Hierarchical Bayesian modeling of the relationship between task-related hemodynamic responses and cortical excitability.
Bayesian data analysis
excitability
finger tapping
maximum entropy on the mean
near-infrared spectroscopy
paired associative stimulation
transcranial magnetic stimulation
Journal
Human brain mapping
ISSN: 1097-0193
Titre abrégé: Hum Brain Mapp
Pays: United States
ID NLM: 9419065
Informations de publication
Date de publication:
15 02 2023
15 02 2023
Historique:
revised:
10
09
2022
received:
08
06
2022
accepted:
18
09
2022
pubmed:
18
10
2022
medline:
28
1
2023
entrez:
17
10
2022
Statut:
ppublish
Résumé
Investigating the relationship between task-related hemodynamic responses and cortical excitability is challenging because it requires simultaneous measurement of hemodynamic responses while applying noninvasive brain stimulation. Moreover, cortical excitability and task-related hemodynamic responses are both associated with inter-/intra-subject variability. To reliably assess such a relationship, we applied hierarchical Bayesian modeling. This study involved 16 healthy subjects who underwent simultaneous Paired Associative Stimulation (PAS10, PAS25, Sham) while monitoring brain activity using functional Near-Infrared Spectroscopy (fNIRS), targeting the primary motor cortex (M1). Cortical excitability was measured by Motor Evoked Potentials (MEPs), and the motor task-related hemodynamic responses were measured using fNIRS 3D reconstructions. We constructed three models to investigate: (1) PAS effects on the M1 excitability, (2) PAS effects on fNIRS hemodynamic responses to a finger tapping task, and (3) the correlation between PAS effects on M1 excitability and PAS effects on task-related hemodynamic responses. Significant increase in cortical excitability was found following PAS25, whereas a small reduction of the cortical excitability was shown after PAS10 and a subtle increase occurred after sham. Both HbO and HbR absolute amplitudes increased after PAS25 and decreased after PAS10. The probability of the positive correlation between modulation of cortical excitability and hemodynamic activity was 0.77 for HbO and 0.79 for HbR. We demonstrated that PAS stimulation modulates task-related cortical hemodynamic responses in addition to M1 excitability. Moreover, the positive correlation between PAS modulations of excitability and hemodynamics brought insight into understanding the fundamental properties of cortical function and cortical excitability.
Identifiants
pubmed: 36250709
doi: 10.1002/hbm.26107
pmc: PMC9875942
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
876-900Subventions
Organisme : CIHR
ID : MOP 133619
Pays : Canada
Informations de copyright
© 2022 The Authors. Human Brain Mapping published by Wiley Periodicals LLC.
Références
Neurophotonics. 2021 Jan;8(1):012101
pubmed: 33442557
Hum Brain Mapp. 2018 Jan;39(1):218-231
pubmed: 29024165
Sci Rep. 2022 Feb 10;12(1):2316
pubmed: 35145148
Front Neurosci. 2019 Feb 28;13:84
pubmed: 30872985
Neuroimage. 2003 Sep;20(1):479-88
pubmed: 14527608
Hum Brain Mapp. 2020 Aug 1;41(11):3019-3033
pubmed: 32386115
Rofo. 2011 Oct;183(10):956-63
pubmed: 21972043
Neuroimage. 2011 Jan 1;54(1):313-27
pubmed: 20656036
Hum Brain Mapp. 2018 Aug;39(8):3241-3252
pubmed: 29665228
Clin Neurophysiol. 2017 Nov;128(11):2140-2164
pubmed: 28938144
Neuroinformatics. 2019 Oct;17(4):515-545
pubmed: 30649677
Clin Endocrinol (Oxf). 2007 Mar;66(3):387-93
pubmed: 17302873
Brain. 2000 Mar;123 Pt 3:572-84
pubmed: 10686179
Hum Brain Mapp. 2023 Feb 15;44(3):876-900
pubmed: 36250709
Science. 2007 Sep 28;317(5846):1918-21
pubmed: 17901333
Neuroimage. 2016 Dec;143:175-195
pubmed: 27561712
J Biomed Opt. 2018 Jan;23(1):1-4
pubmed: 29374404
