Whole slide image data utilization informed by digital diagnosis patterns.
Journal
Journal of pathology informatics
ISSN: 2229-5089
Titre abrégé: J Pathol Inform
Pays: United States
ID NLM: 101528849
Informations de publication
Date de publication:
2022
2022
Historique:
accepted:
28
11
2021
entrez:
21
10
2022
pubmed:
22
10
2022
medline:
22
10
2022
Statut:
epublish
Résumé
Despite the benefits of digital pathology, data storage and management of digital whole slide images introduces new logistical and infrastructure challenges to traditionally analog pathology labs. Our goal was to analyze pathologist slide diagnosis patterns to determine the minimum number of pixels required during the diagnosis. We developed a method of using pathologist viewing patterns to vary digital image resolution across virtual slides, which we call variable resolution images. An additional pathologist reviewed the variable resolution images to determine if diagnoses could still be rendered. Across all slides, the pathologists rarely zoomed in to the full resolution level. As a result, the variable resolution images are significantly smaller than the original whole slide images. Despite the reduction in image sizes, the final pathologist reviewer could still proide diagnoses on the variable resolution slide images. Future studies will be conducted to understand variability in resolution requirements between and within pathologists. These findings have the potential to dramatically reduce the data storage requirements of high-resolution whole slide images.
Identifiants
pubmed: 36268057
doi: 10.1016/j.jpi.2022.100113
pii: S2153-3539(22)00707-6
pmc: PMC9577055
doi:
Types de publication
Journal Article
Langues
eng
Pagination
100113Subventions
Organisme : NCI NIH HHS
ID : R01 CA222831
Pays : United States
Informations de copyright
© 2022 The Authors.
Références
J Pathol Inform. 2017 Jul 25;8:29
pubmed: 28828200
J Pathol Inform. 2018 Nov 21;9:40
pubmed: 30607307
Am J Clin Pathol. 2011 Dec;136(6):889-95
pubmed: 22095374
J Pathol Inform. 2021 Apr 07;12:17
pubmed: 34221633
J Digit Imaging. 2009 Jun;22(3):250-8
pubmed: 17999112
J Digit Imaging. 2016 Oct;29(5):583-614
pubmed: 27576909
Histopathology. 2011 Jan;58(2):211-6
pubmed: 21323948
J Am Med Inform Assoc. 2021 Aug 13;28(9):1874-1884
pubmed: 34260720
Hum Pathol. 2013 Mar;44(3):357-64
pubmed: 22835956
Arch Pathol Lab Med. 2019 Dec;143(12):1545-1555
pubmed: 31173528
Arch Pathol Lab Med. 2019 Feb;143(2):222-234
pubmed: 30307746
J Pathol Inform. 2019 Mar 08;10:9
pubmed: 30984469
Indian J Radiol Imaging. 2008 Nov;18(4):287-9
pubmed: 19774182
J Pathol Inform. 2018 May 25;9:20
pubmed: 29910969
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
J Digit Imaging. 2018 Feb;31(1):32-41
pubmed: 28681097
Histopathology. 2015 Aug;67(2):185-92
pubmed: 25487230