Bilateral Primary Non-Hodgkin's Lymphoma of the Lacrimal Sac: A Case Report.
chemotherapy
dacryocystitis
endoscopic dacryocystorhinostomy
lacrimal sac
primary non-hodgkin's lymphoma
Journal
Cureus
ISSN: 2168-8184
Titre abrégé: Cureus
Pays: United States
ID NLM: 101596737
Informations de publication
Date de publication:
Sep 2022
Sep 2022
Historique:
accepted:
13
09
2022
entrez:
19
10
2022
pubmed:
20
10
2022
medline:
20
10
2022
Statut:
epublish
Résumé
Primary non-Hodgkin's lymphoma of the lacrimal sac is extremely rare, usually representing secondary involvement of systemic malignancy. We report a case of bilateral primary non-Hodgkin's lymphoma of the lacrimal sac presenting with bilateral medial canthal swelling for one month which was preceded by a history of chronic bilateral epiphora and a recurrent history of dacryocystitis. The symptoms partially responded to systemic antibiotics for the past three years. Clinical examination revealed bilateral diffuse erythematous medial canthal swelling extending to the upper cheeks. CT of the orbits and paranasal sinuses demonstrated soft tissue masses involving bilateral lacrimal sacs and ducts. Endoscopic dacryocystorhinostomy (DCR) with excision biopsy of both lacrimal sac was performed and histopathologically confirmed the diagnosis of extranodal marginal zone B-cell lymphoma. She completed six cycles of chemotherapy. The symptoms subsided and radiologically showed a significant reduction of soft tissue mass at bilateral nasolacrimal sacs and ducts after completion of chemotherapy. Recurrent atypical presentation of dacryocystitis with suboptimal response to standard treatment should raise a suspicion of secondary cause. Histopathological examination is therefore crucial to avoid delays in diagnosis and treatment.
Identifiants
pubmed: 36258989
doi: 10.7759/cureus.29114
pmc: PMC9559744
doi:
Types de publication
Case Reports
Langues
eng
Pagination
e29114Informations de copyright
Copyright © 2022, Arjamilah et al.
Déclaration de conflit d'intérêts
The authors have declared that no competing interests exist.
Références
Chin Med J (Engl). 2014;127(1):120-4
pubmed: 24384436
Am J Ophthalmol. 1956 Oct;42(4 Part 1):561-6
pubmed: 13372631
Br J Ophthalmol. 2006 Aug;90(8):936-7
pubmed: 16854834
Eur Ann Otorhinolaryngol Head Neck Dis. 2010 Nov;127(5):165-72
pubmed: 21036121
Br J Ophthalmol. 2006 Aug;90(8):1004-9
pubmed: 16672329
Saudi J Ophthalmol. 2012 Apr;26(2):235-9
pubmed: 23960998
Orbit. 2010 Oct;29(5):298-306
pubmed: 20958177
Ophthalmology. 1986 Aug;93(8):1055-63
pubmed: 3763155
Eye (Lond). 2003 Jul;17(5):599-606
pubmed: 12855966
Arch Ophthalmol. 2003 Sep;121(9):1330-3
pubmed: 12963620
Ophthalmology. 2002 Jul;109(7):1214-7; discussion 1217-8
pubmed: 12093640
Med J Malaysia. 2013 Jun;68(3):269-70
pubmed: 23749022
Radiother Oncol. 2001 May;59(2):145-51
pubmed: 11325442
Hum Pathol. 1982 Feb;13(2):148-62
pubmed: 7042523
J Fr Ophtalmol. 2015 Dec;38(10):e237
pubmed: 26616299
Invest Ophthalmol Vis Sci. 2001 Mar;42(3):566-74
pubmed: 11222512