Brain Stimul. 2019 Nov - Dec;12(6):1526-1536
pubmed: 31296402
Neuroimage. 2011 Jan 1;54(1):234-43
pubmed: 20682353
Magn Reson Imaging. 2006 May;24(4):495-505
pubmed: 16677956
Neuroimage. 2021 Dec 15;245:118708
pubmed: 34743050
Comput Intell Neurosci. 2011;2011:879716
pubmed: 21584256
Sci Rep. 2021 Mar 16;11(1):5964
pubmed: 33727581
Neuroimage. 2007 Mar;35(1):149-65
pubmed: 17234435
Neuroimage. 2017 Aug 15;157:531-544
pubmed: 28619655
Brain Topogr. 2008 Sep;21(1):1-10
pubmed: 18791818
Proc Natl Acad Sci U S A. 1992 Jun 15;89(12):5675-9
pubmed: 1608978
Science. 1977 Dec 23;198(4323):1264-7
pubmed: 929199
Comput Psychiatr. 2017 Oct 01;1:24-57
pubmed: 29601060
Neuroimage. 2018 Jul 15;175:413-424
pubmed: 29655936
Front Hum Neurosci. 2013 Dec 03;7:823
pubmed: 24348369
Hum Brain Mapp. 2019 Oct 1;40(14):4072-4090
pubmed: 31188535
Magn Reson Med. 2015 Nov;74(5):1492-501
pubmed: 25421603
J Physiol. 2010 Jul 1;588(Pt 13):2291-304
pubmed: 20478978
Exp Brain Res. 2007 Aug;181(4):555-60
pubmed: 17530233
PLoS One. 2013;8(2):e55969
pubmed: 23418485
Philos Trans R Soc Lond B Biol Sci. 2021 Jan 4;376(1815):20190624
pubmed: 33190604
Front Psychiatry. 2017 May 29;8:95
pubmed: 28611693
Clin Neurophysiol. 2015 Jun;126(6):1071-1107
pubmed: 25797650
Brain Stimul. 2014 May-Jun;7(3):372-80
pubmed: 24630849
Neurology. 2022 Apr 26;:
pubmed: 35473762
PLoS One. 2015 Mar 23;10(3):e0120731
pubmed: 25799422
J Neurosci. 2004 Mar 31;24(13):3379-85
pubmed: 15056717
J Pers Med. 2021 Oct 21;11(11):
pubmed: 34834410
J Neurosci Methods. 2018 Nov 1;309:91-108
pubmed: 30107210
Hum Brain Mapp. 2021 Oct 15;42(15):4823-4843
pubmed: 34342073
Neuron. 2017 Sep 27;96(1):17-42
pubmed: 28957666
Clin Neurophysiol. 2009 Dec;120(12):2008-2039
pubmed: 19833552
J Physiol. 2005 Jun 15;565(Pt 3):1039-52
pubmed: 15845584
Brain Topogr. 2016 Jan;29(1):162-81
pubmed: 25609211
Neuroimage. 2006 Jul 15;31(4):1475-86
pubmed: 16650778
Neuroimage. 2014 Jan 15;85 Pt 1:6-27
pubmed: 23684868
IEEE Trans Pattern Anal Mach Intell. 1984 Jun;6(6):721-41
pubmed: 22499653
Neuroimage. 2017 Nov 15;162:289-296
pubmed: 28912081
J Neurosci Methods. 2018 Jul 15;305:36-45
pubmed: 29758234
Neuroimage. 2008 Aug 1;42(1):343-56
pubmed: 18511305
Magn Reson Med. 1992 Jun;25(2):390-7
pubmed: 1614324
PLoS One. 2017 Oct 5;12(10):e0186007
pubmed: 28982146
Neuroimage. 2021 Jan 15;225:117496
pubmed: 33181352
Electroencephalogr Clin Neurophysiol. 1991 Apr;81(2):90-101
pubmed: 1708719
Neuroimage. 2016 Jan 1;124(Pt A):498-508
pubmed: 26334836
Neuroimage. 2020 Aug 15;217:116839
pubmed: 32387625
Brain Stimul. 2013 Jul;6(4):576-81
pubmed: 23376041
Neuroimage. 2014 Jan 15;85 Pt 1:64-71
pubmed: 23810973
Hum Brain Mapp. 2014 Apr;35(4):1740-9
pubmed: 23670997
Opt Express. 2009 Oct 26;17(22):20178-90
pubmed: 19997242
Hum Brain Mapp. 2016 May;37(5):1661-83
pubmed: 26931511
Proc Natl Acad Sci U S A. 2007 Jul 17;104(29):12169-74
pubmed: 17616584
Neurosurg Clin N Am. 2011 Apr;22(2):133-9, vii
pubmed: 21435566
Front Neurosci. 2020 Jul 28;14:746
pubmed: 32848543
Neuroimage. 2015 Oct 15;120:164-75
pubmed: 26188259
J Neurophysiol. 2022 Jan 1;127(1):204-212
pubmed: 34936818
Front Neurosci. 2016 Mar 22;10:102
pubmed: 27047325
Clin Neurophysiol. 2021 Oct;132(10):2639-2653
pubmed: 34344609
Neuron. 2002 Jan 31;33(3):341-55
pubmed: 11832223
Appl Opt. 2005 Apr 10;44(11):2140-53
pubmed: 15835360
Neuroimage. 2012 Jul 16;61(4):1120-8
pubmed: 22330315
Cereb Cortex. 2010 May;20(5):1037-45
pubmed: 19684247
Neuroimage. 2014 Jan 15;85 Pt 1:192-201
pubmed: 23796546
Neuroimage. 2017 Jul 15;155:25-49
pubmed: 28450140
Neuroscience. 1983 Apr;8(4):791-7
pubmed: 6306504
J Biomed Opt. 2014 Feb;19(2):026010
pubmed: 24525860
Brain Stimul. 2013 May;6(3):330-9
pubmed: 22770886
Exp Brain Res. 1999 Nov;129(2):317-24
pubmed: 10591905