Clinical factors associated with failed sentinel lymph node mapping in endometrial cancer.


Journal

Gynecologic oncology reports
ISSN: 2352-5789
Titre abrégé: Gynecol Oncol Rep
Pays: Netherlands
ID NLM: 101652231

Informations de publication

Date de publication:
Dec 2022
Historique:
received: 06 08 2022
revised: 29 09 2022
accepted: 05 10 2022
entrez: 17 10 2022
pubmed: 18 10 2022
medline: 18 10 2022
Statut: epublish

Résumé

Sentinel lymph node (SLN) mapping is a highly accurate surgical technique for detecting metastases in endometrial cancer. The objective of this study was to identify clinical factors associated with failed mapping. All patients with endometrial cancer undergoing minimally-invasive staging and planned SLN biopsy from 1/1/2017 to 12/31/2020 at a single institution were identified retrospectively. Demographic, clinicopathologic and treatment data were obtained. Data were compared using descriptive statistics. Univariate and multivariable logistic regression were performed to identify predictors of failed mapping. 819 patients were identified with a mean age of 64.6 years (range 26-93) and mean BMI of 35.6 kg/m SLN mapping has a high success in patients undergoing minimally-invasive surgical staging for endometrial cancer. Increasing BMI, high risk histology, and lymph node metastases are risk factors for failed mapping.

Identifiants

pubmed: 36249905
doi: 10.1016/j.gore.2022.101080
pii: S2352-5789(22)00160-6
pmc: PMC9554829
doi:

Types de publication

Journal Article

Langues

eng

Pagination

101080

Informations de copyright

© 2022 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Alison A Garrett (AA)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Alyssa Wield (A)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Brigid Mumford (B)

Department of Obstetrics, Gynecology and Reproductive Medicine, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Isabel Janmey (I)

Department of Obstetrics, Gynecology and Reproductive Medicine, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Li Wang (L)

Clinical and Translation Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.

Philip Grosse (P)

Clinical and Translation Science Institute, University of Pittsburgh, Pittsburgh, PA, USA.

Emily MacArthur (E)

Department of Obstetrics, Gynecology and Reproductive Medicine, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Ronald Buckanovich (R)

Magee-Womens Research Institute, Pittsburgh, PA, USA.

Madeleine Courtney-Brooks (M)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Paniti Sukumvanich (P)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Jessica Berger (J)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Alexander B Olawaiye (AB)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Haider Mahdi (H)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.
Magee-Womens Research Institute, Pittsburgh, PA, USA.

Michelle Boisen (M)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Robert P Edwards (RP)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.
Magee-Womens Research Institute, Pittsburgh, PA, USA.

Lan Coffman (L)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.
Magee-Womens Research Institute, Pittsburgh, PA, USA.

Sarah E Taylor (SE)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Jamie Lesnock (J)

Division of Gynecologic Oncology, UPMC Magee-Womens Hospital, Pittsburgh, PA, USA.

Classifications MeSH