Nonneoplastic and noninfective cysts of the central nervous system: A histopathological study.
central nervous system
epithelial cysts
non-infectious
non-neoplastic
outcome
Journal
Neuropathology : official journal of the Japanese Society of Neuropathology
ISSN: 1440-1789
Titre abrégé: Neuropathology
Pays: Australia
ID NLM: 9606526
Informations de publication
Date de publication:
Jun 2023
Jun 2023
Historique:
revised:
23
08
2022
received:
19
05
2022
accepted:
24
08
2022
medline:
5
6
2023
pubmed:
11
10
2022
entrez:
10
10
2022
Statut:
ppublish
Résumé
Nonneoplastic epithelial cysts involving the central nervous system are diverse and are predominantly developmental in origin. This study represents a surgical series describing the histopathological features of 507 such epithelial cysts with clinical and imaging correlation. Age at surgery ranged from 7 months to 72 years (mean: 33 years) affecting 246 male and 261 female patients. Colloid cyst was the most frequently resected cyst, followed by epidermoid cyst, arachnoid cyst, Rathke cleft cyst, dermoid cyst, neurenteric cyst, Tarlov cyst, and choroid plexus cyst. Diagnosis was based on the location of the cysts and the nature of the lining epithelium. Rathke cleft cyst showed the highest propensity for squamous metaplasia, significant inflammation, and xanthogranulomatous reaction. Ulceration of lining epithelium and calcification were most frequent in dermoid cyst. Radiopathological concordance was maximal for colloid cyst, followed by epidermoid and arachnoid cysts. Epidermoid and dermoid cysts exhibited the highest propensity for local tumor progression, followed by Rathke cleft cyst.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
221-232Informations de copyright
© 2022 Japanese Society of Neuropathology.
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