Transcellular biosynthesis of leukotriene B

Cell biology Immunology

Journal

iScience
ISSN: 2589-0042
Titre abrégé: iScience
Pays: United States
ID NLM: 101724038

Informations de publication

Date de publication:
21 Oct 2022
Historique:
received: 28 04 2022
revised: 25 07 2022
accepted: 23 09 2022
entrez: 21 10 2022
pubmed: 22 10 2022
medline: 22 10 2022
Statut: epublish

Résumé

Neutrophil swarming is an emergent host defense mechanism triggered by targets larger than a single neutrophil's capacity to phagocytose. Swarming synergizes neutrophil functions, including chemotaxis, phagocytosis, and reactive oxygen species (ROS) production, and coordinates their deployment by many interacting neutrophils. The potent inflammatory lipid mediator leukotriene B

Identifiants

pubmed: 36267914
doi: 10.1016/j.isci.2022.105226
pii: S2589-0042(22)01498-5
pmc: PMC9576560
doi:

Types de publication

Journal Article

Langues

eng

Pagination

105226

Subventions

Organisme : NIGMS NIH HHS
ID : P01 GM095467
Pays : United States
Organisme : NIAID NIH HHS
ID : R01 AI095338
Pays : United States
Organisme : NIGMS NIH HHS
ID : R35 GM139430
Pays : United States

Informations de copyright

© 2022 The Authors.

Déclaration de conflit d'intérêts

M.K.M. reports consultation fees from Vericel, Pulsethera, NED Biosystems, GenMark Diagnostics, Clear Creek Bio, and Day Zero Diagnostics; grant support from Thermo Fisher Scientific and Genentech; medical editing/writing fees from UpToDate, outside the submitted work. M.K.M. also reports patents 14/110,443 and 15/999,463 pending.

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Auteurs

Alex Hopke (A)

Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02129, USA.
Harvard Medical School, Boston, MA 02115, USA.
Shriners Hospital for Children, Boston, MA 02114, USA.

Tian Lin (T)

Harvard Medical School, Boston, MA 02115, USA.
Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.

Allison K Scherer (AK)

Harvard Medical School, Boston, MA 02115, USA.
Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.

Ashley E Shay (AE)

Harvard Medical School, Boston, MA 02115, USA.
Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Kyle D Timmer (KD)

Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.

Brittany Wilson-Mifsud (B)

Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.

Michael K Mansour (MK)

Harvard Medical School, Boston, MA 02115, USA.
Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA.

Charles N Serhan (CN)

Harvard Medical School, Boston, MA 02115, USA.
Center for Experimental Therapeutics and Reperfusion Injury, Department of Anesthesiology, Perioperative, and Pain Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Daniel Irimia (D)

Center for Engineering in Medicine and Surgery, Massachusetts General Hospital, Boston, MA 02129, USA.
Harvard Medical School, Boston, MA 02115, USA.
Shriners Hospital for Children, Boston, MA 02114, USA.

Bryan P Hurley (BP)

Harvard Medical School, Boston, MA 02115, USA.
Mucosal Immunology and Biology Research Center, Massachusetts General Hospital, Boston, MA 02114, USA.

Classifications MeSH