Urethral metastasis from esophageal cancer: symptoms of dysuria and cystoscopic diagnosis.


Journal

Oxford medical case reports
ISSN: 2053-8855
Titre abrégé: Oxf Med Case Reports
Pays: England
ID NLM: 101642070

Informations de publication

Date de publication:
Sep 2022
Historique:
received: 26 04 2022
revised: 06 08 2022
accepted: 11 08 2022
entrez: 30 9 2022
pubmed: 1 10 2022
medline: 1 10 2022
Statut: epublish

Résumé

Urethral malignant tumors are rare and can lead to stenosis, causing dysuria. We report a case of urethral metastasis secondary to esophageal cancer. At the time of diagnosis, a patient with esophageal squamous cell carcinoma presented with voiding difficulties, feeble stream, terminal dribbling and incomplete voiding. The urethral tumor was diagnosed using cystoscopy, and biopsy was thereafter performed. Histopathology of the urethral tumor microscopically resembled to that of esophageal cancer. On immunohistochemistry, the urothelium markers uroplakin 2 and GATA3 were negative in the carcinomatous component; however, GATA3 was detected on the lesion's surface. This case demonstrated that esophageal cancer metastasized to the urethra. Medical oncologists should consider this diagnosis in patients with cancer presenting with dysuria.

Identifiants

pubmed: 36176944
doi: 10.1093/omcr/omac099
pii: omac099
pmc: PMC9514107
doi:

Types de publication

Case Reports

Langues

eng

Pagination

omac099

Informations de copyright

© The Author(s) 2022. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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Auteurs

Saya Kitashiro (S)

Department of Medical Oncology, Yodogawa Christian Hospital, Osaka, Japan.

Ikumi Kuno (I)

Department of Medical Oncology, Yodogawa Christian Hospital, Osaka, Japan.

Tenyu Sugano (T)

Department of Diagnostic Pathology, Yodogawa Christian Hospital, Osaka, Japan.

Yukimasa Yamano (Y)

Department of Urology, Yodogawa Christian Hospital, Osaka, Japan.

Yasushi Shigeoka (Y)

Department of Medical Oncology, Yodogawa Christian Hospital, Osaka, Japan.

Mayumi Inaba (M)

Department of Diagnostic Pathology, Yodogawa Christian Hospital, Osaka, Japan.

Classifications MeSH