Detection of

EPHI, Ethiopian Public Health Institute EPTB, extrapulmonary tuberculosis MDR, multidrug resistance MTB, Mycobacterium tuberculosis MTBC, Mycobacterium tuberculosis complex Mycobacterium tuberculosis NTRL, National Tuberculosis Reference Laboratory PTB, pulmonary tuberculosis RIF, rifampicin RR-TB, rifampicin-resistant tuberculosis SPSS, Statistical Package for Social Sciences TB, tuberculosis WHO, World Health Organization Xpert MTB/RIF frequency rifampicin resistance

Journal

IJID regions
ISSN: 2772-7076
Titre abrégé: IJID Reg
Pays: England
ID NLM: 9918418183106676

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 27 07 2022
revised: 31 08 2022
accepted: 01 09 2022
entrez: 17 10 2022
pubmed: 18 10 2022
medline: 18 10 2022
Statut: epublish

Résumé

This study aimed to determine the frequencies and trends of Data were collected retrospectively from patient registries. Laboratory-based data were extracted from the national tuberculosis (TB) referral laboratory database. All patients referred to the National Tuberculosis Reference Laboratory (NTRL) for TB diagnosis from all over the country between March 1, 2014 and September 30, 2021, and tested using the Xpert MTB/RIF assay, were included. The extracted data were entered into a Microsoft Excel sheet and analyzed by Statistical Package for Social Sciences (SPSS) version 23. Among a total of 13 772 individuals tested using the Xpert MTB/RIF assay, the majority (8223; 59.7%) were males, and 48.5% (6678) of the individuals were aged between 15 and 39 years. The frequency of TB and RR-TB remains high in the study setting. RR-TB was found to have a statistically significant association with previous anti-TB medication treatment. As a result, improving treatment adherence in recognized instances could assist in preventing MTB and RR-TB cases.

Identifiants

pubmed: 36247095
doi: 10.1016/j.ijregi.2022.09.001
pii: S2772-7076(22)00113-8
pmc: PMC9556786
doi:

Types de publication

Journal Article

Langues

eng

Pagination

97-103

Subventions

Organisme : FIC NIH HHS
ID : D43 TW009127
Pays : United States

Informations de copyright

© 2022 The Author(s).

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Auteurs

Getu Diriba (G)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Ayinalem Alemu (A)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.
Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia.

Habteyes Hailu Tola (HH)

Department of Public Health, College of Health Sciences, Selale University, Fiche, Ethiopia.

Kirubel Eshetu (K)

USAID Eliminate TB Project, Management Sciences for Health, Addis Ababa, Ethiopia.

Bazezew Yenew (B)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Misikir Amare (M)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Biniyam Dagne (B)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Hilina Mollalign (H)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Waganeh Sinshaw (W)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Yeshiwork Abebaw (Y)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Getachew Seid (G)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Mengistu Tadesse (M)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Betselot Zerihun (B)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Melak Getu (M)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Shewki Moga (S)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Abyot Meaza (A)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Dinka Fekadu Gamtesa (DF)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Zigba Tefera (Z)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Amanuel Wondimu (A)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Michael Hailu (M)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Bedo Buta (B)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Muluwork Getahun (M)

National Tuberculosis Reference Laboratory, Ethiopian Public Health Institute, Addis Ababa, Ethiopia.

Abebaw Kebede (A)

Department of Microbial, Cellular and Molecular Biology, College of Natural and Computational Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
Africa Centers for Disease Control and Prevention, Addis Ababa, Ethiopia.

Classifications MeSH