Sublethal cadmium exposure in the freshwater snail Lymnaea stagnalis meets a deficient, poorly responsive metallothionein system while evoking oxidative and cellular stress.
Biomarker battery
Digestive gland
Gastropoda
Metal detoxification
Metallothionein deficiency
Journal
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
ISSN: 1532-0456
Titre abrégé: Comp Biochem Physiol C Toxicol Pharmacol
Pays: United States
ID NLM: 100959500
Informations de publication
Date de publication:
Jan 2023
Jan 2023
Historique:
received:
12
08
2022
revised:
29
09
2022
accepted:
12
10
2022
pubmed:
21
10
2022
medline:
23
11
2022
entrez:
20
10
2022
Statut:
ppublish
Résumé
The Great Pond snail Lymnaea stagnalis (Gastropoda, Hygrophila) is a wide-spread freshwater gastropod, being considered as a model organism for research in many fields of biology, including ecotoxicology. The aim of the present study was to explore the Cd sensitivity of L. stagnalis through the measurement of a biomarker battery for oxidative, toxic and cellular stress. The interpretation of biomarker parameters occurred against the background of a truncated metallothionein protein with a limited Cd-binding capacity. Individuals of L. stagnalis were exposed through 14 days to uncontaminated water (controls) or to low (30 μg · L
Identifiants
pubmed: 36265756
pii: S1532-0456(22)00225-3
doi: 10.1016/j.cbpc.2022.109490
pii:
doi:
Substances chimiques
Metallothionein
9038-94-2
Cadmium
00BH33GNGH
Biomarkers
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
109490Informations de copyright
Copyright © 2022 The Author(s). Published by Elsevier Inc. All rights reserved.
Déclaration de conflit d'intérêts
Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.