A retrospective cohort study comparing differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in European tax-based healthcare systems (THS) versus social health insurance systems.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
19 10 2022
Historique:
received: 10 03 2022
accepted: 29 09 2022
entrez: 19 10 2022
pubmed: 20 10 2022
medline: 22 10 2022
Statut: epublish

Résumé

In Europe, tax-based healthcare systems (THS) and social health insurance systems (SHI) coexist. We examined differences in 30-day mortality among critically ill patients aged ≥ 70 years treated in intensive care units in a THS or SHI. Retrospective cohort study. 2406 (THS n = 886; SHI n = 1520) critically ill ≥ 70 years patients in 129 ICUs. Generalized estimation equations with robust standard errors were chosen to create population average adjusted odds ratios (aOR). Data were adjusted for patient-specific variables, organ support and health economic data. The primary outcome was 30-day-mortality. Numerical differences between SHI and THS in SOFA scores (6 ± 3 vs. 5 ± 3; p = 0.002) were observed, but clinical frailty scores were similar (> 4; 17% vs. 14%; p = 0.09). Higher rates of renal replacement therapy (18% vs. 11%; p < 0.001) were found in SHI (aOR 0.61 95%CI 0.40-0.92; p = 0.02). No differences regarding intubation rates (68% vs. 70%; p = 0.33), vasopressor use (67% vs. 67%; p = 0.90) and 30-day-mortality rates (47% vs. 50%; p = 0.16) were found. Mortality remained similar between both systems after multivariable adjustment and sensitivity analyses. The retrospective character of this study. Baseline risk and mortality rates were similar between SHI and THS. The type of health care system does not appear to have played a role in the intensive care treatment of critically ill patients ≥ 70 years with COVID-19 in Europe.

Identifiants

pubmed: 36261587
doi: 10.1038/s41598-022-21580-y
pii: 10.1038/s41598-022-21580-y
pmc: PMC9580441
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

17460

Informations de copyright

© 2022. The Author(s).

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Auteurs

Bernhard Wernly (B)

Center for Public Health and Healthcare Research, Paracelsus Medical University of Salzburg, 5020, Salzburg, Austria.
Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, 5020, Salzburg, Austria.

Hans Flaatten (H)

Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Department of Anaestesia and Intensive Care, Haukeland University Hospital, 5021, Bergen, Norway.

Michael Beil (M)

Deptartment of Medical Intensive Care, Faculty of Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, 91120, Jersualem, Israel.

Jesper Fjølner (J)

Department of Anesthesia and Intensive Care, Viborg Regional Hospital, 8800, Viborg, Denmark.

Raphael Romano Bruno (RR)

Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Duesseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.

Antonio Artigas (A)

Department of Intensive Care Medicine, CIBER Enfermedades Respiratorias, Corporacion Sanitaria Universitaria Parc Tauli, Autonomous University of Barcelona, 08208, Sabadell, Spain.

Bernardo Bollen Pinto (BB)

Department of Acute Medicine, Geneva University Hospitals, 1205, Geneva, Switzerland.

Joerg C Schefold (JC)

Department of Intensive Care Medicine, Inselspital, Universitätsspital, University of Bern, 3010, Bern, Switzerland.

Malte Kelm (M)

Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Duesseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.

Sviri Sigal (S)

Deptartment of Medical Intensive Care, Faculty of Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, 91120, Jersualem, Israel.

Peter Vernon van Heerden (PV)

Deptartment of Anesthesia, Intensive Care and Pain Medicine, Faculty of Medicine, Hadassah Medical Center, Hebrew University of Jerusalem, 91120, Jerusalem, Israel.

Wojciech Szczeklik (W)

Center for Intensive Care and Perioperative Medicine, Jagiellonian University Medical College, 31-008, Krakow, Poland.

Muhammed Elhadi (M)

Faculty of Medicine, University of Tripoli, R6XF+46G, Tripoli, Libya.

Michael Joannidis (M)

Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, 6020, Innsbruck, Austria.

Richard Rezar (R)

Clinic of Internal Medicine II, Department of Cardiology and Intensive Care, Paracelsus Medical University of Salzburg, 5020, Salzburg, Austria.

Sandra Oeyen (S)

Department of Intensive Care 1K12IC, Ghent University Hospital, 9000, Ghent, Belgium.

Georg Wolff (G)

Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Duesseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.

Brian Marsh (B)

Mater Misericordiae University Hospital, Dublin, D07 R2WY, Ireland.

Finn H Andersen (FH)

Department of Anaesthesia and Intensive Care, Ålesund Hospital, 6017, Ålesund, Norway.
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology, 7491, Trondheim, Norway.

Rui Moreno (R)

Centro Hospitalar de Lisboa Central, Lisbon, Portugal.
Faculdade de Ciências Médicas de Lisboa, Nova Medical School, Lisbon, Portugal.
Faculdade de Ciências da Saúde, Universidade da Beira Interior, Covilha, Portugal.

Sarah Wernly (S)

Department of Internal Medicine, General Hospital Oberndorf, Teaching Hospital of the Paracelsus Medical University Salzburg, 5020, Salzburg, Austria.

Susannah Leaver (S)

General Intensive Care, St. George´s University Hospital NHS Foundation Trust, London, SW17 0QT, UK.

Ariane Boumendil (A)

Inserm, Service de réanimation, Institut Pierre-Louis d'épidémiologie et de Santé Publique, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184, Rue du Faubourg-Saint-Antoine, 75012, Paris, France.

Dylan W De Lange (DW)

Department of Intensive Care Medicine, University Medical Center, University Utrecht, 3584 CX, Utrecht, The Netherlands.

Bertrand Guidet (B)

Inserm, Service de réanimation, Institut Pierre-Louis d'épidémiologie et de Santé Publique, Hôpital Saint-Antoine, AP-HP, Sorbonne Université, 184, Rue du Faubourg-Saint-Antoine, 75012, Paris, France.

Stefan Perings (S)

Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Duesseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany.

Christian Jung (C)

Department of Cardiology, Pulmonology and Vascular Medicine, Medical Faculty, Heinrich-Heine-University Duesseldorf, Moorenstraße 5, 40225, Düsseldorf, Germany. christian.jung@med.uni-duesseldorf.de.

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