Cellular shape reinforces niche to stem cell signaling in the small intestine.
Journal
Science advances
ISSN: 2375-2548
Titre abrégé: Sci Adv
Pays: United States
ID NLM: 101653440
Informations de publication
Date de publication:
14 Oct 2022
14 Oct 2022
Historique:
entrez:
14
10
2022
pubmed:
15
10
2022
medline:
15
10
2022
Statut:
ppublish
Résumé
Niche-derived factors regulate tissue stem cells, but apart from the mechanosensory pathways, the effect of niche geometry is not well understood. We used organoids and bioengineered tissue culture platforms to demonstrate that the conical shape of Lgr5
Identifiants
pubmed: 36240269
doi: 10.1126/sciadv.abm1847
pmc: PMC9565803
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
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