Population-based cohort study to assess the gingival lesions in 1319 patients with lichen planus.


Journal

Oral diseases
ISSN: 1601-0825
Titre abrégé: Oral Dis
Pays: Denmark
ID NLM: 9508565

Informations de publication

Date de publication:
Nov 2023
Historique:
revised: 18 08 2022
received: 25 04 2022
accepted: 02 10 2022
medline: 7 12 2023
pubmed: 9 10 2022
entrez: 8 10 2022
Statut: ppublish

Résumé

Oral lichen planus (OLP) is a chronic immune disease. In this paper, we evaluated the overall characters, clinical presentation, and outcome of gingival lesions in OLP Italian patients. A retrospective cohort study was accomplished: a total of 1319 charts were investigated, of whom 922 were female (69.9%): 617 patients (46.8%) manifested white lesions and 702 red ones (53.2%). While most patients had several oral sites of involvement, the gingiva was the unique location in 103 cases. Symptoms were reported in 480 patients (36.4%): 286 patients with erosive OLP, 103 with atrophic form, and 91 with a white form. Long-lasting surveillance showed that only 40 patients (3.03%) had a total clinical signs remission. Regarding OLP medical treatment provided, patients attending less frequently a dental office underwent more often a specific therapy. To the best of our knowledge, this is the biggest collections of patients with gingival OLP ever described; exclusive gingival lesions are, however, rare and unlikely to undergo a malignant transformation. Moreover, gum lesions seemed to anticipate the appearance of oral lesions and a higher rate of OLP therapy was observed in patients with less frequent dental check-ups and oral hygiene instructions.

Identifiants

pubmed: 36208128
doi: 10.1111/odi.14398
doi:

Types de publication

Journal Article

Langues

eng

Pagination

3393-3399

Informations de copyright

© 2022 Wiley Periodicals LLC.

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Auteurs

Paolo G Arduino (PG)

Department of Surgical Sciences, Oral Medicine Section, CIR-Dental School, University of Turin, Turin, Italy.

Alessio Gambino (A)

Department of Surgical Sciences, Oral Medicine Section, CIR-Dental School, University of Turin, Turin, Italy.

Alessandra Macciotta (A)

Department of Clinical and Biological Sciences, University of Turin, Turin, Italy.

Giorgia El Haddad (G)

Department of Surgical Sciences, Oral Medicine Section, CIR-Dental School, University of Turin, Turin, Italy.

Davide Conrotto (D)

Department of Surgical Sciences, Oral Medicine Section, CIR-Dental School, University of Turin, Turin, Italy.

Mario Carbone (M)

Department of Surgical Sciences, Oral Medicine Section, CIR-Dental School, University of Turin, Turin, Italy.

Marco Carrozzo (M)

Department of Oral Medicine, School of Dental Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne, UK.

Roberto Broccoletti (R)

Department of Surgical Sciences, Oral Medicine Section, CIR-Dental School, University of Turin, Turin, Italy.

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