Common Bias and Challenges in Physical and Rehabilitation Medicine Research: How to Tackle Them.
clinical trial
evidence-based medicine (EBM)
study design
traumatology
treatment
Journal
Frontiers in rehabilitation sciences
ISSN: 2673-6861
Titre abrégé: Front Rehabil Sci
Pays: Switzerland
ID NLM: 9918227358906676
Informations de publication
Date de publication:
2022
2022
Historique:
received:
10
02
2022
accepted:
19
05
2022
entrez:
3
10
2022
pubmed:
4
10
2022
medline:
4
10
2022
Statut:
epublish
Résumé
The importance of evidence-based medicine is crucial, especially in physical and rehabilitation medicine (PRM), where there is a need to conduct rigorous experimental protocols, as in any medical field. Currently, in clinical practice, therapeutic approaches are often based on empirical data rather than evidence-based medicine. However, the field of PRM faces several challenges that may complicate scientific research. In addition, there is often a lack of appropriate research training in educational programs. In this context, we aim to review the methodological challenges in PRM and provide clear examples for each of them as well as potential solutions when possible. This article will cover the following themes: (1) Choosing the right study design and conducting randomized and benchmarking controlled trials; (2). Selecting the appropriate controlled, placebo or sham condition and the issue of blinding in non-pharmacological trials; (3) The impact of populations' heterogeneity and multi-comorbidities; (4). The challenge of recruitment and adherence; (5). The importance of homogeneity and proper quantification of rehabilitative strategies; and (6). Ethical issues. We are convinced that teaching the basics of scientific research in PRM could help physicians and therapists to choose a treatment based on (novel) scientific evidence. It may also promote scientific research in PRM to develop novel and personalized rehabilitation strategies using rigorous methodologies and randomized or benchmarking controlled trials in order to improve patients' management.
Identifiants
pubmed: 36189055
doi: 10.3389/fresc.2022.873241
pmc: PMC9397780
doi:
Types de publication
Journal Article
Langues
eng
Pagination
873241Informations de copyright
Copyright © 2022 Thibaut, Beaudart, Martens, Bornheim and Kaux.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
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