Opportunities and challenges in stem cell therapy in cardiovascular diseases: Position standing in 2022.

Bone marrow Cardiac diseases Clinical trials MSCs Pre-clinical trials Stem cell therapy iPSCs

Journal

Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society
ISSN: 1319-0164
Titre abrégé: Saudi Pharm J
Pays: Saudi Arabia
ID NLM: 9705695

Informations de publication

Date de publication:
Sep 2022
Historique:
received: 12 02 2022
accepted: 17 06 2022
entrez: 17 10 2022
pubmed: 18 10 2022
medline: 18 10 2022
Statut: ppublish

Résumé

This study intends to evaluate the development, importance, pre-clinical and clinical study evaluation of stem cell therapy for the treatment of cardiovascular disease. Cardiovascular disease is one of the main causes of fatality in the whole world. Though there are great progressions in the pharmacological and other interventional treatment options, heart diseases remain a common disorder that causes long-term warnings. Recent accession promotes the symptoms and slows down the adverse effects regarding cardiac remodelling. But they cannot locate the problems of immutable loss of cardiac tissues. In this case, stem cell treatment holds a promising challenge. Stem cells are the cells that are capable of differentiating into many cells according to their needs. So, it is assumed that these cells can distinguish into many cells and if these cells can be individualized into cardiac cells then they can be used to replace the damaged tissues of the heart. There is some abridgment in this therapy, none the less stem cell therapy remains a hopeful destination in the treatment of heart disease.

Identifiants

pubmed: 36249945
doi: 10.1016/j.jsps.2022.06.017
pii: S1319-0164(22)00165-7
pmc: PMC9563042
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1360-1371

Informations de copyright

© 2022 The Author(s).

Déclaration de conflit d'intérêts

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

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Auteurs

Shabnur Mahmud (S)

School of Health and Life Sciences, Department of Pharmaceutical Sciences, North South University, Dhaka 1229, Bangladesh.

Safaet Alam (S)

Pharmaceutical Sciences Research Division, BCSIR Laboratories, Dhaka, Bangladesh Council of Scientific and Industrial Research (BCSIR), Dr. Qudrat-I-Khuda Road, Dhanmondi, Dhaka 1205, Bangladesh.

Nazim Uddin Emon (NU)

Department of Pharmacy, Faculty of Science and Engineering, International Islamic University Chittagong, Chittagong 4318, Bangladesh.

Umme Habiba Boby (UH)

Department of Pharmacy, Faculty of Science and Engineering, International Islamic University Chittagong, Chittagong 4318, Bangladesh.
Department of Pharmacy, Faculty of Science and Engineering, International Islamic University Chittagong, Chittagong 4318, Bangladesh.

Firoj Ahmed (F)

Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Dhaka, Dhaka 1205, Bangladesh.

A S M Monjur-Al-Hossain (ASM)

Department of Pharmaceutical Technology, Faculty of Pharmacy, University of Dhaka, Dhaka 1205, Bangladesh.

Afroza Tahamina (A)

Department of Botany, Faculty of Biological Sciences, University of Chittagong, Chattogram 4331, Bangladesh.

Sajib Rudra (S)

Department of Botany, Faculty of Biological Sciences, University of Chittagong, Chattogram 4331, Bangladesh.

Marzina Ajrin (M)

Department of Pharmacy, University of Science and Technology Chittagong, Chittagong 4202, Bangladesh.

Classifications MeSH