Clinically relevant dosing and pharmacokinetics of DNA-encoded antibody therapeutics in a sheep model.
antibody gene transfer
electroporation
oncology
plasmid – gene delivery
sheep
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2022
2022
Historique:
received:
12
08
2022
accepted:
14
09
2022
entrez:
20
10
2022
pubmed:
21
10
2022
medline:
21
10
2022
Statut:
epublish
Résumé
DNA-encoded delivery and
Identifiants
pubmed: 36263202
doi: 10.3389/fonc.2022.1017612
pmc: PMC9574358
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1017612Informations de copyright
Copyright © 2022 Hollevoet, Thomas, Compernolle, Vermeire, De Smidt, De Vleeschauwer, Smith, Fisher, Dewilde, Geukens and Declerck.
Déclaration de conflit d'intérêts
Authors TS and PF are employees of Inovio Pharmaceuticals and as such receives salary and benefits, including ownership of stock and stock options, from the company. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The authors declare that this study received funding from Inovio Pharmaceuticals under a sponsored research agreement. The funder had the following involvement with the study: contribution to study design and materials, interpretation of data, review of the article, and decision to submit it for publication.
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