Recurrence of chronic subdural hematoma due to low-grade infection.

MMA occlusion chronic subdural hematoma dexamethasone infected subdural hematoma recurrence recurrence

Journal

Frontiers in neurology
ISSN: 1664-2295
Titre abrégé: Front Neurol
Pays: Switzerland
ID NLM: 101546899

Informations de publication

Date de publication:
2022
Historique:
received: 05 08 2022
accepted: 01 09 2022
entrez: 10 10 2022
pubmed: 11 10 2022
medline: 11 10 2022
Statut: epublish

Résumé

Despite the high incidence and multitudes of operative techniques, the risk factors for chronic subdural hematoma (CSDH) recurrence are still under debate and a universal consensus on the pathophysiology is lacking. We hypothesized that clinically inapparent, a low-grade infection could be responsible for CSDH recurrence. This investigation is a single-center prospective observational study including patients with recurrent CSDH. In total, 44 patients with CSDH recurrence received an intraoperative swab-based microbiological test. The intraoperative swab revealed an inapparent low-grade hematoma infection in 29% of the recurrent CSDH cases. The majority (69%) of the identified germs belonged to the

Identifiants

pubmed: 36212639
doi: 10.3389/fneur.2022.1012255
pmc: PMC9539083
doi:

Types de publication

Journal Article

Langues

eng

Pagination

1012255

Informations de copyright

Copyright © 2022 Dubinski, Won, Trnovec, Gounko, Baumgarten, Warnke, Cantré, Behmanesh, Bernstock, Freiman, Gessler and Sola.

Déclaration de conflit d'intérêts

Author DD received financial support from Novartis, Fresenius, Inovitro, and Novocure. None of these entities were involved in the study design, collection, analysis, interpretation of data, the writing of this article or the decision to submit it for publication. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Daniel Dubinski (D)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Sae-Yeon Won (SY)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Svorad Trnovec (S)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Kseniya Gounko (K)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Peter Baumgarten (P)

Department of Neurosurgery, University Hospital, Schiller University Jena, Jena, Germany.

Philipp Warnke (P)

Institute for Medical Microbiology, Virology and Hygiene, Rostock University Medical Center, Rostock, Germany.

Daniel Cantré (D)

Institute of Diagnostic and Interventional Radiology, Pediatric Radiology and Neuroradiology, Rostock University Medical Center, Rostock, Germany.

Bedjan Behmanesh (B)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Joshua D Bernstock (JD)

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

Thomas M Freiman (TM)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Florian Gessler (F)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Steffen Sola (S)

Department of Neurosurgery, Rostock University Medical Center, Rostock, Germany.

Classifications MeSH