Evaluation of graphene oxide, chitosan and their complex as antibacterial agents and anticancer apoptotic effect on HeLa cell line.

HeLa cells P53 gene antibacterial anticancer chitosan complex graphene oxide

Journal

Frontiers in microbiology
ISSN: 1664-302X
Titre abrégé: Front Microbiol
Pays: Switzerland
ID NLM: 101548977

Informations de publication

Date de publication:
2022
Historique:
received: 20 04 2022
accepted: 08 08 2022
entrez: 21 10 2022
pubmed: 22 10 2022
medline: 22 10 2022
Statut: epublish

Résumé

Cancer and bacterial infection are the most serious problems threatening people's lives worldwide. However, the overuse of antibiotics as antibacterial and anticancer treatments can cause side effects and lead to drug-resistant bacteria. Therefore, developing natural materials with excellent antibacterial and anticancer activity is of great importance. In this study, different concentrations of chitosan (CS), graphene oxide (GO), and graphene oxide-chitosan composite (GO-CS) were tested to inhibit the bacterial growth of gram-positive (

Identifiants

pubmed: 36267179
doi: 10.3389/fmicb.2022.922324
pmc: PMC9577200
doi:

Types de publication

Journal Article

Langues

eng

Pagination

922324

Informations de copyright

Copyright © 2022 Ashry, El Bahgy, Mohamed, Alsubhi, Alrefaei, Binothman, Alharbi, Selim, Almuhayawi, Alharbi, Nagshabandi, Saad, El-Saadony and Sitohy.

Déclaration de conflit d'intérêts

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.

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Auteurs

Noha M Ashry (NM)

Department of Agriculture Microbiology, Faculty of Agriculture, Benha University, Qalubia, Egypt.

Halla E K El Bahgy (HEK)

Department of Veterinary Hygiene and Management, Faculty of Veterinary Medicine, Benha University, Banha, Egypt.

Abdelkader Mohamed (A)

Department of Soil and Water Research, Nuclear Research Center, Egyptian Atomic Energy Authority, Abou Zaabl, Egypt.

Nouf H Alsubhi (NH)

Department of Biological Sciences, College of Science and Arts, King Abdulaziz University, Rabigh, Saudi Arabia.

Ghadeer I Alrefaei (GI)

Department of Biology, College of Science, University of Jeddah, Jeddah, Saudi Arabia.

Najat Binothman (N)

Department of Chemistry, College of Sciences and Arts, King Abdulaziz University, Rabigh, Saudi Arabia.

Mona Alharbi (M)

Department of Biochemistry, College of Science, King Saud University, Riyadh, Saudi Arabia.

Samy Selim (S)

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Jouf University, Sakaka, Saudi Arabia.

Mohammed S Almuhayawi (MS)

Department of Medical Microbiology and Parasitology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Mohanned T Alharbi (MT)

Department of Medical Microbiology and Parasitology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia.

Mohammed K Nagshabandi (MK)

Department of Medical Microbiology and Parasitology, Faculty of Medicine, University of Jeddah, Jeddah, Saudi Arabia.

Ahmed M Saad (AM)

Department of Biochemistry, Faculty of Agriculture Zagazig University, Zagazig, Egypt.

Mohamed T El-Saadony (MT)

Department of Agricultural Microbiology, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.

Basel Sitohy (B)

Department of Radiation Sciences, Oncology, Umeå University, Umeå, Sweden.
Department of Clinical Microbiology, Infection and Immunology, Umeå University, Umeå, Sweden.

Classifications MeSH