Detection of rare autoreactive T cell subsets in patients with pemphigus vulgaris.


Journal

Frontiers in immunology
ISSN: 1664-3224
Titre abrégé: Front Immunol
Pays: Switzerland
ID NLM: 101560960

Informations de publication

Date de publication:
2022
Historique:
received: 27 06 2022
accepted: 29 08 2022
entrez: 7 10 2022
pubmed: 8 10 2022
medline: 12 10 2022
Statut: epublish

Résumé

Analysis of T lymphocyte proliferation and activation after antigenic or mitogenic stimulation is a vital parameter used in the diagnosis of various immuno-deficiencies and during the monitoring of treatment responses. Most applied techniques are based on the incorporation of tritiated thymidine (

Identifiants

pubmed: 36203615
doi: 10.3389/fimmu.2022.979277
pmc: PMC9531257
doi:

Substances chimiques

Autoantigens 0
Cytokines 0
Epitopes 0
Immunoglobulin G 0
Interleukin-17 0
CD40 Ligand 147205-72-9
Thymidine VC2W18DGKR

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

979277

Informations de copyright

Copyright © 2022 Polakova, Kauter, Ismagambetova, Didona, Solimani, Ghoreschi, Hertl, Möbs and Hudemann.

Déclaration de conflit d'intérêts

MH is a recipient of an unrestricted grant from TOPAS Therapeutics relating to a collaboration aimed at inducing therapeutic T cell tolerance in pemphigus. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Alexandra Polakova (A)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Leonie Kauter (L)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Adina Ismagambetova (A)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Dario Didona (D)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Farzan Solimani (F)

Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
Berlin Institute of Health at Charité - Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Berlin, Germany.

Kamran Ghoreschi (K)

Department of Dermatology, Venereology and Allergology, Charité-Universitätsmedizin Berlin, Berlin, Germany.

Michael Hertl (M)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Christian Möbs (C)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

Christoph Hudemann (C)

Department of Dermatology and Allergology, Philipps-Universität Marburg, Marburg, Germany.

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