Impact of acute schistosomiasis mansoni and long-term ethanol intake on mouse liver pathology.


Journal

Experimental parasitology
ISSN: 1090-2449
Titre abrégé: Exp Parasitol
Pays: United States
ID NLM: 0370713

Informations de publication

Date de publication:
Nov 2022
Historique:
received: 30 04 2022
revised: 08 09 2022
accepted: 21 09 2022
pubmed: 30 9 2022
medline: 27 10 2022
entrez: 29 9 2022
Statut: ppublish

Résumé

While the effect of ethanol and schistosomiasis mansoni on liver injury has been well-documented, the influence of comorbidity on liver pathology remains unclear. To address this gap, schistosomiasis-infected mice were given one daily dose of 18% ethanol for 28 consecutive days, from day 35 post-infection. Mice were assigned to four groups: A. control; B. uninfected/ethanol gavage; C. infected; and D. infected/ethanol gavage. At day 64 post-infection, mice were euthanized by CO

Identifiants

pubmed: 36174706
pii: S0014-4894(22)00182-5
doi: 10.1016/j.exppara.2022.108388
pii:
doi:

Substances chimiques

Ethanol 3K9958V90M
Eosine Yellowish-(YS) TDQ283MPCW
Hematoxylin YKM8PY2Z55
Carbon Dioxide 142M471B3J
Formaldehyde 1HG84L3525

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108388

Informations de copyright

Copyright © 2022. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest We have no conflict of interest to declare.

Auteurs

Luciana Brandão-Bezerra (L)

Romero Lascasas Porto Laboratory of Helminthology, Department of Microbiology, Immunology and Parasitology, Medical Sciences College (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.

Aline Aparecida da Rosa (AAD)

Romero Lascasas Porto Laboratory of Helminthology, Department of Microbiology, Immunology and Parasitology, Medical Sciences College (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.

Regina Maria Figueiredo de Oliveira (RMF)

Romero Lascasas Porto Laboratory of Helminthology, Department of Microbiology, Immunology and Parasitology, Medical Sciences College (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.

Renata Heisler Neves (RH)

Romero Lascasas Porto Laboratory of Helminthology, Department of Microbiology, Immunology and Parasitology, Medical Sciences College (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil.

Christiane Leal Corrêa (CL)

Department of Pathology and Laboratories, Medical Sciences College (FCM), Rio de Janeiro State University (UERJ), Brazil. Medical College, Estácio de Sá University, Rio de Janeiro, Brazil.

José Roberto Machado-Silva (JR)

Romero Lascasas Porto Laboratory of Helminthology, Department of Microbiology, Immunology and Parasitology, Medical Sciences College (FCM), Rio de Janeiro State University (UERJ), Rio de Janeiro, Brazil. Electronic address: machado@uerj.br.

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Classifications MeSH