Cigarette smoking and adverse health outcomes in patients treated with maintenance dialysis.
dialysis
mortality
smoking
Journal
Nephrology (Carlton, Vic.)
ISSN: 1440-1797
Titre abrégé: Nephrology (Carlton)
Pays: Australia
ID NLM: 9615568
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
revised:
01
10
2022
received:
06
08
2022
accepted:
08
10
2022
pubmed:
13
10
2022
medline:
20
12
2022
entrez:
12
10
2022
Statut:
ppublish
Résumé
The association of smoking with new-onset cardiovascular disease, chronic lung disease, malignancy and mortality in dialysis is well-known. The smoking prevalence and its association with clinical outcome was assessed. Multicentre cohort study using 'ANZDATA' Registry, 57 838 adults who commenced dialysis (>3 months) between 1990 and 2016 were included. Patients' demographics, initial dialysis modality, presence of comorbidities and smoking history are predictors. The primary outcome was all-cause mortality. Secondary outcomes were smoking prevalence, cause-specific mortality, non-skin cancers, cardiovascular and chronic lung diseases. Of the 57 838 patients, 56 512 (mean age of 58.9 ± 15.1 years, 40.1% female, 43% diabetic), had data on smoking history with 13.6% current, 40.7% former and 45.6% never smokers. Former and current smokers had 10% (HR 1.10; 95% CI: 1.08, 1.13) and 22%(HR 1.22; 95% CI: 1.18, 1.26) higher risk of all-cause mortality. They were 13% (HR 1.13; 95% CI: 1.09, 1.18) and 23% (HR 1.23; 95% CI: 1.17, 1.29) for CVD mortality. Smoking was associated with higher mortality from respiratory failure (HR 1.59; 95% CI: 1.13, 2.23, p = .073 and HR 1.33; 95% CI: 1.01, 1.74, p = .042) for current and former smokers. Current and former smokers had higher risk for non-skin cancer (HR 1.30; 95% CI: 1.19, 1.42 and HR 1.24; 95% CI: 1.17, 1.32). Smoking was associated with a higher rate of death from cancer (HR 1.26; 95% CI 1.19-1.33) and chronic lung disease (HR 1.48; 95% CI 1.15-1.92). Former and current smokers had a higher adjusted risk for de novo vascular disease (PVD, CVD), CAD (adjusted RR 1.1; 95% Cl: 1.09-1.12). In dialysis patients, smoking was associated with higher rates of all-cause mortality, cardiovascular mortality, respiratory failure, chronic lung disease and malignancy along with higher risks of non-skin cancers, de novo vascular disease and chronic lung disease.
Sections du résumé
BACKGROUND
BACKGROUND
The association of smoking with new-onset cardiovascular disease, chronic lung disease, malignancy and mortality in dialysis is well-known. The smoking prevalence and its association with clinical outcome was assessed.
METHODS
METHODS
Multicentre cohort study using 'ANZDATA' Registry, 57 838 adults who commenced dialysis (>3 months) between 1990 and 2016 were included. Patients' demographics, initial dialysis modality, presence of comorbidities and smoking history are predictors. The primary outcome was all-cause mortality. Secondary outcomes were smoking prevalence, cause-specific mortality, non-skin cancers, cardiovascular and chronic lung diseases.
RESULTS
RESULTS
Of the 57 838 patients, 56 512 (mean age of 58.9 ± 15.1 years, 40.1% female, 43% diabetic), had data on smoking history with 13.6% current, 40.7% former and 45.6% never smokers. Former and current smokers had 10% (HR 1.10; 95% CI: 1.08, 1.13) and 22%(HR 1.22; 95% CI: 1.18, 1.26) higher risk of all-cause mortality. They were 13% (HR 1.13; 95% CI: 1.09, 1.18) and 23% (HR 1.23; 95% CI: 1.17, 1.29) for CVD mortality. Smoking was associated with higher mortality from respiratory failure (HR 1.59; 95% CI: 1.13, 2.23, p = .073 and HR 1.33; 95% CI: 1.01, 1.74, p = .042) for current and former smokers. Current and former smokers had higher risk for non-skin cancer (HR 1.30; 95% CI: 1.19, 1.42 and HR 1.24; 95% CI: 1.17, 1.32). Smoking was associated with a higher rate of death from cancer (HR 1.26; 95% CI 1.19-1.33) and chronic lung disease (HR 1.48; 95% CI 1.15-1.92). Former and current smokers had a higher adjusted risk for de novo vascular disease (PVD, CVD), CAD (adjusted RR 1.1; 95% Cl: 1.09-1.12).
