Effect of maternal adverse childhood experiences (ACE) and cannabis use on pregnancy outcomes.
Cannabis
Pregnancy
Trauma
Journal
Archives of women's mental health
ISSN: 1435-1102
Titre abrégé: Arch Womens Ment Health
Pays: Austria
ID NLM: 9815663
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
received:
11
03
2022
accepted:
14
09
2022
pubmed:
7
10
2022
medline:
15
12
2022
entrez:
6
10
2022
Statut:
ppublish
Résumé
This study aimed to characterize the relationship between cannabis use, ACE score, and pregnancy outcomes. Pregnant patients in Baltimore, MD, completed the 17-point ACE checklist. Charts of the birth parent and neonate were reviewed for urine toxicology testing at initiation of care and delivery, prenatal care metrics, and birth statistics. Multivariable logistic regression analysis was performed to assess the relationship between ACE score, cannabis use, and pregnancy outcomes. Of 256 birth parents, 87 (34.0%) tested positive for cannabis at initial visit and 39 (15.2%) tested positive for cannabis at delivery. Testing positive for cannabis at initial visit or delivery was associated with higher ACE score (15.1 vs 13.7, p = 0.04; 16.2 vs 13.8, p = 0.01). Of those who tested positive for cannabis at initial visit, 39/87 (45.0%) tested positive at delivery. Continued cannabis use at delivery was associated with lower maternal weight gain (7.9 kg vs 13.3 kg, p = 0.003), fewer prenatal visits (7 vs 8, p = 0.010), and numerically higher mean ACE score. Cannabis use at delivery was associated with 10% lower birthweight (2665 g vs 3014 g p < 0.05) but not with pre-term birth. Total ACE score was not significantly associated with any birth outcome. Worse pregnancy outcomes were associated with cannabis use throughout pregnancy but not with cannabis use at prenatal care initiation. The interplay of ACE and continued cannabis use during pregnancy warrants further research on the physiologic effects of cannabis and interventions to decrease substance use during pregnancy.
Identifiants
pubmed: 36203114
doi: 10.1007/s00737-022-01269-x
pii: 10.1007/s00737-022-01269-x
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1097-1104Informations de copyright
© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.
Références
Appleton AA, Kiley K, Holdsworth EA, Schell LM (2019) Social support during pregnancy modifies the association between maternal adverse childhood experiences and infant birth size. Matern Child Health J 23(3):408–415
doi: 10.1007/s10995-018-02706-z
Bhengu B., T. A., Mashaphu S., Paruk S. (2019, epub ahead of print. ). “The role of adverse childhood experiences on perinatal substance use behavior in KwaZulu-Natal Province, South Africa.” Aids and Behavior.
Brown QL, Sarvet AL, Shmulewitz D, Martins SS, Wall MM, Hasin DS (2017) Trends in marijuana use among pregnant and nonpregnant reproductive-aged women, 2002–2014. JAMA 317(2):207–209
doi: 10.1001/jama.2016.17383
Christiaens I, Hegadoren K, Olson DM (2015) Adverse childhood experiences are associated with spontaneous preterm birth: a case-control study. BMC Med 13:124
doi: 10.1186/s12916-015-0353-0
Corsi DJ, Walsh L, Weiss D, Hsu H, El-Chaar D, Hawken S, Fell DB, Walker M (2019) Association Between self-reported prenatal cannabis use and maternal, perinatal, and neonatal outcomes. JAMA 322(2):145–152
doi: 10.1001/jama.2019.8734
Crume TL, Juhl AL, Brooks-Russell A, Hall KE, Wymore E, Borgelt LM (2018) Cannabis use during the perinatal period in a state with legalized recreational and medical marijuana: the association between maternal characteristics, breastfeeding patterns, and neonatal outcomes. J Pediatr 197:90–96
doi: 10.1016/j.jpeds.2018.02.005
Dube SR, Felitti VJ, Dong M, Chapman DP, Giles WH, Anda RF (2003) Childhood abuse, neglect, and household dysfunction and the risk of illicit drug use: the adverse childhood experiences study. Pediatrics 111(3):564–572
doi: 10.1542/peds.111.3.564
El Marroun H, Tiemeier H, Steegers EA, Jaddoe VW, Hofman A, Verhulst FC, van den Brink W, Huizink AC (2009) Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R Study. J Am Acad Child Adolesc Psychiatry 48(12):1173–1181
doi: 10.1097/CHI.0b013e3181bfa8ee
ElSohly MA, Mehmedic Z, Foster S, Gon C, Chandra S, Church JC (2016) Changes in cannabis potency over the last 2 decades (1995–2014): Analysis of current data in the United States. Biol Psychiatry 79(7):613–619
doi: 10.1016/j.biopsych.2016.01.004
Felitti VJ, Anda RF, Nordenberg D, Williamson DF, Spitz AM, Edwards V, Koss MP, Marks JS (1998) Relationship of childhood abuse and household dysfunction to many of the leading causes of death in adults. The adverse childhood experiences (ACE) study. Am J Prev Med 14(4):245–258
doi: 10.1016/S0749-3797(98)00017-8
Frankenberger DJ, Clements-Nolle K, Yang W (2015) The association between adverse childhood experiences and alcohol use during pregnancy in a representative sample of adult women. Womens Health Issues 25(6):688–695
doi: 10.1016/j.whi.2015.06.007
Gillespie SL, Christian LM, Alston AD, Salsberry PJ (2017) Childhood stress and birth timing among African American women: cortisol as biological mediator. Psychoneuroendocrinology 84:32–41
doi: 10.1016/j.psyneuen.2017.06.009
Hughes K, Bellis MA, Hardcastle KA, Sethi D, Butchart A, Mikton C, Jones L, Dunne MP (2017) The effect of multiple adverse childhood experiences on health: a systematic review and meta-analysis. Lancet Public Health 2(8):e356–e366
doi: 10.1016/S2468-2667(17)30118-4
Ko, J. Y., S. L. Farr, V. T. Tong, A. A. Creanga and W. M. Callaghan (2015). “Prevalence and patterns of marijuana use among pregnant and nonpregnant women of reproductive age.” Am J Obstet Gynecol 213(2): 201 e201–201 e210.
