Pain Management After Open Liver Resection: Epidural Analgesia Versus Ultrasound-Guided Erector Spinae Plane Block.

erector spinae plane block liver resection postoperative pain regional analgesia thoracic epidural anesthesia

Journal

Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737

Informations de publication

Date de publication:
Aug 2022
Historique:
accepted: 14 08 2022
entrez: 26 9 2022
pubmed: 27 9 2022
medline: 27 9 2022
Statut: epublish

Résumé

Multimodal analgesia techniques, including regional analgesia, have been shown to provide effective analgesia and minimize opioid consumption after liver resection surgery. While thoracic epidural analgesia (TEA) is considered the gold standard, its role in the current era of enhanced recovery after surgery (ERAS) has been questioned. Erector spinae plane blocks (ESPBs) have the potential to provide effective postoperative analgesia without the risks associated with epidural analgesia. The primary aim of this quality improvement project was to evaluate the analgesic efficacy of ultrasound-guided ESPB in comparison with TEA in patients undergoing open liver resection. Fifty patients who underwent open liver resection and received TEA (n=25) or ESPB (n=25) as part of an ERAS pathway were retrospectively identified. The primary outcome measure was cumulative postoperative opioid consumption at 24 hours. Secondary outcomes included opioid consumption, pain scores, the incidence of nausea and vomiting requiring antiemetics, lower extremity muscle weakness, and occurrence of hypotension requiring treatment on arrival to the post-anesthesia care unit and at 2, 6, 12, 24 hours, and daily through postoperative day 7.  Results: Opioid requirements were significantly lower in the TEA group compared to the ESPB group. Postoperative pain scores at rest and with deep inspiration were significantly lower in the TEA group through postoperative day 5. There were no differences in other outcome measures. These findings suggest that compared with ESPB, TEA provides superior pain relief after open liver resection.

Sections du résumé

BACKGROUND BACKGROUND
Multimodal analgesia techniques, including regional analgesia, have been shown to provide effective analgesia and minimize opioid consumption after liver resection surgery. While thoracic epidural analgesia (TEA) is considered the gold standard, its role in the current era of enhanced recovery after surgery (ERAS) has been questioned. Erector spinae plane blocks (ESPBs) have the potential to provide effective postoperative analgesia without the risks associated with epidural analgesia. The primary aim of this quality improvement project was to evaluate the analgesic efficacy of ultrasound-guided ESPB in comparison with TEA in patients undergoing open liver resection.
METHODS METHODS
Fifty patients who underwent open liver resection and received TEA (n=25) or ESPB (n=25) as part of an ERAS pathway were retrospectively identified. The primary outcome measure was cumulative postoperative opioid consumption at 24 hours. Secondary outcomes included opioid consumption, pain scores, the incidence of nausea and vomiting requiring antiemetics, lower extremity muscle weakness, and occurrence of hypotension requiring treatment on arrival to the post-anesthesia care unit and at 2, 6, 12, 24 hours, and daily through postoperative day 7.  Results: Opioid requirements were significantly lower in the TEA group compared to the ESPB group. Postoperative pain scores at rest and with deep inspiration were significantly lower in the TEA group through postoperative day 5. There were no differences in other outcome measures.
CONCLUSIONS CONCLUSIONS
These findings suggest that compared with ESPB, TEA provides superior pain relief after open liver resection.

Identifiants

pubmed: 36158398
doi: 10.7759/cureus.28185
pmc: PMC9491619
doi:

Types de publication

Journal Article

Langues

eng

Pagination

e28185

Informations de copyright

Copyright © 2022, Stewart et al.

Déclaration de conflit d'intérêts

The authors have declared financial relationships, which are detailed in the next section.

Références

Best Pract Res Clin Anaesthesiol. 2019 Sep;33(3):259-267
pubmed: 31785712
Pharmacoepidemiol Drug Saf. 2016 Jun;25(6):733-7
pubmed: 26693665
Ann Transl Med. 2017 Sep;5(17):341
pubmed: 28936435
Best Pract Res Clin Anaesthesiol. 2019 Sep;33(3):303-315
pubmed: 31785716
Plast Reconstr Surg Glob Open. 2019 Nov 20;7(11):e2525
pubmed: 31942313
Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7
pubmed: 27501016
Eur J Anaesthesiol. 2021 Aug 1;38(Suppl 2):S106-S112
pubmed: 33653982
Reg Anesth Pain Med. 2021 May;46(5):433-445
pubmed: 33436442
BMC Anesthesiol. 2020 May 1;20(1):99
pubmed: 32357842
J Clin Med. 2021 Aug 18;10(16):
pubmed: 34441958
J Pain Res. 2020 Jul 01;13:1611-1619
pubmed: 32669870
Anaesthesia. 2017 Apr;72(4):452-460
pubmed: 28188621
Korean J Anesthesiol. 2019 Apr;72(2):119-129
pubmed: 30841029
Br J Anaesth. 2016 Sep;117(3):297-308
pubmed: 27543524
Anesth Analg. 2021 Nov 1;133(5):1296-1302
pubmed: 34473654
Anaesthesia. 2022 Mar;77(3):252-256
pubmed: 34751945
A A Pract. 2019 Nov 1;13(9):332-334
pubmed: 31361665
J Surg Res. 2021 Jul;263:124-129
pubmed: 33652174

Auteurs

Jesse W Stewart (JW)

Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, USA.

Adam Yopp (A)

Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA.

Matthew R Porembka (MR)

Division of Surgical Oncology, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA.

John D Karalis (JD)

Department of Surgery, University of Texas Southwestern Medical Center, Dallas, USA.

Mary Sunna (M)

Department of Nursing, Parkland Health and Hospital System, Dallas, USA.

Cedar Schulz (C)

Department of Nursing, Parkland Health and Hospital System, Dallas, USA.

John C Alexander (JC)

Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, USA.

Irina Gasanova (I)

Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, USA.

Girish P Joshi (GP)

Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center, Dallas, USA.

Classifications MeSH