CONCLUSIONS
CONCLUSIONS
In dialysis patients, smoking was associated with higher rates of all-cause mortality, cardiovascular mortality, respiratory failure, chronic lung disease and malignancy along with higher risks of non-skin cancers, de novo vascular disease and chronic lung disease.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
21-27Subventions
Organisme : International Society of Nephrology Fellowship
Informations de copyright
© 2022 Asian Pacific Society of Nephrology.
Références
WHO. WHO report on the global tobacco epidemic 2011. WHO; 2017.
WHO. WHO global report on trends in prevalence of tobacco smoking 2000-2025. 2nd ed. WHO; 2018.
Cooper RG. Effect of tobacco smoking on renal function. Indian J Med Res. 2006;124:261-268.
Molander L, Hansson A, Lunell E, Alainentalo L, Hoffmann M, Larsson R. Pharmacokinetics of nicotine in kidney failure. Clin Pharmacol Ther. 2000;68(3):250-260. doi:10.1067/mcp.2000.109006
Foley RN, Herzog CA, Collins AJ. Smoking and cardiovascular outcomes in dialysis patients: the United States renal data system wave 2 study. Kidney Int. 2003;63(4):1462-1467. doi:10.1046/j.1523-1755.2003.00860.x
Elihimas Júnior UF, Elihimas HC, Lemos VM, et al. Smoking as risk factor for chronic kidney disease: systematic review. J Bras Nefrol. 2014;36(4):519-528. doi:10.5935/0101-2800.20140074
Foley RN. Clinical epidemiology of cardiovascular disease in chronic kidney disease. J Ren Care. 2010;36(SUPPL. 1):4-8. doi:10.1111/j.1755-6686.2010.00171.x
McDonald SP, Maguire GP, Hoy WE. Validation of self-reported cigarette smoking in a remote Australian aboriginal community. Aust N Z J Public Health. 2003;27(1):57-60. doi:10.1111/j.1467-842X.2003.tb00380.x
U.S. Department of Health and Human Services. The biology and behavioral basis for smoking-attributable disease. How Tobacco Smoke Causes Disease: The Biology and Behavioral Basis for Smoking-Attributable Disease: A Report of the Surgeon General. National Center for Biotechnology Information (NCBI) - National Library of Medicine; 2010:792.
Benowitz NL. Cigarette smoking and cardiovascular disease: pathophysiology and implications for treatment. Prog Cardiovasc Dis. 2003;46(1):91-111. doi:10.1016/S0033-0620(03)00087-2
Trajceska L, Selim G, Zdraveska M, Dimitrievska D, Mladenovska D, Sikole A. Active smoking is associated with lower dialysis adequacy in prevalent dialysis patients. Open Access Maced J Med Sci. 2019;7(21):3615-3618. doi:10.3889/oamjms.2019.851
Lindson-Hawley NLT. Cochrane database of systematic reviews interventions to reduce harm from continued tobacco use (review). Published Online. 2016;10:1-19. doi:10.1002/14651858.CD005231.pub3
Tobacco smoking-Australian Institute of Health and Welfare. Accessed January 1, 2022. https://www.aihw.gov.au/reports/australias-health/tobacco-smoking
Current cigarette smoking among adults in the United States | CDC. Accessed January 1, 2022. https://www.cdc.gov/tobacco/data_statistics/fact_sheets/adult_data/cig_smoking/index.htm
Vandenbroucke JP, Von Elm E, Altman DG, et al. Strengthening the reporting of observational studies in epidemiology (STROBE): explanation and elaboration. Ann Intern Med. 2007;147(8):W. doi:10.7326/0003-4819-147-8-200710160-00010-w1
Wolbers M, Koller MT, Witteman JCM, Steyerberg EW. Prognostic models with competing risks methods and application to coronary risk prediction. Epidemiology. 2009;20(4):555-561. doi:10.1097/EDE.0b013e3181a39056
https://alraziuni.edu.ye/uploads/pdf/book1/HealthandSociety/StatisticalMethodsinMedicalResearch_4thed_2002.pdf. Accessed September 12, 2020.
