Investigating the anticancer efficacy of biogenic synthesized MgONPs: An
MgONPs
anticancer
biogenic
cytotoxicity
electron microscopy
Journal
Frontiers in chemistry
ISSN: 2296-2646
Titre abrégé: Front Chem
Pays: Switzerland
ID NLM: 101627988
Informations de publication
Date de publication:
2022
2022
Historique:
received:
15
06
2022
accepted:
25
08
2022
entrez:
3
10
2022
pubmed:
4
10
2022
medline:
4
10
2022
Statut:
epublish
Résumé
The biogenic approach of synthesizing metal nanoparticles is an exciting and interesting research area with a wide range of applications. The present study reports a simple, convenient, low-cost method for synthesizing magnesium oxide nanoparticles (MgONPs) from pumpkin seed extracts and their anticancer efficacy against ovarian teratocarcinoma cell line (PA-1). The characteristic features of biogenic MgONPs were assessed by UV-visible spectrophotometry (UV-vis), X-ray powder diffraction (XRD), scanning electron microscopy (SEM), and transmission electron microscopy (TEM). The formation of spherical NPs with an average size of 100 nm was observed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). Moreover, MgONPs exhibit considerable cytotoxicity with an IC
Identifiants
pubmed: 36186592
doi: 10.3389/fchem.2022.970193
pii: 970193
pmc: PMC9520594
doi:
Types de publication
Journal Article
Langues
eng
Pagination
970193Informations de copyright
Copyright © 2022 Tabrez, Khan, Hoque, Suhail, Khan and Zughaibi.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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