Photobiomodulation at 830 nm Stimulates Migration, Survival and Proliferation of Fibroblast Cells.

NIR light diabetic wound hyperglycemia photobiomodulation wound healing

Journal

Diabetes, metabolic syndrome and obesity : targets and therapy

ISSN: 1178-7007

Titre abrégé: Diabetes Metab Syndr Obes

Pays: New Zealand

ID NLM: 101515585

Informations de publication

Date de publication:
2022

Historique:

received: 21 05 2022

accepted: 02 08 2022

entrez: 29 9 2022

pubmed: 30 9 2022

medline: 30 9 2022

Statut: epublish

Résumé

Photobiomodulation (PBM) promotes diabetic wound healing by favoring cell survival and proliferation. This study aimed to investigate the potential of PBM in stimulating cellular migration, viability, and proliferation using the transforming growth factor-β1 (TGF-β1)/Smad signaling pathway. The study explored the in vitro effects of near infrared (NIR) light on cell viability (survival) and proliferation as well as the presence of TGF-β1, phosphorylated TGF-β receptor type I (pTGF-βR1) and phosphorylated mothers against decapentaplegic-homolog (Smad)-2/3 (p-Smad2/3) in different fibroblast cell models. Results show a significant increase in cellular migration in wounded models, and increased viability and proliferation in irradiated cells compared to their respective controls. An increase in the presence of TGF-β1 in the culture media, a reduction in pTGF-βR1 and a slight presence of p-Smad2/3 was observed in the cells. These findings show that PBM at 830 nm using a fluence of 5 J/cm

Identifiants

DOI: 10.2147/DMSO.S374649 PMID: 36172056 PMC: PMC9510698

pubmed: 36172056

doi: 10.2147/DMSO.S374649

pii: 374649

pmc: PMC9510698

doi:

Types de publication

Journal Article

Langues

eng

Pagination

2885-2900

Informations de copyright

Déclaration de conflit d'intérêts

The authors report no conflicts of interest in this work.

Références

Microbes Infect. 1999 Dec;1(15):1349-65

pubmed: 10611762

J Wound Care. 2019 Mar 2;28(Sup3b):s13-s24

pubmed: 30900931

Ann Otol Rhinol Laryngol. 2010 May;119(5):350-7

pubmed: 20524582

Arch Oral Biol. 2003 Feb;48(2):125-32

pubmed: 12642231

Hautarzt. 2020 Nov;71(11):835-842

pubmed: 33044558

Nat Cell Biol. 2008 Sep;10(9):1027-38

pubmed: 19160483

Diabetes Technol Ther. 2007 Oct;9(5):451-9

pubmed: 17931053

BMC Endocr Disord. 2019 Mar 1;19(1):27

pubmed: 30823912

Lasers Surg Med. 2020 Sep;52(7):671-681

pubmed: 31820475

Microb Ecol. 2017 Apr;73(3):710-721

pubmed: 27742997

ScientificWorldJournal. 2014 Jan 06;2014:398412

pubmed: 24511283

J Photochem Photobiol B. 2018 Feb;179:74-83

pubmed: 29353701

Photomed Laser Surg. 2011 Aug;29(8):521-30

pubmed: 21332376

Am J Surg. 1998 Aug;176(2A Suppl):26S-38S

pubmed: 9777970

N Engl J Med. 2017 Jun 15;376(24):2367-2375

pubmed: 28614678

Diabetes Res Clin Pract. 2022 Jan;183:109155

pubmed: 34838640

Lasers Med Sci. 2018 Jul;33(5):1085-1093

pubmed: 29520687

Bone Res. 2018 Jan 31;6:2

pubmed: 29423331

Cell Biochem Funct. 2021 Jul;39(5):596-612

pubmed: 33870502

Lasers Med Sci. 2021 Apr;36(3):555-562

pubmed: 32643032

Cell. 2003 Jun 13;113(6):685-700

pubmed: 12809600

N Engl J Med. 1994 Nov 10;331(19):1286-92

pubmed: 7935686

Lasers Med Sci. 2019 Sep;34(7):1373-1380

pubmed: 30721415

Diabetes Res Clin Pract. 2020 Apr;162:108086

pubmed: 32068099

Med Hypotheses. 2011 Mar;76(3):343-6

pubmed: 21093160

Cold Spring Harb Perspect Biol. 2017 Jan 3;9(1):

pubmed: 27836834

J Investig Dermatol Symp Proc. 2006 Sep;11(1):112-7

pubmed: 17069018

Diabetes Metab Res Rev. 2020 Mar;36 Suppl 1:e3282

pubmed: 32176437

Mar Drugs. 2019 Feb 22;17(2):

pubmed: 30813318

Int J Biol Macromol. 2015 May;76:236-41

pubmed: 25748846

An Bras Dermatol. 2014 Jul-Aug;89(4):616-23

pubmed: 25054749

Cold Spring Harb Perspect Biol. 2017 Mar 1;9(3):

pubmed: 27920040

Adv Ther. 2014 Aug;31(8):817-36

pubmed: 25069580

Lasers Surg Med. 2010 Nov;42(9):656-64

pubmed: 20976805

Exp Cell Res. 2010 Apr 15;316(7):1271-81

pubmed: 20206158

Anim Reprod Sci. 2005 Jul;87(3-4):181-92

pubmed: 15911169

J Lasers Med Sci. 2020 Fall;11(4):491-496

pubmed: 33425303

Wound Repair Regen. 2008 Sep-Oct;16(5):585-601

pubmed: 19128254

Photochem Photobiol. 2011 Nov-Dec;87(6):1433-41

pubmed: 21883243

J Photochem Photobiol B. 2016 Jul;160:53-60

pubmed: 27092999

J Wound Care. 2018 Jul 2;27(7):434-441

pubmed: 30016139

J Invest Dermatol. 2009 Jan;129(1):7-9

pubmed: 19078982

Cell Motil Cytoskeleton. 1997;37(1):33-43

pubmed: 9142437

J Photochem Photobiol B. 2019 Dec;201:111658

pubmed: 31710923

Chin Med. 2019 Sep 18;14:33

pubmed: 31548851

Cell Res. 2009 Jan;19(1):128-39

pubmed: 19114990

Methods Mol Biol. 2020;2109:225-229

pubmed: 31414347

Adv Ther. 2017 Mar;34(3):599-610

pubmed: 28108895

Postgrad Med J. 2009 Jan;85(999):9-14

pubmed: 19240282

Cold Spring Harb Perspect Biol. 2016 May 02;8(5):

pubmed: 27141051

Int J Mol Sci. 2018 Oct 18;19(10):

pubmed: 30340330

Nat Rev Mol Cell Biol. 2013 Aug;14(8):518-28

pubmed: 23877564

Pharmaceuticals (Basel). 2020 Apr 01;13(4):

pubmed: 32244718

Front Endocrinol (Lausanne). 2019 Jul 24;10:499

pubmed: 31396159

J Pediatr Surg. 1988 Jul;23(7):647-52

pubmed: 3204464

Tissue Eng Part A. 2012 Dec;18(23-24):2528-38

pubmed: 22734649

Materials (Basel). 2021 Jun 21;14(12):

pubmed: 34205573

Lasers Med Sci. 2014 Jan;29(1):257-65

pubmed: 23619627

Diabetes Technol Ther. 2010 Dec;12(12):971-8

pubmed: 21128844