Molecular insights into Mmpl3 leads to the development of novel indole-2-carboxamides as antitubercular agents.
Mmpl3
antitubercular
indole-2-carboxamides
molecular dynamics
structural insights
Journal
Molecular systems design & engineering
ISSN: 2058-9689
Titre abrégé: Mol Syst Des Eng
Pays: England
ID NLM: 101683399
Informations de publication
Date de publication:
01 Jun 2022
01 Jun 2022
Historique:
entrez:
3
10
2022
pubmed:
4
10
2022
medline:
4
10
2022
Statut:
ppublish
Résumé
Tuberculosis (TB) is an air-borne infectious disease and is the leading cause of death among all infectious diseases globally. The current treatment regimen for TB is overtly long and patient non-compliance often leads to drug resistant TB resulting in a need to develop new drugs that will act via novel mechanisms. In this research work, we selected
Identifiants
pubmed: 36186547
doi: 10.1039/d1me00122a
pmc: PMC9518744
mid: NIHMS1790531
doi:
Types de publication
Journal Article
Langues
eng
Pagination
592-606Subventions
Organisme : Intramural NIH HHS
ID : Z01 AI000693
Pays : United States
Déclaration de conflit d'intérêts
Conflict of interest statement There are no conflicts to declare.
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