New
Plasmodium
drug combinations
drug-drug interactions
in vitro-in silico preclinical strategy
pharmacometric models
Journal
Antimicrobial agents and chemotherapy
ISSN: 1098-6596
Titre abrégé: Antimicrob Agents Chemother
Pays: United States
ID NLM: 0315061
Informations de publication
Date de publication:
15 11 2022
15 11 2022
Historique:
pubmed:
6
10
2022
medline:
18
11
2022
entrez:
5
10
2022
Statut:
ppublish
Résumé
The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine optimal combination and dosing regimens. To support the selection of new combinations, we developed a novel
Identifiants
pubmed: 36197116
doi: 10.1128/aac.00556-22
pmc: PMC9664866
doi:
Substances chimiques
Antimalarials
0
ferroquine
8D81JS19ET
artefenomel
RIK029813G
Drug Combinations
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e0055622Références
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