Relationship between blood pressure and intraocular pressure in the JPHC-NEXT eye study.
Journal
Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288
Informations de publication
Date de publication:
19 10 2022
19 10 2022
Historique:
received:
02
07
2022
accepted:
12
10
2022
entrez:
19
10
2022
pubmed:
20
10
2022
medline:
22
10
2022
Statut:
epublish
Résumé
Although a positive link between hypertension and intraocular pressure (IOP) has been suggested, the individual effects of systolic and diastolic blood pressure (SBP and DBP, respectively) on IOP remain unclear, particularly among Japanese populations. Here, we conducted a large-scale, cross-sectional study to determine individual and combined effects of SBP/DBP and hypertension on IOP. In total, 6783 Japanese people aged over 40 years underwent systemic and ophthalmological examinations, including measurements of blood pressure and IOP, conducted using non-contact tonometers. After adjusting for a priori known confounding factors, SBP and DBP levels were found to be positively correlated with IOP levels. The multivariable-adjusted odds ratio when comparing the hypertensive and normotensive groups for the prevalence of ocular hypertension was 1.88 (95% confidence interval, 1.14-3.08). When analysing the combined effects of SBP and DBP on ocular hypertension, SBP elevation had a greater effect on ocular hypertension than DBP increase. In conclusion, SBP and DBP levels and the prevalence of systemic hypertension were found to be positively associated with IOP levels and the prevalence of ocular hypertension in an ophthalmologically healthy Japanese population. Our findings suggest that systemic blood pressure control may be key for controlling IOP.
Identifiants
pubmed: 36261671
doi: 10.1038/s41598-022-22301-1
pii: 10.1038/s41598-022-22301-1
pmc: PMC9582013
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
17493Informations de copyright
© 2022. The Author(s).
Références
Lancet. 2021 Sep 11;398(10304):957-980
pubmed: 34450083
Eye (Lond). 2014 Jun;28(6):672-9
pubmed: 24603415
Hypertension. 2019 May;73(5):944-950
pubmed: 30852921
N Engl J Med. 2019 Jul 18;381(3):243-251
pubmed: 31314968
Arch Ophthalmol. 1995 Feb;113(2):216-21
pubmed: 7864755
J Diabetes Investig. 2010 Oct 19;1(5):212-28
pubmed: 24843435
Br J Ophthalmol. 1975 Apr;59(4):211-5
pubmed: 1138846
Am J Epidemiol. 1983 Aug;118(2):280-7
pubmed: 6881131
Arch Ophthalmol. 2002 Jun;120(6):714-20; discussion 829-30
pubmed: 12049575
Br J Ophthalmol. 2006 Mar;90(3):262-7
pubmed: 16488940
Ophthalmology. 1993 May;100(5):643-50
pubmed: 8493005
Am J Ophthalmol. 2010 Aug;150(2):279-86
pubmed: 20570236
Can J Ophthalmol. 2013 Jun;48(3):136-7
pubmed: 23769772
Ophthalmology. 2003 May;110(5):908-14
pubmed: 12750088
Am J Ophthalmol. 2005 Jul;140(1):131-2
pubmed: 16038656
J Cataract Refract Surg. 2010 Aug;36(8):1289-95
pubmed: 20656150
Nutrients. 2019 Jul 21;11(7):
pubmed: 31330870
Int J Obes (Lond). 2010 Jul;34(7):1209-17
pubmed: 20157320
Invest Ophthalmol Vis Sci. 1990 Nov;31(11):2361-6
pubmed: 2243000
Lancet. 2011 Apr 16;377(9774):1367-77
pubmed: 21453963
Br J Ophthalmol. 2008 Sep;92(9):1175-9
pubmed: 18669541
Ophthalmology. 1999 Oct;106(10):2016-22
pubmed: 10519601
Ophthalmol Eye Dis. 2012 Apr 30;4:43-64
pubmed: 23650457
Acta Ophthalmol. 2008 Jun;86(4):434-9
pubmed: 18039350
J Clin Hypertens (Greenwich). 2016 Feb;18(2):95-100
pubmed: 26234374
South Med J. 2005 Jan;98(1):28-32
pubmed: 15678637
Br J Ophthalmol. 1975 Dec;59(12):717-20
pubmed: 1218183
Am J Ophthalmol. 2008 Jul;146(1):69-76
pubmed: 18486096
Am J Ophthalmol. 2007 Sep;144(3):461-2
pubmed: 17765433
Circ J. 2013;77(9):2226-31
pubmed: 23902998
Curr Opin Ophthalmol. 2019 Mar;30(2):82-88
pubmed: 30562241
Ophthalmology. 2006 Sep;113(9):1613-7
pubmed: 16828504
Br J Ophthalmol. 2005 Mar;89(3):284-7
pubmed: 15722304
Br J Ophthalmol. 1987 Oct;71(10):766-71
pubmed: 3676147
Arch Ophthalmol. 1984 Jun;102(6):883-7
pubmed: 6732570
Ophthalmology. 2005 Oct;112(10):1661-9
pubmed: 16111758
Am J Ophthalmol. 2002 Oct;134(4):499-512
pubmed: 12383806
J Hypertens. 2018 Oct;36(10):1953-2041
pubmed: 30234752
Invest Ophthalmol Vis Sci. 1992 Jun;33(7):2224-8
pubmed: 1607232
Hypertens Res. 2019 Sep;42(9):1235-1481
pubmed: 31375757
Prog Brain Res. 2008;173:25-30
pubmed: 18929099
J Epidemiol. 2020 Jan 5;30(1):46-54
pubmed: 30713262
J Am Heart Assoc. 2016 Mar 25;5(3):e003053
pubmed: 27016576
Br J Ophthalmol. 2019 Sep;103(9):1209-1216
pubmed: 30910873
Am J Ophthalmol. 2014 Sep;158(3):615-27.e9
pubmed: 24879946