Primary progressive aphasia and motor neuron disease: A review.

amyotrophic lateral sclerosis frontotemporal degeneration language motor neuron disease primary progressive aphasia

Journal

Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824

Informations de publication

Date de publication:
2022
Historique:
received: 26 07 2022
accepted: 24 08 2022
entrez: 26 9 2022
pubmed: 27 9 2022
medline: 27 9 2022
Statut: epublish

Résumé

This study aims at reviewing, within the framework of motor neuron disease-frontotemporal degeneration (MND-FTD)- This review was pre-registered (osf.io/ds8m4) and performed in accordance with the 2020 PRISMA guidelines. Case reports/series and group studies were included if addressing (1) progressive non-fluent aphasia (PNFA) or semantic dementia (SD) with MND or (2) MND patients with co-morbid PNFA/SD. Out of 546 initial records, 56 studies were included. As to case reports/series ( Insights herewith delivered into the clinical, neuropathological and genetic features of PPA-MND patients prompt further investigations aimed at improving clinical practice within the MND-FTD

Sections du résumé

Background UNASSIGNED
This study aims at reviewing, within the framework of motor neuron disease-frontotemporal degeneration (MND-FTD)-
Methods UNASSIGNED
This review was pre-registered (osf.io/ds8m4) and performed in accordance with the 2020 PRISMA guidelines. Case reports/series and group studies were included if addressing (1) progressive non-fluent aphasia (PNFA) or semantic dementia (SD) with MND or (2) MND patients with co-morbid PNFA/SD.
Results UNASSIGNED
Out of 546 initial records, 56 studies were included. As to case reports/series (
Discussion UNASSIGNED
Insights herewith delivered into the clinical, neuropathological and genetic features of PPA-MND patients prompt further investigations aimed at improving clinical practice within the MND-FTD

Identifiants

pubmed: 36158556
doi: 10.3389/fnagi.2022.1003792
pmc: PMC9492890
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1003792

Informations de copyright

Copyright © 2022 Aiello, Feroldi, De Luca, Guidotti, Arrigoni, Appollonio, Solca, Carelli, Poletti, Verde, Silani and Ticozzi.

Déclaration de conflit d'intérêts

VS received compensation for consulting services and/or speaking activities from AveXis, Cytokinetics, Italfarmaco, Liquidweb S.r.l., and Novartis Pharma AG, receives or has received research supports from the Italian Ministry of Health, AriSLA, and E-Rare Joint Transnational Call. He was in the Editorial Board of Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, European Neurology, American Journal of Neurodegenerative Diseases, Frontiers in Neurology. BP received compensation for consulting services and/or speaking activities from Liquidweb S.r.l. She was Associate Editor for Frontiers in Neuroscience. NT received compensation for consulting services from Amylyx Pharmaceuticals and Zambon Biotech SA. He was Associate Editor for Frontiers in Aging Neuroscience. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Edoardo Nicolò Aiello (EN)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Ph.D. Program in Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Sarah Feroldi (S)

Ph.D. Program in Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Giulia De Luca (G)

Department of Brain and Behavioral Sciences, University of Pavia, Pavia, Italy.

Lucilla Guidotti (L)

Department of Psychology, University of Milano-Bicocca, Milan, Italy.

Eleonora Arrigoni (E)

Ph.D. Program in Neuroscience, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Ildebrando Appollonio (I)

Neurology Section, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Federica Solca (F)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.

Laura Carelli (L)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.

Barbara Poletti (B)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.

Federico Verde (F)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Department of Pathophysiology and Transplantation, "Dino Ferrari" Center, Università degli Studi di Milano, Milan, Italy.

Vincenzo Silani (V)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Department of Pathophysiology and Transplantation, "Dino Ferrari" Center, Università degli Studi di Milano, Milan, Italy.

Nicola Ticozzi (N)

Department of Neurology and Laboratory of Neuroscience, IRCCS Istituto Auxologico Italiano, Milan, Italy.
Department of Pathophysiology and Transplantation, "Dino Ferrari" Center, Università degli Studi di Milano, Milan, Italy.

Classifications MeSH