Oolonghomobisflavans exert neuroprotective activities in cultured neuronal cells and anti-aging effects in

anti-aging antioxidants neurite outgrowth neuroprotective oolonghomobisflavans oxidative stress

Journal

Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824

Informations de publication

Date de publication:
2022
Historique:
received: 12 06 2022
accepted: 22 08 2022
entrez: 26 9 2022
pubmed: 27 9 2022
medline: 27 9 2022
Statut: epublish

Résumé

Potential health benefits of tea has attracted significant scientific and public attention worldwide. Tea polyphenols are considered as natural promising complementary therapeutical agents for neurodegenerative diseases. However, the anti-neurodegeneration or anti-aging activities of oolong tea polyphenols have not been investigated. The current study aims to document beneficial effects of oolong tea polyphenols [dimers of epigallocatechin gallate (EGCG), oolonghomobisflavan A (OFA), and oolonghomobisflavan B (OFB)] with neuroprotective and neuritogenesis properties in cultured neuronal (Neuro-2a and HT22) cells and

Identifiants

pubmed: 36158534
doi: 10.3389/fnagi.2022.967316
pmc: PMC9490402
doi:

Types de publication

Journal Article

Langues

eng

Pagination

967316

Informations de copyright

Copyright © 2022 Zhang, Duangjan, Tencomnao, Wu, Wink and Lin.

Déclaration de conflit d'intérêts

MW was an editor for the Frontiers journal. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Shaoxiong Zhang (S)

College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, China.
Natural Products for Neuroprotection and Anti-Ageing Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand.
Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.

Chatrawee Duangjan (C)

Natural Products for Neuroprotection and Anti-Ageing Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand.
Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.
Leonard Davis School of Gerontology, University of Southern California, Los Angeles, Los Angeles, CA, United States.

Tewin Tencomnao (T)

Natural Products for Neuroprotection and Anti-Ageing Research Unit, Department of Clinical Chemistry, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, Thailand.

Liangyu Wu (L)

College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, China.

Michael Wink (M)

Institute of Pharmacy and Molecular Biotechnology, Heidelberg University, Heidelberg, Germany.

Jinke Lin (J)

College of Horticulture, Fujian Agriculture and Forestry University, Fuzhou, China.
Anxi College of Tea Science, Fujian Agriculture and Forestry University, Fuzhou, China.

Classifications MeSH