Dysregulation of dopamine neurotransmission in the nucleus accumbens in immobilization-induced hypersensitivity.

D2-like receptor hyperalgesia microdialysis postsynaptic rat

Journal

Frontiers in pharmacology
ISSN: 1663-9812
Titre abrégé: Front Pharmacol
Pays: Switzerland
ID NLM: 101548923

Informations de publication

Date de publication:
2022
Historique:
received: 07 07 2022
accepted: 26 08 2022
entrez: 26 9 2022
pubmed: 27 9 2022
medline: 27 9 2022
Statut: epublish

Résumé

Cast immobilization causes sensory hypersensitivity, which is also a symptom of neuropathic pain and chronic pain. However, the mechanisms underlying immobilization-induced hypersensitivity remain unclear. The present study investigated the role of dopamine neurotransmission in the nucleus accumbens shell (NAcSh) of rats with cast immobilization-induced mechanical hypersensitivity using

Identifiants

pubmed: 36160381
doi: 10.3389/fphar.2022.988178
pii: 988178
pmc: PMC9493457
doi:

Types de publication

Journal Article

Langues

eng

Pagination

988178

Informations de copyright

Copyright © 2022 Kishikawa, Kawahara, Ohnishi, Sotogaku, Koeda, Kawahara and Nishi.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Yuki Kishikawa (Y)

Department of Rehabilitation Sciences, Faculty of Rehabilitation Sciences, Nishikyushu University, Kanzaki, Japan.
Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.

Yukie Kawahara (Y)

Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.

Yoshinori N Ohnishi (YN)

Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.

Naoki Sotogaku (N)

Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.

Tomoko Koeda (T)

Department of Physical Therapy, Faculty of Rehabilitation Sciences, Nagoya Gakuin University, Nagoya, Japan.

Hiroshi Kawahara (H)

Department of Dental Anesthesiology, Tsurumi University School of Dental Medicine, Yokohama, Japan.

Akinori Nishi (A)

Department of Pharmacology, Kurume University School of Medicine, Kurume, Japan.

Classifications MeSH