Cytomegalovirus in the transplant setting: Where are we now and what happens next? A report from the International CMV Symposium 2021.
cellular therapy
cytomegalovirus immunoglobulin (CMVIG)
hematopoietic stem cell transplant
prophylaxis
solid organ transplant
treatment
vaccine
Journal
Transplant infectious disease : an official journal of the Transplantation Society
ISSN: 1399-3062
Titre abrégé: Transpl Infect Dis
Pays: Denmark
ID NLM: 100883688
Informations de publication
Date de publication:
Dec 2022
Dec 2022
Historique:
revised:
16
09
2022
received:
20
06
2022
accepted:
27
09
2022
pubmed:
23
10
2022
medline:
24
12
2022
entrez:
22
10
2022
Statut:
ppublish
Résumé
The CMV Symposium in September 2021 was an international conference dedicated to cytomegalovirus (CMV) infection after solid organ or hematopoietic stem cell transplantation. This review provides an overview of the presentations given by the expert faculty, supplemented with educational clinical cases. Topics discussed include CMV epidemiology and diagnosis, the burden of CMV infection and disease, CMV-specific immunity and management of CMV in transplant settings. Major advances in the prevention and treatment of CMV in the past decade and increased understanding of CMV immunity have led to improved patient outcomes. In the future, management algorithms may be individualized based on the transplant recipient's immune profile, which will mark the start of a new era for patients with CMV.
Identifiants
pubmed: 36271650
doi: 10.1111/tid.13977
pmc: PMC10078482
doi:
Substances chimiques
Antiviral Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e13977Subventions
Organisme : Biotest AG
Informations de copyright
© 2022 The Authors. Transplant Infectious Disease published by Wiley Periodicals LLC.
Références
Curr Infect Dis Rep. 2019 Nov 15;21(11):45
pubmed: 31732823
Clin Transplant. 2021 Jun;35(6):e14285
pubmed: 33713374
Nat Rev Immunol. 2020 Feb;20(2):113-127
pubmed: 31666730
Haematologica. 2021 Feb 01;106(2):363-374
pubmed: 31879324
FEMS Microbiol Rev. 2018 Mar 1;42(2):137-145
pubmed: 29361041
Transpl Infect Dis. 2021 Apr;23(2):e13504
pubmed: 33169931
Clin Infect Dis. 2018 Oct 15;67(9):1395-1402
pubmed: 29635432
Sci Transl Med. 2018 Apr 11;10(436):
pubmed: 29643233
J Heart Lung Transplant. 2009 Oct;28(10):1050-6
pubmed: 19782286
PLoS Pathog. 2015 Oct 20;11(10):e1005227
pubmed: 26484870
Med Microbiol Immunol. 2019 Aug;208(3-4):391-403
pubmed: 31011793
Kidney Int. 2004 Jul;66(1):329-37
pubmed: 15200441
Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6110-6112
pubmed: 29875141
J Heart Lung Transplant. 2020 Nov;39(11):1300-1312
pubmed: 32962919
Transpl Infect Dis. 2022 Dec;24(6):e13977
pubmed: 36271650
Clin Infect Dis. 2019 Apr 8;68(8):1420-1426
pubmed: 30137245
Transpl Infect Dis. 2021 Apr;23(2):e13483
pubmed: 33012092
Nat Med. 2010 Mar;16(3):339-45
pubmed: 20139992
Am J Transplant. 2009 Nov;9(11):2453-8
pubmed: 19843027
Am J Transplant. 2021 Apr;21(4):1622-1628
pubmed: 33320429
Clin Transplant. 2008 Jan-Feb;22(1):89-97
pubmed: 18217909
Biol Blood Marrow Transplant. 2019 Feb;25(2):369-381
pubmed: 30292744
