Structural principles of B cell antigen receptor assembly.


Journal

Nature
ISSN: 1476-4687
Titre abrégé: Nature
Pays: England
ID NLM: 0410462

Informations de publication

Date de publication:
12 2022
Historique:
received: 18 07 2022
accepted: 05 10 2022
pubmed: 14 10 2022
medline: 3 12 2022
entrez: 13 10 2022
Statut: ppublish

Résumé

The B cell antigen receptor (BCR) is composed of a membrane-bound class M, D, G, E or A immunoglobulin for antigen recognition

Identifiants

pubmed: 36228656
doi: 10.1038/s41586-022-05412-7
pii: 10.1038/s41586-022-05412-7
pmc: PMC10499536
mid: NIHMS1930256
doi:

Substances chimiques

Receptors, Antigen, B-Cell 0
Immunoglobulin Fab Fragments 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

156-161

Subventions

Organisme : NICHD NIH HHS
ID : DP1 HD087988
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI145656
Pays : United States
Organisme : NIGMS NIH HHS
ID : U24 GM129547
Pays : United States

Informations de copyright

© 2022. The Author(s), under exclusive licence to Springer Nature Limited.

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Auteurs

Ying Dong (Y)

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.

Xiong Pi (X)

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.

Frauke Bartels-Burgahn (F)

Signaling Research Centers BIOSS and CIBSS, Freiburg, Germany.
Department of Molecular Immunology, Faculty of Biology, University of Freiburg, Freiburg, Germany.

Deniz Saltukoglu (D)

Signaling Research Centers BIOSS and CIBSS, Freiburg, Germany.
Department of Molecular Immunology, Faculty of Biology, University of Freiburg, Freiburg, Germany.

Zhuoyi Liang (Z)

Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
HHMI, Boston Children's Hospital, Boston, MA, USA.
Department of Genetics, Harvard Medical School, Boston, MA, USA.

Jianying Yang (J)

Signaling Research Centers BIOSS and CIBSS, Freiburg, Germany.
Department of Molecular Immunology, Faculty of Biology, University of Freiburg, Freiburg, Germany.

Frederick W Alt (FW)

Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA.
HHMI, Boston Children's Hospital, Boston, MA, USA.
Department of Genetics, Harvard Medical School, Boston, MA, USA.

Michael Reth (M)

Signaling Research Centers BIOSS and CIBSS, Freiburg, Germany. michael.reth@bioss.uni-freiburg.de.
Department of Molecular Immunology, Faculty of Biology, University of Freiburg, Freiburg, Germany. michael.reth@bioss.uni-freiburg.de.

Hao Wu (H)

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA. wu@crystal.harvard.edu.
Program in Cellular and Molecular Medicine, Boston Children's Hospital, Boston, MA, USA. wu@crystal.harvard.edu.

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Classifications MeSH