Kornfield SL, Moseley M, Appleby D, McMickens CL, Sammel MD, Epperson CN (2017) Posttraumatic symptom reporting and reported cigarette smoking during pregnancy. J Womens Health (larchmt) 26(6):662–669
doi: 10.1089/jwh.2016.5928
LeTendre ML, Reed MB (2017) The Effect of Adverse Childhood experience on clinical diagnosis of a substance use disorder: results of a nationally representative study. Subst Use Misuse 52(6):689–697
doi: 10.1080/10826084.2016.1253746
Mark K, Gryczynski J, Axenfeld E, Schwartz RP, Terplan M (2017) Pregnant women’s current and intended cannabis use in relation to their views toward legalization and knowledge of potential harm. J Addict Med 11(3):211–216
doi: 10.1097/ADM.0000000000000299
Mark K, Khan A, Terplan M (2020a) Cannabis use as determined by biologic testing in maternal and newborn urines during a period of drug liberalization. Subst Use Misuse 55(8):1343–1346
doi: 10.1080/10826084.2020.1741634
Mark K, Pierce E, Joseph D, Crimmins S (2020b) Interaction with the justice system and other factors associated with pregnant women’s self-report and continuation of use of marijuana. Drug Alcohol Depend 206:107723
doi: 10.1016/j.drugalcdep.2019.107723
Mark K, Otieno L, Moore E, Zehra A, Mitchell M (2021) Association between continued cannabis use during pregnancy and symptoms of anxiety and depression. Int Rev Psychiatry 33(6):528–533
doi: 10.1080/09540261.2021.1898348
Massey SH, Neiderhiser JM, Shaw DS, Leve LD, Ganiban JM, Reiss D (2012) Maternal self concept as a provider and cessation of substance use during pregnancy. Addict Behav 37(8):956–961
doi: 10.1016/j.addbeh.2012.04.002
Mersky JP, Lee CP (2019) Adverse childhood experiences and poor birth outcomes in a diverse, low-income sample. BMC Pregnancy Childbirth 19(1):387
doi: 10.1186/s12884-019-2560-8
Mersky JP, Janczewski CE, Topitzes J (2017) Rethinking the measurement of adversity. Child Maltreat 22(1):58–68
doi: 10.1177/1077559516679513
Metz TD, Borgelt LM (2018) Marijuana use in pregnancy and while breastfeeding. Obstet Gynecol 132(5):1198–1210
doi: 10.1097/AOG.0000000000002878
Miller ES, Fleming O, Ekpe EE, Grobman WA, Heard-Garris N (2021) Association between adverse childhood experiences and adverse pregnancy outcomes. Obstet Gynecol 138(5):770–776
doi: 10.1097/AOG.0000000000004570
Osofsky JD, Osofsky HJ, Frazer AL, Fields-Olivieri MA, Many M, Selby M, Holman S, Conrad E (2021) The importance of adverse childhood experiences during the perinatal period. Am Psychol 76(2):350–363
doi: 10.1037/amp0000770
Rodriguez CE, Sheeder J, Allshouse AA, Scott S, Wymore E, Hopfer C, Hermesch A, Metz TD (2019) Marijuana use in young mothers and adverse pregnancy outcomes: a retrospective cohort study. BJOG 126(12):1491–1497
doi: 10.1111/1471-0528.15885
Smith MV, Gotman N, Yonkers KA (2016) Early childhood adversity and pregnancy outcomes. Matern Child Health J 20(4):790–798
doi: 10.1007/s10995-015-1909-5
Sulaiman S, Premji SS, Tavangar F, Yim IS, Lebold M, MiGht (2021) Total adverse childhood experiences and preterm birth: a systematic review. Matern Child Health J 25(10):1581–1594
doi: 10.1007/s10995-021-03176-6
Testa A, Jackson DB, Boccio C, Ganson KT, Nagata JM (2022) Adverse childhood experiences and marijuana use during pregnancy: findings from the North Dakota and South Dakota PRAMS, 2017–2019. Drug Alcohol Depend 230:109197
doi: 10.1016/j.drugalcdep.2021.109197
Thompson R, DeJong K, Lo J (2019) Marijuana use in pregnancy: a review. Obstet Gynecol Surv 74(7):415–428
doi: 10.1097/OGX.0000000000000685
Volkow ND, Han B, Compton WM, Blanco C (2017) Marijuana use during stages of pregnancy in the United States. Ann Intern Med 166(10):763–764
doi: 10.7326/L17-0067
Volkow ND, Han B, Compton WM, McCance-Katz EF (2019) Self-reported medical and nonmedical cannabis use among pregnant women in the United States. JAMA 322(2):167–169
doi: 10.1001/jama.2019.7982
Young-Wolff KC, Sarovar V, Tucker LY, Avalos LA, Alexeeff S, Conway A, Armstrong MA, Weisner C, Campbell CI, Goler N (2019) Trends in marijuana use among pregnant women with and without nausea and vomiting in pregnancy, 2009–2016. Drug Alcohol Depend 196:66–70
doi: 10.1016/j.drugalcdep.2018.12.009