Endocrine therapy for metastatic solid pseudopapillary neoplasm of the pancreas: A case report.
case report
endocrine therapy
pancreas
solid pseudopapillary neoplasm (SPN)
tamoxifen
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2022
2022
Historique:
received:
15
06
2022
accepted:
23
08
2022
entrez:
30
9
2022
pubmed:
1
10
2022
medline:
1
10
2022
Statut:
epublish
Résumé
Solid pseudopapillary neoplasm (SPN) of the pancreas is an extremely rare tumor, associated with favorable prognosis and long-term survival in patients with advanced disease. However, limited data exist on systemic therapy for such patients. Herein, we present a case of a young woman with a history of SPN, who progressed after multiple surgical resections and chemotherapy regimens. The immunohistochemistry (IHC) showed overexpression of estrogen receptors (ER) and progesterone receptors (PR) in tumor tissue. The patient started to receive tamoxifen and showed a durable response to endocrine therapy.
Identifiants
pubmed: 36176411
doi: 10.3389/fonc.2022.970142
pmc: PMC9514425
doi:
Types de publication
Case Reports
Langues
eng
Pagination
970142Informations de copyright
Copyright © 2022 Kornietskaya, Evdokimova, Kachmazov, Fedenko, Bolotina, Sidorov, Volchenko, Goeva, Govaleshko and Kaprin.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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