Tobacco smoking-Australian Institute of Health and Welfare. Accessed November 29, 2020. https://www.aihw.gov.au/reports/australias-health/tobacco-smoking
Cigarette smoking among adults and trends in smoking cessation-United States, 2008. Accessed September 20, 2022. https://www.cdc.gov/mmwr/preview/mmwrhtml/mm5844a2.htm
Pesce G, Marcon A, Calciano L, et al. Time and age trends in smoking cessation in Europe. PLoS One. 2019;14(2):e0211976. doi:10.1371/JOURNAL.PONE.0211976
Yang JJ, Yu D, Wen W, et al. Tobacco smoking and mortality in Asia: a pooled meta-analysis. JAMA Netw Open. 2019;2(3):e191474. doi:10.1001/JAMANETWORKOPEN.2019.1474
Soucie JM, McClellan WM. Early death in dialysis patients: risk factors and impact on incidence and mortality rates. J Am Soc Nephrol. 1996;7(10):2169-2175.
Koch M, Trapp R, Kulas W, Grabensee B. Critical limb ischaemia as a main cause of death in patients with end-stage renal disease: a single-Centre study. Nephrol Dial Transplant. 2004;19(10):2547-2552. doi:10.1093/ndt/gfh404
Wagner Z, Molnár M, Molnár GA, et al. Serum carboxymethyllysine predicts mortality in hemodialysis patients. Am J Kidney Dis. 2006;47(2):294-300. doi:10.1053/j.ajkd.2005.10.010
Fishbane S, Youn S, Flaster E, Adam G, Maesaka JK. Ankle-arm blood pressure index as a predictor of mortality in hemodialysis patients. Am J Kidney Dis. 1996;27(5):668-672. doi:10.1016/S0272-6386(96)90101-8
Zimmermann J, Herrlinger S, Pruy A, Metzger T, Wanner C. Inflammation enhances cardiovascular risk and mortality in hemodialysis patients. Kidney Int. 1999;55(2):648-658. doi:10.1046/j.1523-1755.1999.00273.x
Shoji T, Emoto M, Shinohara K, et al. Diabetes mellitus, aortic stiffness, and cardiovascular mortality in end-stage renal disease. J Am Soc Nephrol. 2001;12(10):2117-2124.
Jungers P, Massy ZA, Nguyen Khoa T, et al. Incidence and risk factors of atherosclerotic cardiovascular accidents in predialysis chronic renal failure patients: a prospective study. Nephrol Dial Transplant. 1997;12(12):2597-2602. doi:10.1093/ndt/12.12.2597
Mc Causland FR, Brunelli SM, Waikar SS. Association of smoking with cardiovascular and infection-related morbidity and mortality in chronic hemodialysis. Clin J Am Soc Nephrol. 2012;7(11):1827-1835. doi:10.2215/CJN.03880412
Groenewald P, Vos T, Norman R, et al. Estimating the burden of disease attributable to smoking in South Africa in 2000. S Afr Med J. 2007;97(8 Pt 2):674-681.
Pham TM, Fujino Y, Ide R, et al. Mortality attributable to cigarette smoking in a cohort study in Japan. Eur J Epidemiol. 2007;22(9):599-605. doi:10.1007/s10654-007-9161-y