, CA, 90033, USA.

Brent Emigh (B)

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, 2051, Marengo St, Inpatient Tower, C5L100, Los Angeles, CA, 90033, USA.

Elizabeth R Benjamin (ER)

Division of Trauma and Surgical Critical Care, Grady Memorial Hospital, Atlanta, Georgia.

Demetrios Demetriades (D)

Division of Trauma and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, 2051, Marengo St, Inpatient Tower, C5L100, Los Angeles, CA, 90033, USA. demetria@usc.edu.

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