Annexin V
Annexin V(-) and tissue factor(+) microparticles
Joint arthroplasty
Vein thromboembolism
Journal
Clinica chimica acta; international journal of clinical chemistry
ISSN: 1873-3492
Titre abrégé: Clin Chim Acta
Pays: Netherlands
ID NLM: 1302422
Informations de publication
Date de publication:
01 Nov 2022
01 Nov 2022
Historique:
received:
21
02
2021
revised:
29
08
2022
accepted:
08
09
2022
pubmed:
4
10
2022
medline:
20
10
2022
entrez:
3
10
2022
Statut:
ppublish
Résumé
Venous thromboembolism (VTE) is a common and severe complication of joint arthroplasty. Microparticles (MPs) containing phosphatidylserine (PS) and tissue factor (TF) can trigger coagulation in VTE. This study aims to measure and compare MP levels in joint arthroplasty patients with and without VTE. This prospective cohort study enrolled 181 patients who underwent joint arthroplasty. Ultrasound examination was used to diagnose VTE on preoperative day 0 and postoperative day 6. MPs were analysed using transmission electron microscopy (TEM), nanoparticle tracking analysis (NTA), and flow cytometry. The levels of platelet-derived microparticles (PMPs), endothelial cell-derived microparticles (EMPs), granulocyte-derived microparticles (GMPs), red cell-derived microparticles (RMPs), monocyte-derived microparticles (MMPs), Annexin V The levels of AV AV
Identifiants
pubmed: 36191610
pii: S0009-8981(22)01300-6
doi: 10.1016/j.cca.2022.09.011
pii:
doi:
Substances chimiques
Annexin A5
0
Biomarkers
0
Phosphatidylserines
0
Thromboplastin
9035-58-9
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
169-179Informations de copyright
Copyright © 2022. Published by Elsevier B.V.
Déclaration de conflit d'intérêts
Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.