A systematic review and meta-analysis on delaying surgery for urothelial carcinoma of bladder and upper tract urothelial carcinoma: Implications for the COVID19 pandemic and beyond.
bladder cancer
bladder carcinoma
delay in surgery
delayed treatment
time-to-treatment
ureteral neoplasms
urinary bladder neoplasms
urothelial carcinoma
Journal
Frontiers in surgery
ISSN: 2296-875X
Titre abrégé: Front Surg
Pays: Switzerland
ID NLM: 101645127
Informations de publication
Date de publication:
2022
2022
Historique:
received:
20
02
2022
accepted:
23
08
2022
entrez:
21
10
2022
pubmed:
22
10
2022
medline:
22
10
2022
Statut:
epublish
Résumé
The COVID-19 pandemic has led to competing strains on hospital resources and healthcare personnel. Patients with newly diagnosed invasive urothelial carcinomas of bladder (UCB) upper tract (UTUC) may experience delays to definitive radical cystectomy (RC) or radical nephro-ureterectomy (RNU) respectively. We evaluate the impact of delaying definitive surgery on survival outcomes for invasive UCB and UTUC. We searched for all studies investigating delayed urologic cancer surgery in Medline and Embase up to June 2020. A systematic review and meta-analysis was performed. We identified a total of 30 studies with 32,591 patients. Across 13 studies ( A delay from diagnosis of UCB or UTUC to definitive RC or RNU was associated with poorer survival outcomes. This was not the case for patients who received neoadjuvant chemotherapy.
Identifiants
pubmed: 36268209
doi: 10.3389/fsurg.2022.879774
pmc: PMC9577485
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
879774Informations de copyright
© 2022 Leow, Tan, Tan, Tan, Chan, Tikkinen, Kamat, Sengupta, Meng, Shariat, Roupret, Decaestecker, Vasdev, Chong, Enikeev, Giannarini, Ficarra and Teoh.
Déclaration de conflit d'intérêts
The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.
Références
BJU Int. 2008 Jul;102(2):172-6
pubmed: 18341624
Int J Radiat Oncol Biol Phys. 2010 May 1;77(1):119-24
pubmed: 19665319
Jpn J Clin Oncol. 2002 Jan;32(1):14-8
pubmed: 11932357
Eur Urol Oncol. 2019 Jul;2(4):390-396
pubmed: 31277775
BJU Int. 2008 Sep;102(8):1045
pubmed: 18840144
Int J Urol. 2011 Aug;18(8):576-84
pubmed: 21699582
Eur Urol. 2021 Jan;79(1):62-79
pubmed: 32593530
Curr Oncol. 2015 Feb;22(1):e20-6
pubmed: 25684993
Urology. 2020 Oct;144:269-270
pubmed: 32687841
Urol Oncol. 2019 Feb;37(2):116-122
pubmed: 30509868
BJU Int. 2007 Nov;100(5):1015-20
pubmed: 17784888
Tumori. 2018 Dec;104(6):434-437
pubmed: 28665471
J Urol. 2003 Jan;169(1):110-5; discussion 115
pubmed: 12478115
Urol Oncol. 2018 Jan;36(1):10.e15-10.e22
pubmed: 29031419
Cancers (Basel). 2021 Jun 30;13(13):
pubmed: 34208888
BJU Int. 2010 Mar;105(6):812-7
pubmed: 19732052
Eur Urol Oncol. 2020 Apr;3(2):239-249
pubmed: 31668714
J Urol. 2005 Nov;174(5):1777-81; discussion 1781
pubmed: 16217282
Cancer. 2009 Mar 1;115(5):988-96
pubmed: 19142878
J Endourol. 2012 May;26(5):566-73
pubmed: 21879886
Urology. 2019 Nov;133:157-163
pubmed: 31421144
Eur Urol. 2018 Jul;74(1):10-14
pubmed: 29653885
Eur Urol. 2021 May;79(5):700
pubmed: 33288273
Br J Cancer. 2009 Dec 3;101 Suppl 2:S1-4
pubmed: 19956152
BJU Int. 2011 Oct;108(8 Pt 2):E284-8
pubmed: 21244611
Eur Urol. 2020 Dec;78(6):893-906
pubmed: 32972792
J Urol. 2016 Jun;195(6):1704-9
pubmed: 26807928
J Urol. 2016 Apr;195(4 Pt 1):880-5
pubmed: 26598426
J Urol. 2006 Jan;175(1):78-83; discussion 83
pubmed: 16406875
Lancet. 2003 Jun 7;361(9373):1927-34
pubmed: 12801735
Urol Oncol. 2016 Apr;34(4):166.e1-6
pubmed: 26705102
Cancer. 2012 Jan 1;118(1):44-53
pubmed: 21598245
Eur Urol. 2017 Jan;71(1):96-108
pubmed: 27370177
World J Urol. 2021 Dec;39(12):4295-4303
pubmed: 34031748
J Urol. 2006 Apr;175(4):1262-7; discussion 1267
pubmed: 16515975
J Urol. 2009 Oct;182(4):1318-24
pubmed: 19683272
BJU Int. 2017 May;119 Suppl 5:10-18
pubmed: 28544294
Eur Urol. 2020 Dec;78(6):786-811
pubmed: 32616405
Eur Urol Oncol. 2018 Sep;1(4):292-304
pubmed: 31100250
Minerva Urol Nefrol. 2018 Oct;70(5):494-500
pubmed: 29595035
Ann Oncol. 2014 Sep;25(9):1783-1788
pubmed: 24915872
Urol Oncol. 2017 Oct;35(10):602.e1-602.e9
pubmed: 28647395
Minerva Urol Nefrol. 2020 Jun;72(3):376-383
pubmed: 32225135
J Clin Oncol. 2020 Oct 20;38(30):3538-3546
pubmed: 32795225
JAMA. 2000 Apr 19;283(15):2008-12
pubmed: 10789670
J Urol. 2017 Sep;198(3):552-559
pubmed: 28456635
BMJ. 2009 Jul 21;339:b2535
pubmed: 19622551
J Surg Oncol. 2014 Sep;110(4):468-75
pubmed: 25059848
Cancer. 2009 Apr 1;115(7):1435-47
pubmed: 19215030
Minerva Urol Nefrol. 2020 Jun;72(3):369-375
pubmed: 32202401
Can Urol Assoc J. 2008 Apr;2(2):102-8
pubmed: 18542741
Urol Oncol. 2012 May-Jun;30(3):266-72
pubmed: 20869888
Cancer. 2019 Jun 15;125(12):2011-2017
pubmed: 30840335
Eur Urol. 2020 Aug;78(2):265-275
pubmed: 32507625
CA Cancer J Clin. 2018 Nov;68(6):394-424
pubmed: 30207593
ANZ J Surg. 2016 Dec;86(12):1042-1045
pubmed: 26331718
N Engl J Med. 2003 Aug 28;349(9):859-66
pubmed: 12944571
BMJ. 1991 Aug 24;303(6800):437-40
pubmed: 1912834
Scand J Urol Nephrol. 2004;38(3):231-5
pubmed: 15204377
Eur Urol. 2020 Jul;78(1):21-28
pubmed: 32376137