A Systematic Review of the Gastrointestinal Microbiome: A Game Changer in Colorectal Cancer.
colorectal cancer
colorectal neoplasm
gastrointestinal
gastrointestinal microbiome
gut microbiome
gut microflora
microbiome
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Aug 2022
Aug 2022
Historique:
received:
16
06
2022
accepted:
27
08
2022
entrez:
3
10
2022
pubmed:
4
10
2022
medline:
4
10
2022
Statut:
epublish
Résumé
Colorectal cancer (CRC) is a malignant condition of the colon and rectum. Generally, malignancies constitute a significant health threat to humans, and the result can be devastating. CRC is no exception. The gastrointestinal (GI) microbiome has long been suspected of impacting CRC. This review seeks to explore whether there is a connection between the two or not. For screening purposes, relevant articles were culled from various databases using key terms and phrases. Following a thorough search, the inclusion and exclusion criteria were applied, and a quality assessment was conducted. The articles retained were comprehensively studied, and revealed imbalances of the GI microbiome do indeed exhibit an association with CRC.
Identifiants
pubmed: 36185901
doi: 10.7759/cureus.28545
pmc: PMC9514148
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
e28545Informations de copyright
Copyright © 2022, Eastmond et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Oncotarget. 2013 Nov;4(11):1860-1
pubmed: 24163267
Nat Med. 2019 Apr;25(4):679-689
pubmed: 30936547
Theranostics. 2019 May 31;9(14):4101-4114
pubmed: 31281534
BMJ. 2021 Mar 29;372:n71
pubmed: 33782057
Int J Mol Sci. 2017 Jun 20;18(6):
pubmed: 28632155
BMC Microbiol. 2018 Aug 29;18(1):92
pubmed: 30157754
Gut. 2019 Apr;68(4):654-662
pubmed: 30472682
Gut. 2017 Jan;66(1):70-78
pubmed: 26408641
Microbiome. 2016 Dec 30;4(1):69
pubmed: 28038683
Int J Mol Sci. 2019 Oct 24;20(21):
pubmed: 31653078
Theranostics. 2020 Sep 18;10(25):11595-11606
pubmed: 33052235
Sci Rep. 2021 Feb 3;11(1):2925
pubmed: 33536501
CA Cancer J Clin. 2017 May 6;67(3):177-193
pubmed: 28248415
Molecules. 2017 Jan 10;22(1):
pubmed: 28075415
World J Gastroenterol. 2016 Jan 14;22(2):501-18
pubmed: 26811603