Management of IgE-mediated food allergy in the 21st century.
Journal
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology
ISSN: 1365-2222
Titre abrégé: Clin Exp Allergy
Pays: England
ID NLM: 8906443
Informations de publication
Date de publication:
01 2023
01 2023
Historique:
revised:
15
09
2022
received:
01
07
2022
accepted:
26
09
2022
pubmed:
7
10
2022
medline:
24
1
2023
entrez:
6
10
2022
Statut:
ppublish
Résumé
The 21st century has seen the propulsion of research in the field of food allergy, which has driven real changes in the clinical approach. Allergen immunotherapy has been recommended for the active management of food allergy. Data have shown promising additional methods of treatment, including biologics. Efforts have been devoted to the risk stratification of food allergy and the standardization of the assessment of food-allergic severity. Alternative routes of administration of epinephrine are under investigation to minimize any mechanical issue and the fear of injections. Evidence-based guidelines have been published by the main international societies in the field of anaphylaxis and food allergy management and new updates are in preparation. In the coming years, treatment options that are currently in pre-clinical or early clinical evaluation will hopefully lead to safe and effective disease-modifying therapies for food allergy in clinical practice. The identification of reliable biomarkers and the standardization of definitions and measurement approaches, alongside a shared decision-making with patients and families, will be key for the development of personalized care and to help minimize the substantial burden of food allergy.
Identifiants
pubmed: 36200952
doi: 10.1111/cea.14241
pmc: PMC10092460
doi:
Substances chimiques
Immunoglobulin E
37341-29-0
Allergens
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
25-38Informations de copyright
© 2022 The Authors. Clinical & Experimental Allergy published by John Wiley & Sons Ltd.
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