Prolonged lapses between pediatric and adult care are associated with rise in HbA1c and inpatient days among patients with type 1 diabetes.


Journal

Diabetes research and clinical practice
ISSN: 1872-8227
Titre abrégé: Diabetes Res Clin Pract
Pays: Ireland
ID NLM: 8508335

Informations de publication

Date de publication:
Oct 2022
Historique:
received: 05 05 2022
revised: 16 09 2022
accepted: 30 09 2022
pubmed: 9 10 2022
medline: 2 11 2022
entrez: 8 10 2022
Statut: ppublish

Résumé

To quantify the association between the duration of the pediatric-to-adult care transfer with glycemic control among patients with type 1 diabetes (T1D). This retrospective cohort study included patients with T1D who completed transfer between pediatric and adult diabetes clinics at a single academic medical center between 2004 and 2020. The primary exposure was time from the last pediatric to first adult diabetes care encounter. The primary outcome was the average HbA1c in the first year after entry into adult care. A total of 449 patients (mean age at transfer 19.8yrs, 51.7 % male) were included for analysis. Transfer required a median of nearly 5 months (196 days; IQR:93-251) and in adjusted and unadjusted models was strongly associated with increased HbA1c within 1 year of transfer (0.19 %, 2 mmol/mol; 95 %CI:0.04 %-0.33 %) for each 6 months of latency. In secondary analyses, transfer latency also exhibited a significant association with days spent hospitalized (IRR 1.23 per 6 months; 95 %CI:1.08-1.33). Our findings isolate and quantify the impact of prolonged lapses in care associated with the pediatric-to-adult care transfer. These findings underscore the need for providers and healthcare systems to improve this care transition in order to improve outcomes for this vulnerable patient population.

Identifiants

pubmed: 36208847
pii: S0168-8227(22)00927-5
doi: 10.1016/j.diabres.2022.110113
pmc: PMC9867942
mid: NIHMS1862510
pii:
doi:

Substances chimiques

Glycated Hemoglobin A 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

110113

Subventions

Organisme : NIDDK NIH HHS
ID : P30 DK020593
Pays : United States
Organisme : NIDDK NIH HHS
ID : R01 DK115545
Pays : United States
Organisme : NIDDK NIH HHS
ID : T32 DK007061
Pays : United States
Organisme : NCATS NIH HHS
ID : UL1 TR002243
Pays : United States

Informations de copyright

Copyright © 2022 Elsevier B.V. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Daniel R Tilden (DR)

Division of Endocrinology, Diabetes, and Clinical Pharmacology, Department of Medicine, University of Kansas Medical Center, Kansas City, KS, United States. Electronic address: dtilden@kumc.edu.

Benjamin French (B)

Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, United States.

Ashley H Shoemaker (AH)

Ian M. Burr Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.

Sarah Corathers (S)

Division of Endocrinology, Cincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, United States.

Sarah S Jaser (SS)

Ian M. Burr Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States; Division of Pediatric Psychology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, United States.

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