J Heart Lung Transplant. 2009 May;28(5):461-7
pubmed: 19416774
Am J Transplant. 2019 Sep;19(9):2495-2504
pubmed: 30916879
Antiviral Res. 2019 Dec;172:104639
pubmed: 31654672
Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):6273-6278
pubmed: 29686064
Clin Dev Immunol. 2013;2013:637649
pubmed: 24319467
Ann Transplant. 2016 Sep 06;21:558-64
pubmed: 27595792
Transpl Infect Dis. 2021 Aug;23(4):e13687
pubmed: 34251742
Transplant Cell Ther. 2021 Dec;27(12):957-967
pubmed: 34560310
J Virol. 2021 Jun 24;95(14):e0013021
pubmed: 33893170
J Am Soc Nephrol. 2002 Oct;13(10):2577-84
pubmed: 12239248
Sci Adv. 2020 Apr 22;6(17):eaax9856
pubmed: 32494628
Lancet Infect Dis. 2011 Apr;11(4):284-92
pubmed: 21414843
Front Immunol. 2020 Oct 15;11:567531
pubmed: 33178192
Transplantation. 2020 Jul;104(7):1508-1518
pubmed: 31644496
Transplantation. 2001 Nov 27;72(10):1647-52
pubmed: 11726825
Clin Infect Dis. 2022 Sep 10;75(4):690-701
pubmed: 34864943
J Clin Invest. 2019 Nov 1;129(11):5020-5032
pubmed: 31415240
Clin Infect Dis. 2020 Apr 10;70(8):1525-1533
pubmed: 31179485
Am J Transplant. 2020 Dec;20(12):3509-3519
pubmed: 32428296
Curr Treat Options Infect Dis. 2021;13(3):123-140
pubmed: 34305463
Transplantation. 2016 Mar;100 Suppl 3:S11-8
pubmed: 26900990
Clin Infect Dis. 2020 Oct 23;71(7):e159-e169
pubmed: 31915816
Clin Infect Dis. 2014 Aug 15;59(4):473-81
pubmed: 24850801
Nat Rev Microbiol. 2021 Dec;19(12):759-773
pubmed: 34168328
Antimicrob Agents Chemother. 2018 Jun 26;62(7):
pubmed: 29712656
Clin Infect Dis. 2021 Mar 1;72(5):845-852
pubmed: 32025704
Am J Transplant. 2004 Jun;4(6):928-36
pubmed: 15147427
Immun Inflamm Dis. 2021 Dec;9(4):1554-1562
pubmed: 34525263
Transpl Infect Dis. 2020 Aug;22(4):e13289
pubmed: 32277837
J Antimicrob Chemother. 2020 Aug 1;75(8):2253-2257
pubmed: 32413116
Lancet Infect Dis. 2019 Aug;19(8):e260-e272
pubmed: 31153807
Clin Infect Dis. 2019 Apr 8;68(8):1255-1264
pubmed: 30329038
Transplantation. 2019 May;103(5):1005-1013
pubmed: 30247316
Clin Microbiol Rev. 2020 Oct 28;34(1):
pubmed: 33115722
J Infect Dis. 2020 Mar 5;221(Suppl 1):S74-S85
pubmed: 32134488
Front Cell Dev Biol. 2020 Oct 27;8:534268
pubmed: 33195184
Infect Dis Clin North Am. 2010 Jun;24(2):413-37
pubmed: 20466277
Cochrane Database Syst Rev. 2013 Feb 28;(2):CD005133
pubmed: 23450558
Antiviral Res. 2020 Apr;176:104711
pubmed: 31940472
Antiviral Res. 2022 May;201:105299
pubmed: 35354065
New Microbiol. 2018 Jul;41(3):195-202
pubmed: 30028473
Drugs. 2016 Nov;76(17):1625-1645
pubmed: 27882457
Cytometry B Clin Cytom. 2017 Mar;92(2):153-160
pubmed: 26918565
Lancet. 2011 Apr 9;377(9773):1256-63
pubmed: 21481708
JAMA. 1989 Jun 23-30;261(24):3561-6
pubmed: 2542633
Am J Transplant. 2008 May;8(5):975-83
pubmed: 18261177
Pediatr Transplant. 2016 Nov;20(7):970-980
pubmed: 27565955
Transplantation. 2018 Jun;102(6):900-931
pubmed: 29596116
Ther Adv Hematol. 2021 Mar 03;12:2040620721998124
pubmed: 33747424
J Heart Lung Transplant. 2008 Mar;27(3):297-301
pubmed: 18342752
N Engl J Med. 2017 Dec 21;377(25):2433-2444
pubmed: 29211658
Lancet Haematol. 2016 Mar;3(3):e119-27
pubmed: 26947200
Am J Transplant. 2010 Sep;10(9):2026-32
pubmed: 20883536